• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia

Trendingnow

1

Even as Elon Musk calls philanthropy ‘very hard,’ everyday Americans gave a record $617 billion—despite feeling the squeeze over the cost of living

2

Egg companies made $1.22 billion in profit off a $6 carton — now they’re buying their way out of a price-fixing case with 53 million donated eggs

3

Meet the Zillennials: The luckiest micro-generation in the workforce, born between 1993 and 1998

1

Even as Elon Musk calls philanthropy ‘very hard,’ everyday Americans gave a record $617 billion—despite feeling the squeeze over the cost of living

2

Egg companies made $1.22 billion in profit off a $6 carton — now they’re buying their way out of a price-fixing case with 53 million donated eggs

3

Meet the Zillennials: The luckiest micro-generation in the workforce, born between 1993 and 1998
Health

An experimental COVID drug was so successful that they’re shutting down trials early

By
Colin Lodewick
Colin Lodewick
Down Arrow Button Icon
By
Colin Lodewick
Colin Lodewick
Down Arrow Button Icon
April 12, 2022, 3:35 PM ET
Add Fortune on Google for similar content.

A new drug could be a godsend for patients hospitalized with COVID, and help save the most critical cases. 

A double-blind study that ended last week showed that sabizabulin, a new oral medication from pharmaceutical company Veru has the potential to cut the virus’s mortality rate in half for moderate and severe cases. It was so successful, in fact, that researchers stopped the trial early.

“What that implies is that it’s unethical to continue treating people with placebo,” Mitchell Steiner, chairman, president, and CEO of Veru, told Fortune.

While the study was originally meant to involve around 210 patients hospitalized with COVID, an early analysis of the first 150 patients showed such overwhelming success that the study’s independent data monitoring committee recommended halting it. The group of people who took the placebo pill had a 45% mortality rate, while the sabizabulin-treated group had a mortality rate of just 20%.  

Sabizabulin functions as both an antiviral and anti-inflammatory drug that targets cellular infrastructure known as microtubules. The coronavirus uses that infrastructure to travel into cells where it replicates before traveling out again to spread. 

“We disrupt that,” says Steiner, adding that sabizabulin blocks both the virus and its associated inflammatory proteins.

Steiner says that the 45% mortality rate seen in the placebo group of the sabizabulin trial has been largely consistent for patients with severe COVID since the start of the pandemic.

“That’s scary to think, that by the time you get into the hospital and you’re on oxygen, you have a fifty-fifty chance of surviving,” says Steiner. “This takes some of the scariness out of going to the hospital.”

Most COVID restrictions have disappeared across the U.S., and as the pandemic stretches into its third year, many Americans have tired of constantly being on guard. But there are still approximately 500 COVID-related deaths on average in the country every day, and Dr. Anthony Fauci has predicted a new wave coming this fall, with a potential increase over the next few weeks. 

Because of the persistent need for effective treatment for severe COVID, the third phase of Sabizabulin’s trial received “fast track” designation by the Food and Drug Administration (FDA) in January.

Veru is currently seeking emergency-use authorization of sabizabulin from the FDA, which a previous COVID treatment, remdesivir, received in May 2020. That means the drug could be available in just a few months.   

The FDA declined Fortune’s request to comment, stating that it “cannot comment on pending applications before the agency or its interactions with any manufacturers about their investigational products.”

Beyond mortality data, Veru is studying other positive effects that sabizabulin might have, including cutting down the number of days a patient stays in the ICU, and the number of days a patient is on mechanical ventilation.

And although the company is currently testing a COVID treatment, Veru’s area of expertise is oncology research, with a focus on breast and prostate cancers. Steiner says the company was previously researching sabizabulin for its cancer-fighting properties before it began pandemic research.

“We’re an oncology company and we happened to fall into the virus world because we’re in the middle of a pandemic, and we felt duty-bound,” he said. 

Steiner likens the race to find an effective treatment for severe COVID to the U.S. space program during the 20th century, which spawned “new technologies that had nothing to do with space” but found other applications. 

He says he’s confident the drug will ultimately win approval from the FDA, especially considering the fact that it did not trigger any safety concerns during testing.

Veru is currently in discussions with the Biomedical Advanced Research and Development Authority (BARDA) and other government agencies to secure an advance purchasing agreement for the drug, pending approval from the FDA.

Never miss a story: Follow your favorite topics and authors to get a personalized email with the journalism that matters most to you.

About the Author
By Colin Lodewick
See full bioRight Arrow Button Icon
Add Fortune on Google for similar content.

Latest in Health

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Fortune Secondary Logo
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • World's Most Admired Companies
  • See All Rankings
  • Lists Calendar
Sections
  • Finance
  • Fortune Crypto
  • Features
  • Leadership
  • Health
  • Commentary
  • Success
  • Retail
  • Mpw
  • Tech
  • Lifestyle
  • CEO Initiative
  • Asia
  • Politics
  • Conferences
  • Europe
  • Newsletters
  • Personal Finance
  • Environment
  • Magazine
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
  • Group Subscriptions
About Us
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Latest in Health

Photo: Paris, france
Environmentclimate change
Brutal heatwave in France is killing 2,000 people per week, undertakers are overwhelmed, and health agency says there’s worse to come
By John Leicester and The Associated PressJuly 3, 2026
2 days ago
Opti-Greens 50 Review (2026): Insights from Hands-On Testing
HealthDietary Supplements
Opti-Greens 50 Review (2026): Insights from Hands-On Testing
By Christina SnyderJuly 2, 2026
2 days ago
A man shaves wood pieces from a block.
EconomyRetirement
Economists have found an answer to slowing cognitive decline: Avoid retiring early, study finds
By Sasha RogelbergJuly 2, 2026
3 days ago
The Best Compact Ellipticals of 2026: Tested by Fitness Fanatics
HealthDietary Supplements
The Best Compact Ellipticals of 2026: Tested by Fitness Fanatics
By Emily PharesJuly 2, 2026
3 days ago
The 6 Best Exercise Bikes of 2026: Fitness Expert Reviewed
HealthDietary Supplements
The 6 Best Exercise Bikes of 2026: Fitness Expert Reviewed
By Christina SnyderJuly 1, 2026
3 days ago
kean
PoliticsCongress
Tom Kean discloses depression diagnosis behind 4-month absence from Congress: ‘until you experience it yourself, it is difficult to fully understand’
By Mike Catalini, Joey Cappelletti and The Associated PressJune 30, 2026
5 days ago

Most Popular

Even as Elon Musk calls philanthropy ‘very hard,’ everyday Americans gave a record $617 billion—despite feeling the squeeze over the cost of living
Success
Even as Elon Musk calls philanthropy ‘very hard,’ everyday Americans gave a record $617 billion—despite feeling the squeeze over the cost of living
By Preston ForeJuly 4, 2026
1 day ago
Egg companies made $1.22 billion in profit off a $6 carton — now they’re buying their way out of a price-fixing case with 53 million donated eggs
Law
Egg companies made $1.22 billion in profit off a $6 carton — now they’re buying their way out of a price-fixing case with 53 million donated eggs
By Wyatte Grantham-Philips and The Associated PressJuly 2, 2026
3 days ago
Meet the Zillennials: The luckiest micro-generation in the workforce, born between 1993 and 1998
AI
Meet the Zillennials: The luckiest micro-generation in the workforce, born between 1993 and 1998
By Nick LichtenbergJuly 3, 2026
2 days ago
Economists have found an answer to slowing cognitive decline: Avoid retiring early, study finds
Economy
Economists have found an answer to slowing cognitive decline: Avoid retiring early, study finds
By Sasha RogelbergJuly 2, 2026
3 days ago
$25 billion CEO says one-hour interviews are a waste of time—he puts candidates through six hours of tests and wants them to order wine at lunch
Success
$25 billion CEO says one-hour interviews are a waste of time—he puts candidates through six hours of tests and wants them to order wine at lunch
By Orianna Rosa RoyleJuly 3, 2026
2 days ago
Three dads started selling hats from a garage with $750—now they’ve sold $35 million worth, partnered with Gary Vee, and grown a community of fathers
Success
Three dads started selling hats from a garage with $750—now they’ve sold $35 million worth, partnered with Gary Vee, and grown a community of fathers
By Preston ForeJuly 4, 2026
21 hours ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.