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Fortune 500: Titans and Disruptors of Industry

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Hosted by Fortune Editor-in-Chief Alyson Shontell, Fortune 500: Titans and Disrupters of Industry goes in-depth with the powerful thought leaders shaping both the world of business and the very way we live. Subscribe to the show on Spotify or Apple Podcasts.
Fortune Editor-in-Chief Alyson Shontell and Khosla Ventures Founder Vinod Khosla: Graphic for Fortune 500 Titans and Disruptors of Industry podcast. Episode title: "AI and the end of work?"
NewslettersFamed investor Vinod Khosla predicts free AI labor will lead to an era of few jobs and great abundance
By Alyson ShontellMarch 4, 2026
Vinod Khosla, wearing a black suit jacket, looks forward.
AIOpenAI investor Vinod Khosla predicts today’s 5-year-olds won’t ever need to get jobs thanks to AI
By Sasha RogelbergMarch 4, 2026
Demis Hassabis, chief executive officer of Google DeepMind
SuccessThe CEO of Google DeepMind juggles another job as the founder of a multibillion-dollar startup by starting a second workday at 10 p.m.
By Emma BurleighFebruary 12, 2026
Deepmind CEO
AIGoogle Gemini boss describes working with founders Larry Page and Sergey Brin to win the AI future
By Nick LichtenbergFebruary 12, 2026
Demis Hassabis
AIGoogle’s Nobel-winning AI leader sees a ‘renaissance’ ahead—after a 10- or 15-year shakeout
By Nick LichtenbergFebruary 11, 2026
How Demis Hassabis is leading Google through an innovator’s dilemma—and made OpenAI declare ‘code red’
C-SuiteHow Demis Hassabis is leading Google through an innovator’s dilemma—and made OpenAI declare ‘code red’
By Fortune EditorsFebruary 11, 2026
Albert Bourla
SuccessPfizer CEO Albert Bourla’s best leadership advice: Being optimistic is better than being right
By Preston ForeJanuary 31, 2026
‘We’ll save the world from cancer’: Inside Pfizer CEO’s $23 billion post‑COVID bet on oncology
C-Suite‘We’ll save the world from cancer’: Inside Pfizer CEO’s $23 billion post‑COVID bet on oncology
By Nick LichtenbergJanuary 30, 2026
Pfizer CEO says he used ‘emotional blackmail’ to get employees to achieve impossible goals during COVID-19
C-SuitePfizer CEO says he used ‘emotional blackmail’ to get employees to achieve impossible goals during COVID-19
By Eva RoytburgJanuary 29, 2026
Graphic reads: Fortune Titans and Disruptors of Industry with Albert Bourla, CEO of Pfizer, Hosted by Alyson Shontell (both pictured).
C-SuitePfizer CEO on how he struck a deal with President Trump in 10 days to lower American drug costs
By Fortune EditorsJanuary 27, 2026
Jamie Dimon’s worldview: JPMorgan Chase CEO on the economy, an AI bubble, and leadership
C-SuiteJamie Dimon’s worldview: JPMorgan Chase CEO on the economy, an AI bubble, and leadership
By Fortune EditorsOctober 17, 2025
Former Vice President Kamala Harris: ‘I’m not into’ finality
PoliticsFormer Vice President Kamala Harris: ‘I’m not into’ finality
By Fortune EditorsOctober 15, 2025
Ramp founder Eric Glyman: How I built a $22.5 billion startup in 2,367 days
Big TechRamp founder Eric Glyman: How I built a $22.5 billion startup in 2,367 days
By Fortune EditorsSeptember 19, 2025
Accenture CEO weighs in on why so many AI projects have failed with 3 red flags to watch out for
SuccessAccenture CEO weighs in on why so many AI projects have failed with 3 red flags to watch out for
By Marco Quiroz-GutierrezAugust 31, 2025
Accenture CEO Julie Sweet says Fortune 500s can survive AI—but they have to be willing to reinvent themselves top to bottom
LeadershipAccenture CEO Julie Sweet says Fortune 500s can survive AI—but they have to be willing to reinvent themselves top to bottom
By Fortune EditorsAugust 30, 2025
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