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Fortune 500: Titans and Disruptors of Industry

Fortune 500: Titans and Disruptors of Industry

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Hosted by Fortune Editor-in-Chief Alyson Shontell, Fortune 500: Titans and Disrupters of Industry goes in-depth with the powerful thought leaders shaping both the world of business and the very way we live. Subscribe to the show on Spotify or Apple Podcasts.

Vinod Khosla, wearing a black suit jacket, looks forward.

AI OpenAI investor Vinod Khosla predicts today’s 5-year-olds won’t ever need to get jobs thanks to AI

By Sasha RogelbergMarch 4, 2026

Demis Hassabis, chief executive officer of Google DeepMind

Success The CEO of Google DeepMind juggles another job as the founder of a multibillion-dollar startup by starting a second workday at 10 p.m.

By Emma BurleighFebruary 12, 2026

Deepmind CEO

AI Google Gemini boss describes working with founders Larry Page and Sergey Brin to win the AI future

By Nick LichtenbergFebruary 12, 2026

Demis Hassabis

AI Google’s Nobel-winning AI leader sees a ‘renaissance’ ahead—after a 10- or 15-year shakeout

By Nick LichtenbergFebruary 11, 2026

How Demis Hassabis is leading Google through an innovator’s dilemma—and made OpenAI declare ‘code red’

C-Suite How Demis Hassabis is leading Google through an innovator’s dilemma—and made OpenAI declare ‘code red’

By Fortune EditorsFebruary 11, 2026

Albert Bourla

Success Pfizer CEO Albert Bourla’s best leadership advice: Being optimistic is better than being right

By Preston ForeJanuary 31, 2026

‘We’ll save the world from cancer’: Inside Pfizer CEO’s $23 billion post‑COVID bet on oncology

C-Suite ‘We’ll save the world from cancer’: Inside Pfizer CEO’s $23 billion post‑COVID bet on oncology

By Nick LichtenbergJanuary 30, 2026

Pfizer CEO says he used ‘emotional blackmail’ to get employees to achieve impossible goals during COVID-19

C-Suite Pfizer CEO says he used ‘emotional blackmail’ to get employees to achieve impossible goals during COVID-19

By Eva RoytburgJanuary 29, 2026

Graphic reads: Fortune Titans and Disruptors of Industry with Albert Bourla, CEO of Pfizer, Hosted by Alyson Shontell (both pictured).

C-Suite Pfizer CEO on how he struck a deal with President Trump in 10 days to lower American drug costs

By Fortune EditorsJanuary 27, 2026

Jamie Dimon’s worldview: JPMorgan Chase CEO on the economy, an AI bubble, and leadership

C-Suite Jamie Dimon’s worldview: JPMorgan Chase CEO on the economy, an AI bubble, and leadership

By Fortune EditorsOctober 17, 2025

Former Vice President Kamala Harris: ‘I’m not into’ finality

Politics Former Vice President Kamala Harris: ‘I’m not into’ finality

By Fortune EditorsOctober 15, 2025

Ramp founder Eric Glyman: How I built a $22.5 billion startup in 2,367 days

Big Tech Ramp founder Eric Glyman: How I built a $22.5 billion startup in 2,367 days

By Fortune EditorsSeptember 19, 2025

Accenture CEO weighs in on why so many AI projects have failed with 3 red flags to watch out for

Success Accenture CEO weighs in on why so many AI projects have failed with 3 red flags to watch out for

By Marco Quiroz-GutierrezAugust 31, 2025

Accenture CEO Julie Sweet says Fortune 500s can survive AI—but they have to be willing to reinvent themselves top to bottom

Leadership Accenture CEO Julie Sweet says Fortune 500s can survive AI—but they have to be willing to reinvent themselves top to bottom

By Fortune EditorsAugust 30, 2025

Accenture CEO Julie Sweet says there’s one thing you should never do if you get offered a big job you don’t feel ready for

Success Accenture CEO Julie Sweet says there’s one thing you should never do if you get offered a big job you don’t feel ready for

By Preston ForeAugust 28, 2025

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By Fortune EditorsApril 15, 2026

Billionaire philanthropist MacKenzie Scott has donated again—a week after gifting millions to a college, she's just given $70 million to Meals on Wheels America

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