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Fortune 500: Titans and Disruptors of Industry

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Hosted by Fortune Editor-in-Chief Alyson Shontell, Fortune 500: Titans and Disrupters of Industry goes in-depth with the powerful thought leaders shaping both the world of business and the very way we live. Subscribe to the show on Spotify or Apple Podcasts.
Inside Delta CEO Ed Bastian’s turnaround playbook—from bankruptcy to most profitable U.S. airline
Newsletters
Inside Delta CEO Ed Bastian’s turnaround playbook—from bankruptcy to most profitable U.S. airline
By Alyson ShontellApril 1, 2026
Photo of Vinod Khosla
Startups & Venture
Billionaire OpenAI investor Vinod Khosla predicts how awesome life could be in 2040—even if AI wipes out colleges and jobs
By Fortune EditorsMarch 7, 2026
OpenAI investor Vinod Khosla believes AI will be able to do 80% of all jobs by 2030. Here’s how life could be affordable after mass unemployment
AI
OpenAI investor Vinod Khosla believes AI will be able to do 80% of all jobs by 2030. Here’s how life could be affordable after mass unemployment
By Nick LichtenbergMarch 6, 2026
Silicon Valley investor Vinod Khosla predicts education will be free, and the future of college is ‘a real question’
Future of Work
Silicon Valley investor Vinod Khosla predicts education will be free, and the future of college is ‘a real question’
By Marco Quiroz-GutierrezMarch 6, 2026
OpenAI investor Vinod Khosla, a vocal Trump critic, agrees with the president on AI and China: ‘We are in a techno-economic war’
Big Tech
OpenAI investor Vinod Khosla, a vocal Trump critic, agrees with the president on AI and China: ‘We are in a techno-economic war’
By Nicholas GordonMarch 6, 2026
Silicon Valley legend Vinod Khosla has ‘no plans to leave California’ amid billionaire tax uproar—but he has another idea to fix the wealth loophole
Startups & Venture
Silicon Valley legend Vinod Khosla has ‘no plans to leave California’ amid billionaire tax uproar—but he has another idea to fix the wealth loophole
By Nick LichtenbergMarch 5, 2026
Fortune Editor-in-Chief Alyson Shontell and Khosla Ventures Founder Vinod Khosla: Graphic for Fortune 500 Titans and Disruptors of Industry podcast. Episode title: "AI and the end of work?"
Economy
Vinod Khosla thinks future presidential candidates should run on removing income tax for those making less than $100,000
By Catherina GioinoMarch 5, 2026
Fortune Editor-in-Chief Alyson Shontell and Khosla Ventures Founder Vinod Khosla: Graphic for Fortune 500 Titans and Disruptors of Industry podcast. Episode title: "AI and the end of work?"
Newsletters
Famed investor Vinod Khosla predicts free AI labor will lead to an era of few jobs and great abundance
By Alyson ShontellMarch 4, 2026
Vinod Khosla, wearing a black suit jacket, looks forward.
AI
OpenAI investor Vinod Khosla predicts today’s 5-year-olds won’t ever need to get jobs thanks to AI
By Sasha RogelbergMarch 4, 2026
Demis Hassabis, chief executive officer of Google DeepMind
Success
The CEO of Google DeepMind juggles another job as the founder of a multibillion-dollar startup by starting a second workday at 10 p.m.
By Emma BurleighFebruary 12, 2026
Deepmind CEO
AI
Google Gemini boss describes working with founders Larry Page and Sergey Brin to win the AI future
By Nick LichtenbergFebruary 12, 2026
Demis Hassabis
AI
Google’s Nobel-winning AI leader sees a ‘renaissance’ ahead—after a 10- or 15-year shakeout
By Nick LichtenbergFebruary 11, 2026
How Demis Hassabis is leading Google through an innovator’s dilemma—and made OpenAI declare ‘code red’
C-Suite
How Demis Hassabis is leading Google through an innovator’s dilemma—and made OpenAI declare ‘code red’
By Fortune EditorsFebruary 11, 2026
Albert Bourla
Success
Pfizer CEO Albert Bourla’s best leadership advice: Being optimistic is better than being right
By Preston ForeJanuary 31, 2026
‘We’ll save the world from cancer’: Inside Pfizer CEO’s $23 billion post‑COVID bet on oncology
C-Suite
‘We’ll save the world from cancer’: Inside Pfizer CEO’s $23 billion post‑COVID bet on oncology
By Nick LichtenbergJanuary 30, 2026
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