• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
Some Fortune Crypto pricing data is provided by Binance.
NewslettersFortune Crypto

The most important companies in crypto: Breaking down the Crypto 40 winners

By
Jeff John Roberts
Jeff John Roberts
Editor, Finance and Crypto
Down Arrow Button Icon
By
Jeff John Roberts
Jeff John Roberts
Editor, Finance and Crypto
Down Arrow Button Icon
April 10, 2023, 8:48 AM ET

It’s a dirty secret in the media industry that “best of” lists are popular, but also, in most cases, totally subjective. It’s not hard to sit around with a few work buddies to come up with some names, and then present it to the world as an authoritative ranking—and pick up some clicks in the process. Fortune lists aren’t like that—and the inaugural Fortune Crypto 40 definitely isn’t like that.

When we set out, the plan was to replicate the Fortune 500—our flagship list that ranks the biggest U.S. companies by revenue. It quickly became clear that this would be impractical, since few big players in crypto are public companies, and, of those that are, few break out their crypto-specific revenue. We also discovered that it’s not viable to compare the crypto achievements of Fidelity (which ranks No. 4 in the TradFi category) to Chainalysis (No. 1, Data) to a decentralized platform like Curve (No. 5, DeFi). And so we set out to create distinct categories that would permit apples-to-apples comparisons, and a methodology for each.

Hundreds of hours later, the list is now live, and I’m proud to say it’s the first of its kind: an authoritative ranking of crypto excellence based on empirical data (developer activity, fundraising, TVL [total value locked], and so on as the category may dictate) and in some cases, reputation, as informed by a survey of over 200 finance and crypto executives.

In some cases, this resulted in predictable outcomes—few people will be surprised to see Uniswap (No. 1, DeFi) and OpenSea (No. 1, NFTs) leading their respective categories—but also some notable omissions. Ripple and MasterCard got edged out, while financial troubles at other big players like DCG and Gemini resulted in reputational hits that kept them off this year’s list. There are also some controversial names on the list, most notably Binance (No. 2, CeFi), which fared poorly in the survey but whose other metrics were dominating, as well as JPMorgan Chase (No. 3, TradFi), whose CEO professes a hatred of crypto but has also overseen some truly innovative blockchain projects.

The Fortune Crypto 40 also recognizes back-end companies like Alchemy (No. 4, Infrastructure) that lack sizzle but have quietly become indispensable to the industry, as well as entities such as Polygon Labs (No. 3, Protocols) that support the blockchains at the core of crypto. More broadly, the list serves to recognize firms that are likely to be here for decades to come, and to hold up good actors in the crypto industry who—contrary to popular perception—outnumber the charlatans and scoundrels. We hope you can find time to review the whole list and, like us, learn more about who is really leading the way.

Finally, the female Panamanian artist who goes by IX Shells dropped an NFT version of the gorgeous blockchain-themed cover she designed for this month’s issue of Fortune magazine. If you want to own a piece of history—and support her and the crypto industry in the process—you can buy one for 0.1 ETH until the 24-hour sale ends at 1 p.m. EDT today.

Jeff John Roberts
jeff.roberts@fortune.com
@jeffjohnroberts

DECENTRALIZED NEWS

In the wake of the collapse of Signature and Silvergate, Binance.US has been relying on a middleman, Prime Trust LLC, to hold customer cash deposits. (WSJ)

A CFTC lawsuit labeling tokens as commodities underscores an ongoing turf war with the SEC, where one official described a strategy of “jurisdictional maximalization.” (Wired)

Ethereum’s Shanghai update, which will likely see owners cash out billions worth of staked ETH, goes live this week—what you need to know. (Fortune)

Dogecoin is mostly back to where it was before Elon Musk caused the price to spike with a short-lived move to make the doggy Twitter’s new logo. (Barron’s) 

The first major report from FTX’s caretaker CEO reveals a lack of accounting, including a directive to employees to “come up with some numbers? Idk.” (CoinDesk)

MEME O’ THE MOMENT

A classic Fortune cover with an NFT twist

This is the web version of Fortune Crypto, a daily newsletter. Sign up here to get it delivered free to your inbox.

About the Author
By Jeff John RobertsEditor, Finance and Crypto
LinkedIn iconTwitter icon

Jeff John Roberts is the Finance and Crypto editor at Fortune, overseeing coverage of the blockchain and how technology is changing finance.

See full bioRight Arrow Button Icon

Latest in Newsletters

Goldman Sachs' logo seen displayed on a smartphone with an AI chip and symbol in the background.
NewslettersCFO Daily
Goldman Sachs CFO on the company’s AI reboot, talent, and growth
By Sheryl EstradaDecember 10, 2025
8 minutes ago
NewslettersCIO Intelligence
Inside tractor maker CNH’s push to bring more artificial intelligence to the farm
By John KellDecember 10, 2025
1 hour ago
NewslettersTerm Sheet
5 VCs sounds off on the AI question du jour
By Amanda GerutDecember 10, 2025
2 hours ago
Hillary Super at the 2025 Victoria's Secret Fashion Show held at Steiner Studios on October 15, 2025 in New York, New York.
NewslettersCEO Daily
Activist investors are disproportionately targeting female CEOs—and it’s costing corporate America dearly
By Phil WahbaDecember 10, 2025
2 hours ago
Databricks co-founder and CEO Ali Ghodsi (right) with Fortune editorial director Andrew Nusca at Fortune Brainstorm AI 2025 in San Francisco. (Photo: Stuart Isett/Fortune)
NewslettersFortune Tech
How Databricks could achieve a trillion-dollar valuation
By Andrew NuscaDecember 10, 2025
3 hours ago
A man and robot sitting opposite each other.
AIEye on AI
The problem with ‘human in the loop’ AI? Often, it’s the humans
By Jeremy KahnDecember 9, 2025
17 hours ago

Most Popular

placeholder alt text
Economy
‘Fodder for a recession’: Top economist Mark Zandi warns about so many Americans ‘already living on the financial edge’ in a K-shaped economy 
By Eva RoytburgDecember 9, 2025
16 hours ago
placeholder alt text
Success
When David Ellison was 13, his billionaire father Larry bought him a plane. He competed in air shows before leaving it to become a Hollywood executive
By Dave SmithDecember 9, 2025
1 day ago
placeholder alt text
Banking
Jamie Dimon taps Jeff Bezos, Michael Dell, and Ford CEO Jim Farley to advise JPMorgan's $1.5 trillion national security initiative
By Nino PaoliDecember 9, 2025
18 hours ago
placeholder alt text
Uncategorized
Transforming customer support through intelligent AI operations
By Lauren ChomiukNovember 26, 2025
14 days ago
placeholder alt text
Real Estate
The 'Great Housing Reset' is coming: Income growth will outpace home-price growth in 2026, Redfin forecasts
By Nino PaoliDecember 6, 2025
4 days ago
placeholder alt text
Success
Craigslist founder signs the Giving Pledge, and his fortune will go to military families, fighting cyberattacks—and a pigeon rescue
By Sydney LakeDecember 8, 2025
2 days ago
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • Future 50
  • World’s Most Admired Companies
  • See All Rankings
Sections
  • Finance
  • Leadership
  • Success
  • Tech
  • Asia
  • Europe
  • Environment
  • Fortune Crypto
  • Health
  • Retail
  • Lifestyle
  • Politics
  • Newsletters
  • Magazine
  • Features
  • Commentary
  • Mpw
  • CEO Initiative
  • Conferences
  • Personal Finance
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
About Us
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map

© 2025 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.