The Best Probiotic Supplements for Women (2025): Expert Approved

Probiotics help keep your gut healthy by adding more good bacteria, which can also support your immune system and overall health. One way to get probiotics is through eating foods like sauerkraut, kefir, or naturally fermented pickles.

If you’re looking to boost your digestive support, improve immune balance, or reduce symptoms like bloating by taking a daily probiotic supplement, selecting the right probiotic can make a real difference in how you feel. We worked with a registered dietitian to test and evaluate the best probiotic supplements of 2025 for women.

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Our team of expert testers has tried hundreds of the most popular supplements on the market today, using our comprehensive supplement testing methodology to find the best products for all folks.

Best Probiotics for Women of 2025

• Best Probiotic for Women Overall: Ritual Synbiotic+
• Best Probiotic for Women Over 50: Nutricost Probiotic Complex
• Best Prenatal Probiotic for Women: Perelel Third Trimester Prenatal Pack
• Best Probiotic for Women for Bloating: Onnit Total Gut Health
• Best Probiotic for Women for Weight Loss: Ora Organic Trust Your Gut
• Best Probiotic for Women for Vaginal Health: O-Positiv Vaginal Probiotic

Best Probiotics for Women Comparison Table

Best Probiotic for Women Overall: Ritual Synbiotic+

Our Thoughts on Ritual Synbiotic+

Ritual’s Synbiotic+ is our pick for the best probiotic for women, thanks to its inclusion of two of the most clinically researched strains: Lactobacillus rhamnosus and Bifidobacterium animalis ssp. lactis, as well as its pre- and post-biotic support. It offers the benefits of a convenient 3-in-1 formula, with a refreshing touch of mint that makes it enjoyable to take.

Kate tried this probiotic and gave it a 5 out of 5 for her initial impression. “I love Ritual’s packaging: it’s a matte, gray bottle with clean and classy font. The font is in white on a light gray background, so it could be hard for some people to read.” She noted that the supplement facts and instructions are clearly labelled and easy to understand. The bottle is easy to open, and the pills are easy to get out of the bottle. “Someone with dexterity issues shouldn’t have too much of a problem opening it,” she said. 

She rated the ease of taking the capsule as a 3 out of 5. We love that you only take one pill, rather than two, setting it apart from some other probiotic products. 

What makes Ritual unique is its double encapsulation. Essentially, its a coating that helps protect a second capsule as it moves through your digestive system so it can break down properly. “The second, inner capsule almost looks like gold flakes that is broken down powder. You need one pill per serving,” our tester wrote. 

Whereas most probiotic supplements don’t have a distinctive taste, Kate enjoyed the minty essence you get with Ritual. She described it by writing: “There is also an overwhelming mint smell when you open the bottle, and there’s a mint aftertaste when you take it, as well.” But mint may not appeal to everyone, and if you prefer a flavorless capsule, we recommend Nutricost’s probiotic complex.

Our tester rated the side effects of Ritual’s Synbiotic+ as a 3 out of 5, including the aftertaste as a notable side effect from taking this pill. She experienced “no discomfort after taking it, but looking at the reviews, it seems like some people had temporary side effects. After consistent use, it goes away,” she said, so we recommend being cautious during the first month of adding this supplement to your routine. If you have any concerns, it’s always best to consult a medical professional.

Best Probiotic for Women Over 50: Nutricost Probiotic Complex

Our Thoughts on Nutricost Probiotic Complex

We chose Nutricost’s Probiotic Complex Capsules as our pick for the best probiotic for women over 50; it includes several probiotic needs that help support women throughout and after menopause. 

Lactobacillus rhamnosus, for one, can help maintain a healthy vaginal microbiome and strengthens immune defenses, which is especially important for women after menopause. At this stage, hormonal changes can increase the risk of UTIs, yeast infections, and bacterial vaginosis. Research shows it may lower the likelihood of these common infections by helping restore optimal microbial balance, supporting the body’s natural protective barriers.

Pete, our tester, rated Nutricost’s supplement a 5 out of 5 for his first impression. He appreciated the bottle’s simple open-and-close design and found the label clear and easy to read. The clean layout and compact, travel-friendly size also stood out, making it convenient to take anywhere. He gave the instructions another 5 out of 5, noting their clarity—just take one capsule with a glass of water.

If you’re planning to purchase this probiotic, Pete recommends choosing one of the higher potency CFU options available. “Probiotic bacteria that are associated with a healthy gut flora have a combined dosage of greater than 50 billion CFUs,” he said. “This is generally a good sign for probiotics, though high CFU numbers don’t always correlate with the quality of the products. If you’re taking a probiotic to help with gut health, it’s generally recommended to have at least ten billion CFUs.”

Our tester described the capsules as average in size, roughly a quarter and about half a centimeter wide. He rated them a 3 out of 5, noting they were easy to swallow and had no noticeable taste. After trying Nutricost’s Probiotic Complex, he reported no side effects or digestive issues, earning it a perfect 5 out of 5 in that category.

Best Prenatal Probiotic for Women: Perelel Third Trimester Prenatal Pack

Our Thoughts on Perelel Third Trimester Prenatal Pack

Perelel Third Trimester Prenatal Pack is our pick for the best probiotic for women who are expecting. Perelel offers trimester-specific packs to support your nutrition and overall health, as well as including a probiotic throughout your pregnancy. We recommend talking with your doctor or Ob/Gyn before adding it to your routine. 

Kayla tested this probiotic, rating it a 5 out of 5 for first impressions: “The packaging is really cute and it has a clean aesthetic.” She loves the purple branding, and it exudes safety and quality, which is of utmost significance when taking a supplement while pregnant. “It has a clean label purity aware certification on the box, and some other helpful insights. For example, there is a QR code you can scan which shows you which pill is which.” The QR code provides more information about each capsule, its ingredients, and what it does. Kayla also found the infographic and text helpful in breaking down the entire list of ingredients, why they’re helpful, and how they’re clinically backed.

She also found the instructions easy to follow, rating them a 5 out of 5 in this category. “On the individual packets, it has instructions which state to take with water and food. I really like how this information is listed on the individual packets instead of the main box,” Kayla said. This makes the packets easy to pack for travel, and that way, you don’t have to remember the instructions.

Our tester found the prenatal pack pills easy to take, rating them a 3 out of 5 for swallowability. “There are four pills that look standard in size and shape, then one that is a small pill in the form of a round, liquid capsule. I took them all together at one time, and they were easy to swallow,” Kayla said. She did notice that there was a “slight bitterness” when taking the pills. “It wasn’t too overwhelming,” Kayla said, “but it did have a flavor to it. I would say it tasted more like a multivitamin then a probiotic.”

Despite the slight bitterness, our tester didn’t experience any strange aftertaste or noticeable side effects. Though, since these do come in a larger serving, we recommend having some water or food handy. Overall, Kayla said, “This packet seems like a great all-in-one on the go option for pregnant women or mothers looking to get some extra vitamins into their diet. I like how this is all encompassing with a multivitamin and probiotic.”

Best Probiotic for Women for Bloating: Onnit Total Gut Health

Our Thoughts on Onnit Total Gut Health

Onnit Total Gut Health is our top pick to help reduce bloating because it combines digestive enzymes that break down food, probiotics and prebiotics that support a balanced gut microbiome, and betaine HCl to increase stomach acid production for better digestion. These ingredients work together to promote healthy gut flora, making your digestion more efficient and less prone to gas or bloating.

Kayla described Onnit as a “robust probiotic supplement offered at a relatively affordable price.” Its formula includes seven probiotic strains that provide 10 billion CFUs per serving, along with 500 milligrams of betaine hydrochloride, which may help increase stomach acid levels and promote healthy digestion.

Kayla tried Onnit’s probiotic and gave it a strong first impression, rating it a 5 out of 5. She liked the convenient packaging, which includes fifteen pre-portioned pouches, each with seven capsules ready to take. While she found the amount of information on the box a bit overwhelming, she acknowledged that it clearly explains the product and its benefits.

Our tester wasn’t a fan of taking all the pills required for a serving size of this one, rating it only a 1 out of 5 for ease of swallowing the pills. “Seven capsules are a lot of pills to take all at once. I had to break it up in groups of two, and then take the last pill on its own,” Kayla said. “I took the pills with a large meal as suggested by the product instructions.” For those who prefer a smaller dose, we recommend Ritual Synbiotic+. 

She rated the taste of Onnit’s probiotic as a 3 out of 5, saying: “The pills themselves did not have a taste to them, but they did have a slight smell, like gelatin. There was no aftertaste, either.”

Best Probiotic for Women for Weight Loss: Ora Organic Trust Your Gut

Our Thoughts on Ora Organic Trust Your Gut

We chose Ora Organic Trust Your Gut for weight loss, thanks to its inclusion of pre- and probiotics.   It’s formulated to optimize digestion and reduce bloating, which can support overall better gut health and regularity. Though this product won’t necessarily help you lose weight on its own, by addressing digestive issues, it may make sticking to healthy habits, exercise, and a balanced diet easier for women focused on weight management. 

Thanks to its clean and classy design, Ora Organic earned a 5 out of 5 for first impression. Our tester Kate liked the glass bottle and the easy-to-read label. The instructions were simple to understand, earning this product a 5 out of 5 for ease of use, too.

“I didn’t feel any side effects after taking this probiotic,” Kate said. “There was no weird aftertaste, and I didn’t experience any digestive side effects either.” She liked that there was no taste when taking the pills or afterwards. After reading some reviews, Kate did notice that some folks experienced temporary side effects. If you’re concerned about any potential risks, its best to consult your doctor in advance.

Our tester described these probiotics as “clear vegan capsules with a white interior,” noting that they are an average pill size. She rated ease of swallowing a 3 out of 5, saying, “you only need to take two a day. This isn’t an intimidating pill by any means, though some other products do only require one pill, which may be more convenient for folks who take many supplements. 

Overall, Kate says, “This is a good, affordable probiotic for people who are looking for something they can take every day for digestive support.”

Best Probiotic for Women for Vaginal Health: O-Positiv Vaginal Probiotic

Our Thoughts on O-Positiv Vaginal Probiotic

O-Positiv Vaginal Probiotic is our top pick for vaginal health due to the four strains of probiotics it includes: Lactobacillus acidophilus, Lactobacillus rhamnosus, Lactobacillus reuteri, and  Lactobacillus fermentum. These strains, taken alone or combined, may help restore healthy vaginal flora, maintain ideal vaginal pH, and combat odor-causing bacteria. 

Kayla gave O-Positiv’s Vaginal Probiotic a 5 out of 5 for her first impression. She described the packaging as stylish and eye-catching, with pink branding and modern fonts. The small, matte-finish plastic container makes it travel-friendly and easy to slip into a bag. However, Kayla felt the product name could be confusing, as it might give the impression of a suppository rather than an oral capsule.

Another tester on our team, Gwen, has taken O-Positiv for nearly a year. She loves that Amazon allows you to subscribe to monthly deliveries, so it arrives on her doorstep as soon as she finishes a container.

“I have been taking this probiotic consistently for about a year and I definitely think it’s worthwhile. I’m an athlete who spends long periods of time in sweaty gym clothes,” she says. “You can probably deduce that I experience some personal discomfort, but I have noticed this decrease after consistently taking O-Positiv.” As with other probiotics, it’s unlikely that you’ll experience immediate benefits. However, with consistent use, according to Gwen, you may see some benefit. 

That said, if you’re experiencing any reproductive health conditions or concerns, it’s best to talk to a gynecologist or OB-GYN in advance. Probiotics can be helpful, but they likely won’t solve any existing health issues you’re dealing with.

Kayla rated this probiotic as a 3 for being easy to swallow, saying, “The pills seem to be standard sized, and even with two pills as the serving size, it’s very manageable.” Kayla noted that the pill is a capsule, and the powder inside is pink in color. “Even the pills themselves seem to go with the girly pink aesthetic,” she says. “I could take the serving size without water if I needed to.” These are a great option for folks who may have difficulty swallowing pills.

Kayla rated the side effects of O-Positiv’s Vaginal Probiotic as a 5, as she experienced no side effects from taking these capsules. Overall, Kayla likes that this product has a 60-day money back guarantee and finds the price point to be solid. 

Other Probiotics We Tested

We tested many probiotics for women, but not all of them made our list. Here are some other probiotics we evaluated, and why we didn’t include them:

• Nutricost Probiotic for Women: Our tester didn’t have any standout comments on this probiotic; and in our evaluation, it didn’t seem to offer any special ingredients or benefits to women.

How We Tested and Selected the Best Probiotics for Women

We tested and evaluated the probiotics and scored them on a scale of 1-5 for factors such as first impressions, swallowability, formula, third-party testing, and price per serving. Our testers evaluate the products based on their own individual experiences and preferences. We then review their testing feedback and data to share our findings and recommendations with you.

Formula

We work with a certified nutrition coach during testing to find the most effective and safely formulated probiotic supplements. We look for probiotics that clearly list the specific strain of bacteria on their labeling, since different strains provide different benefits. We also check that the probiotics have at least 10 billion colony-forming units (CFUs) per serving.

Swallowability

When testing and selecting probiotics, we also check the ease of swallowing the supplements. Many adults have difficulty swallowing pills, which may lead to skipping doses or quitting your daily supplement routine. A probiotic that’s easier to swallow can mean better consistency, ensuring that you get the full gut-health benefits from the product.

Third-Party Testing

Third-party testing provides independent confirmation of a supplement’s safety, purity, and accurate labeling. This process helps ensure ingredients are listed correctly, dosages are as claimed, and products are free from harmful substances like heavy metals and pesticides. Since the FDA does not regulate dietary supplements before they reach the market, relying on independent testing is essential to verify quality and protect health.

Value

When considering value, we place a premium on brands that source their ingredients in America and have certifications, such as Informed Choice.

How to Find the Best Probiotics for You

People choose probiotics for a variety of reasons, such as personal wellness goals, dietary requirements, allergies, or specific health conditions they want to manage.

When picking the right probiotic for your needs, consider factors like your health objectives, any dietary restrictions, and sensitivities to ingredients.

Your Body’s Needs

Probiotics are not all created equal; their effects depend on the specific strain used. Individual responses can vary based on factors like body type, immune health, digestive environment, genetics, and sex. To get the best results, consider the health condition you want to address and select a probiotic strain that matches your specific dietary needs and wellness goals.

Common symptoms

• Abdominal pain and bloating: Lactobacillus plantarum 299v, Bacillus coagulans LBSC
• Diarrhea: Saccharomyces boulardii, Bifidobacterium animalis subsp. lactis BB-12 
• Constipation: Lactobacillus acidophilus, Bifidobacterium bifidum

Formula

We recommend talking with your doctor about the best probiotic for you. Since probiotics can vary by strains included, your doctor or gastroenterologist can help with suggestions on the best kind for your dietary needs, health goals, and conditions you are managing.

Cost

Supplements can be costly, so it’s wise to factor in your budget when thinking about adding one to your daily routine. Some probiotic brands require taking several capsules per day, which means you might need to purchase them more often than just every few months, further increasing your overall expense.

Third-Party Testing

Independent third-party testing is essential because the FDA does not directly regulate dietary supplements, including probiotics, before they reach the market. This type of testing provides objective verification of a product’s safety, purity, and label accuracy, helping to prevent problems like contamination, mislabeling, or the inclusion of banned substances. As a result, consumers can have greater confidence in the quality and reliability of the supplements they choose.

Benefits of Probiotics for Women’s Health

Taking probiotics can help keep your digestive system balanced, boost immunity, and may even have effects that reach beyond your gut. Here are some of the benefits:

• Improved digestive health: Probiotic supplements containing strains like Lactobacillus and Bifidobacterium help maintain a balanced gut microbiome, supporting regular digestion and reducing common issues such as bloating, constipation, and diarrhea in women.

• Vaginal health: A healthy vaginal microbiome is key for preventing infections and maintaining overall vaginal health. Recent trials show that daily probiotic supplementation lowers rates of bacterial vaginosis recurrence and supports urinary tract health.

• Immune system support: Women’s immune health is linked to gut and vaginal health. Studies suggest that probiotics, especially Lactobacillus strains, may boost immune cell activity, promote anti-inflammatory responses, and strengthen the body’s defenses against infection and illness.

How to Take Women’s Probiotics

Women’s probiotics can be taken as part of your daily routine, usually with a meal for the best absorption and consistency. While anyone can generally benefit from probiotics, certain women’s health symptoms—such as frequent urinary tract infections (UTIs), recurrent vaginal infections, or frequent digestive distress—shows that probiotic support could be especially helpful. We recommend that you talk with a healthcare professional before starting a new supplement.

Frequently asked questions

What is the number one recommended probiotic for women?

Ritual’s Synbiotic+ stood out as our top choice for women because it contains two of the most well-studied probiotic strains, Lactobacillus rhamnosus and Bifidobacterium animalis ssp. lactis. In addition to its probiotic blend, it also includes prebiotics and postbiotics for comprehensive gut support. This 3-in-1 formula even comes with a subtle mint flavor, making it easy and enjoyable to take.

What are the signs my body needs probiotics?

Signs that you might benefit from using a probiotic include:

• Ongoing digestive problems like bloating, constipation, or diarrhea
• Recent antibiotic use, or diarrhea linked to taking antibiotics
• Frequent infections or a sense that your immune system needs support

Do women’s probiotics actually help?

Probiotics for women can be effective for supporting certain vaginal, urinary, and metabolic health issues, but they may be most beneficial when used for specific reasons as identified by your doctor. We recommend that you talk with your healthcare provider to determine if probiotics are appropriate for your dietary and health needs.