• Home
  • News
  • Fortune 500
  • Tech
  • Finance
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
NewslettersMPW Daily

What to know about Anthropic cofounder Daniela Amodei as the OpenAI competitor races toward profitability

Emma Hinchliffe
By
Emma Hinchliffe
Emma Hinchliffe
Most Powerful Women Editor
Down Arrow Button Icon
Emma Hinchliffe
By
Emma Hinchliffe
Emma Hinchliffe
Most Powerful Women Editor
Down Arrow Button Icon
December 2, 2025, 10:32 AM ET
Jessica Chou for Fortune

On the latest cover of Fortune are a brother and sister: Dario and Daniela Amodei, the cofounders of Anthropic. The OpenAI competitor is now projected to bring in $10 billion in 2025 revenue, with a $183 billion valuation. Notably, its path to profit looks shorter than those of its rivals—with profitability expected in 2028.

Recommended Video

My colleague Jeremy Kahn, Fortune‘s AI editor and author of the book Mastering AI, dives into Anthropic’s business and future in this cover story.

His story also gives us some insight into Daniela herself. As cofounder of Anthropic, she’s one of the most consequential female founders in tech today. Her title is president; she focuses on day-to-day operations and the commercial side of the business, while Dario sets vision, strategy, research and policy.

While Anthropic’s focus on AI safety has been a key distinguisher of its chatbot Claude from its competitors, Daniela’s work commercializing the business is turning out to be a standout factor too. Consumer businesses are in the game of monetizing attention, Dario explains—and the incentives don’t always align to prioritize safety (hence the rise of “AI slop”). Enterprise customers often see safety as a selling point, avoiding problematic outputs like “giving someone instructions for making a bioweapon, revealing company secrets, or spewing hate speech,” Jeremy writes.

Daniela seems to be a cautious leader. “I have probably been the leader who’s been the most skeptical and scared of the rate at which we’re growing,” she told Jeremy. But she says she’s been “continually, pleasantly surprised” that the company hasn’t come apart at the seams, culturally or operationally.

I highly recommend reading Jeremy’s full cover story here.

Emma Hinchliffe
emma.hinchliffe@fortune.com

The Most Powerful Women Daily newsletter is Fortune’s daily briefing for and about the women leading the business world. Subscribe here.

ALSO IN THE HEADLINES

Where Canva's going next. The Sydney-based visual communications company is now valued at $42 billion, the highest valuation for a woman-led and -founded startup in the world. Melanie Perkins and her cofounders chat about the path ahead, including a possible IPO and AI workflows. Inc.

Moms First is setting a record. Reshma Saujani's advocacy organization is producing a new documentary about American motherhood. She tells me it's the "first film that traces the history of American motherhood, from postwar propaganda to the forces that divide us and the cultures that keep us from building solutions." They're gathering thousands of moms to sign on as associate producers—aiming to break a Guinness World Record. 

Disney's succession race is in the home stretch. Dana Walden, TV head, and parks chief Josh D’Amaro are the two final contenders. The board has said it expects to make a decision in early 2026. WSJ

Gretchen Whitmer is Trump's favorite Democrat. The Michigan governor has worked with the president (including a mini scandal when she hid her face in a photo). As Democrats figure out who will lead the party going into the 2028 election, Whitmer and Trump have a "surprisingly productive and affable relationship"—helpful for getting things done, but not always popular with Democratic voters. Politico

ON MY RADAR

The real ways schools are failing boys Time

Influencers made millions pushing 'wild' births—now the Free Birth Society is linked to baby deaths around the world Guardian

Do intimacy coordinators still have a place in Hollywood? Elle

PARTING WORDS

"Live a truthful life, then you don't have any."

— Melinda French Gates on secrets. She's interviewed on the latest episode of Wired's "The Big Interview" podcast. 

This is the web version of MPW Daily, a daily newsletter for and about the world’s most powerful women. Sign up to get it delivered free to your inbox.
About the Author
Emma Hinchliffe
By Emma HinchliffeMost Powerful Women Editor
LinkedIn iconTwitter icon

Emma Hinchliffe is Fortune’s Most Powerful Women editor, overseeing editorial for the longstanding franchise. As a senior writer at Fortune, Emma has covered women in business and gender-lens news across business, politics, and culture. She is the lead author of the Most Powerful Women Daily newsletter (formerly the Broadsheet), Fortune’s daily missive for and about the women leading the business world.

See full bioRight Arrow Button Icon

Latest in Newsletters

NewslettersMPW Daily
What to know about Anthropic cofounder Daniela Amodei as the OpenAI competitor races toward profitability
By Emma HinchliffeDecember 2, 2025
2 minutes ago
NewslettersTerm Sheet
The startup betting AI can unlock a new era of ‘found money’ for enterprises
By Allie GarfinkleDecember 2, 2025
3 hours ago
NewslettersCFO Daily
2026 will be the year of AI monetization, says Wedbush’s Dan Ives
By Sheryl EstradaDecember 2, 2025
4 hours ago
NewslettersCEO Daily
Why smart CEOs are looking past the rosy ‘record Black Friday’ headlines
By Phil WahbaDecember 2, 2025
5 hours ago
Apple CEO Tim Cook (left), Apple SVP of machine learning and AI strategy John Giannandrea (center), and Apple SVP of software engineering Craig Federighi on June 10, 2024 in Cupertino, California. (Photo: Justin Sullivan/Getty Images)
NewslettersFortune Tech
Apple AI chief John Giannandrea heads for the exits
By Andrew NuscaDecember 2, 2025
5 hours ago
NewslettersMPW Daily
Exclusive: Female Founders Fund raises a $29 million fourth fund—a milestone for emerging managers
By Emma HinchliffeDecember 1, 2025
23 hours ago

Most Popular

placeholder alt text
Economy
Ford workers told their CEO 'none of the young people want to work here.' So Jim Farley took a page out of the founder's playbook
By Sasha RogelbergNovember 28, 2025
4 days ago
placeholder alt text
Success
Forget the four-day workweek, Elon Musk predicts you won't have to work at all in ‘less than 20 years'
By Jessica CoacciDecember 1, 2025
22 hours ago
placeholder alt text
Success
Warren Buffett used to give his family $10,000 each at Christmas—but when he saw how fast they were spending it, he started buying them shares instead
By Eleanor PringleDecember 2, 2025
5 hours ago
placeholder alt text
Innovation
Google CEO Sundar Pichai says we’re just a decade away from a new normal of extraterrestrial data centers
By Sasha RogelbergDecember 1, 2025
21 hours ago
placeholder alt text
Big Tech
Elon Musk, fresh off securing a $1 trillion pay package, says philanthropy is 'very hard'
By Sydney LakeDecember 1, 2025
23 hours ago
placeholder alt text
Personal Finance
Current price of gold as of December 1, 2025
By Danny BakstDecember 1, 2025
1 day ago
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • Future 50
  • World’s Most Admired Companies
  • See All Rankings
Sections
  • Finance
  • Leadership
  • Success
  • Tech
  • Asia
  • Europe
  • Environment
  • Fortune Crypto
  • Health
  • Retail
  • Lifestyle
  • Politics
  • Newsletters
  • Magazine
  • Features
  • Commentary
  • Mpw
  • CEO Initiative
  • Conferences
  • Personal Finance
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
About Us
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map

© 2025 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.