• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
Finance

Isis Pharmaceuticals Changes Its Name After Terrorists Attack Stock Price

By
Jen Wieczner
Jen Wieczner
Down Arrow Button Icon
By
Jen Wieczner
Jen Wieczner
Down Arrow Button Icon
December 18, 2015, 5:01 PM ET
Inside of a Gilead Sciences Lab
An automated machine works on purification of potential hepatitis C virus drug candidate at the Gilead Sciences Inc. lab in Foster City, California, U.S., on Wednesday, Feb. 8, 2012. Gilead acquired Pharmasset Inc. last month for its experimental hepatitis C treatments as it aims to compete with other drugmakers like Bristol-Myers Squibb Co. and Merck & Co. to develop a new class of oral cures for hepatitis C to replace older drugs that require injections. Photographer: David Paul Morris/Bloomberg via Getty ImagesPhotograph by David Paul Morris — Bloomberg via Getty Images

Isis Pharmaceuticals announced Friday that it is finally changing its name to something that people won’t confuse with the terrorist group that took credit for the recent Paris attacks and other deadly episodes of violence.

In explaining its decision to change its name to Ionis Pharmaceuticals, the biotech company did not mention terror explicitly. But for the company formerly known as Isis Pharmaceuticals (ISIS) for the past 26 years—whose soon-to-be-changed ticker symbol “ISIS” is identical to the widely used acronym for the Islamic State—the rise of the terrorist network had clearly become a growing problem.

In June 2014, a Wall Street Journal article speculated that an association with negative press about ISIS terrorists might be to blame for a 7% drop in the pharma firm’s stock. Last month after the Paris attacks, CNNMoney raised the possibility that terrorists had again struck Isis Pharmaceuticals’ shares, which fell 4% despite no relevant news. Over the past year, the company’s stock has lost 2.3%, underperforming the Nasdaq Biotechnology Index, which has returned more than 6%, as well as the S&P Pharmaceuticals Select Industry Index, which is just slightly down.

A spokesman for the company dismissed the connection, saying that when it surveyed its institutional investors and stock analysts about whether calling itself Isis was a problem, none had any issue with the name. “We haven’t seen any evidence that our name had any impact on our stock price,” Wade Walke, vice president of communications and investor relations for the Carlsbad, Cali.-based drugmaker, told Fortune. He acknowledged, however, that the company received “lots of calls and emails” from individual retail investors urging it to change its name. “It came down to the point where we were starting to get concerned about the distraction of our name being associated with the terrorist group,” he said.

Even if investors could consciously distinguish between the pharmaceutical company and the terrorists, it’s still possible the confusion could have moved the market. As Fortune detailed in a recent magazine feature, “How Investors Are Using Social Media to Make Money,” in its annual Investor’s Guide, traders are increasingly using algorithms to scan social media and other websites for key terms, triggering computers to buy or sell stocks automatically. But the algorithms aren’t always sophisticated enough to tell the difference between Isis the stock and ISIS the terrorist organization.

Last year, Ionis’s CEO (which was then called Isis) Stanley Crooke told CNBC that sharing the name with terrorists “drives me crazy.” But he also expressed his reluctance to be influenced by the group, adopting a we-don’t-negotiate-with-terrorists sort of attitude. “I don’t feel that I want to capitulate to these terrorists by changing my name,” he said in the interview. “They can change their name.”

Since then, though, the company became concerned that any association with ISIS might pose additional risks to the safety or wellbeing of its employees, particularly if they were traveling, Walke said. He personally experienced the potential problems when he told a local police officer earlier this year that he worked for Isis, whose offices were nearby. The officer responded, “‘You mean the group that cuts people’s heads off?'” Walke recounted. “We want people when they hear or say our name to think about the incredible drugs we’re developing and not a terrorist group.”

While the biotech company’s name was originally chosen more than a quarter-century ago after the Egyptian goddess of health, the company’s new name Ionis doesn’t have any particular significance. The stock will begin trading under ticker symbol “IONS” next week on Dec. 22.

About the Author
By Jen Wieczner
See full bioRight Arrow Button Icon

Latest in Finance

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Fortune Secondary Logo
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • World's Most Admired Companies
  • See All Rankings
  • Lists Calendar
Sections
  • Finance
  • Fortune Crypto
  • Features
  • Leadership
  • Health
  • Commentary
  • Success
  • Retail
  • Mpw
  • Tech
  • Lifestyle
  • CEO Initiative
  • Asia
  • Politics
  • Conferences
  • Europe
  • Newsletters
  • Personal Finance
  • Environment
  • Magazine
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
  • Group Subscriptions
About Us
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Latest in Finance

ExxonMobil CEO Darren Woods, far right, listens as U.S. President Donald Trump,left, speaks during a meeting with oil company executives in the East Room of the White House on Jan. 9. President Trump is aiming to convince oil executives to support his plans in Venezuela, a country whose energy resources he says he expects to control for years to come. US forces seized Venezuelan president Nicolas Maduro in a sweeping military operation on January 3, with Trump making no secret that control of Venezuela's oil was at the heart of his actions.
EnergyIran
Exxon Mobil CEO sees ‘more to come’ on price spikes from Iran war as Exxon, Chevron beat on earnings despite plunging profits
By Jordan BlumMay 1, 2026
37 minutes ago
trump
PoliticsIran
Trump on Iran: ‘They want to make a deal, I’m not satisfied with it, so we’ll see what happens’
By Toqa Ezzidin, Munir Ahmed, Collin Binkley and The Associated PressMay 1, 2026
2 hours ago
infantino
North AmericaWorld Cup
Fifa’s Infantino predicted sellouts and ‘1,000 years of World Cups at once,’ but fans aren’t biting
By James Robson and The Associated PressMay 1, 2026
3 hours ago
cox
C-SuiteWealth
Billionaires have a problem money can’t solve: They don’t know how to talk to their kids
By Nick LichtenbergMay 1, 2026
3 hours ago
trump
EconomyTariffs
Trump says he’ll hike EU auto tariffs to 25%, jolting a world economy that really didn’t need it
By Josh Boak and The Associated PressMay 1, 2026
3 hours ago
male engineer working under pylon
EnergyElectricity
Utility CEOs pocket $626 million as American energy bills hit record highs
By Tristan BoveMay 1, 2026
3 hours ago

Most Popular

China dominates the world's lithium supply. The U.S. just found 328 years' worth in its own backyard
North America
China dominates the world's lithium supply. The U.S. just found 328 years' worth in its own backyard
By Jake AngeloApril 30, 2026
1 day ago
Scott Bessent on financial literacy: 'it drives me crazy' to see young men in blue-collar construction jobs playing the lottery
Personal Finance
Scott Bessent on financial literacy: 'it drives me crazy' to see young men in blue-collar construction jobs playing the lottery
By Fatima Hussein and The Associated PressMay 1, 2026
8 hours ago
The U.S. economy is booming — just not where 50 million Americans live
Commentary
The U.S. economy is booming — just not where 50 million Americans live
By Derek KilmerMay 1, 2026
13 hours ago
Accenture's Julie Sweet blew up 50 years of company history. She says the hardest part is still ahead
Conferences
Accenture's Julie Sweet blew up 50 years of company history. She says the hardest part is still ahead
By Nick LichtenbergApril 29, 2026
2 days ago
Apple cofounder Ronald Wayne—whose stake would be worth up to $400 billion had he not sold it in 1976—says that at 91, he has no regrets
Success
Apple cofounder Ronald Wayne—whose stake would be worth up to $400 billion had he not sold it in 1976—says that at 91, he has no regrets
By Preston ForeApril 27, 2026
4 days ago
Exclusive: America's largest Black-owned bank launches podcast with mission to unlock hidden shame holding back generational wealth
Banking
Exclusive: America's largest Black-owned bank launches podcast with mission to unlock hidden shame holding back generational wealth
By Nick LichtenbergApril 29, 2026
2 days ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.