• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
Leadership

Meet the drug company exec who’s ranked the world’s top CEO

Claire Zillman
By
Claire Zillman
Claire Zillman
Editor, Leadership
Down Arrow Button Icon
Claire Zillman
By
Claire Zillman
Claire Zillman
Editor, Leadership
Down Arrow Button Icon
October 12, 2015, 3:46 PM ET
<h1>16. Lars SØrensen</h1>
<strong>CEO, Novo Nordisk</strong>

Sørensen isn't afraid to take calculated risks: Five years ago he jettisoned the drug maker's diabetes-pill research (while others were pouring money into it), betting instead that injected insulin would continue to be the most effective diabetes treatment. The bet paid off. The pill market shrank because of safety worries and patent expirations, and today Novo Nordisk is the world's biggest insulin producer. Sørensen has positioned the Danish company to keep profiting from the global epidemic: degludec, a new diabetes drug, is close to winning approvals<em>. --</em>OA
<h1>16. Lars SØrensen</h1> <strong>CEO, Novo Nordisk</strong> Sørensen isn't afraid to take calculated risks: Five years ago he jettisoned the drug maker's diabetes-pill research (while others were pouring money into it), betting instead that injected insulin would continue to be the most effective diabetes treatment. The bet paid off. The pill market shrank because of safety worries and patent expirations, and today Novo Nordisk is the world's biggest insulin producer. Sørensen has positioned the Danish company to keep profiting from the global epidemic: degludec, a new diabetes drug, is close to winning approvals<em>. --</em>OAPhoto: John McConnico/Bloomberg/Getty

To find the executive that Harvard Business Review says is the world’s top performing CEO, don’t bother looking in New York or Silicon Valley.

The honoree, Lars Rebien Sørensen, CEO of Danish pharmaceutical company Novo Nordisk, is based in Ridgefield, Connecticut.

The publication placed Sørensen atop its annual list that measures CEOs’ enduring success. Its rankings are based heavily on a company’s long-term financial results and—for the first time this year—take into account its environmental, social, and governance performance as measured by investment research firm Sustainalytics.

Sørensen displaced last year’s No. 1, Jeff Bezos of Amazon (who’s now No. 87 thanks to HBR’s new methodology), in part because his company made the decision to focus almost exclusively on diabetes treatment, which has driven up the company’s sales and stock price. Sørensen also benefited from factors that don’t show up in financial data: Novo Nordisk offers insulin at a steep discount to consumers in developing countries, it has transparent and limited political lobbying practices, and it abides by a what Sustainalytics deems a “responsible” policy on animal testing.

John Chambers, CEO of Cisco Systems is number two on the list. Pablo Isla of Inditex, the Spanish clothing company that owns Zara; Elmar Degenhart of German automotive manufacturing company Continental, and Martin Sorrell of WPP, a marketing services group, round out the list’s top five.

About the Author
Claire Zillman
By Claire ZillmanEditor, Leadership
LinkedIn iconTwitter icon

Claire Zillman is a senior editor at Fortune, overseeing leadership stories. 

See full bioRight Arrow Button Icon

Latest in Leadership

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • Future 50
  • World’s Most Admired Companies
  • See All Rankings
Sections
  • Finance
  • Leadership
  • Success
  • Tech
  • Asia
  • Europe
  • Environment
  • Fortune Crypto
  • Health
  • Retail
  • Lifestyle
  • Politics
  • Newsletters
  • Magazine
  • Features
  • Commentary
  • Mpw
  • CEO Initiative
  • Conferences
  • Personal Finance
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
About Us
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Latest in Leadership

taylor
Politicsphilanthropy
Rural America is getting a bailout, but not from Trump—billionaires are riding to the rescue
By Nick LichtenbergJanuary 14, 2026
7 hours ago
Gates
PoliticsGates Foundation
One year after Bill Gates surprised with the choice to close his foundation by 2045, he’s cutting staff jobs
By Stephanie Beasley and The Associated PressJanuary 14, 2026
8 hours ago
U.S. President Donald Trump (C) walks with Executive chair of Ford Motor Company Bill Ford Jr. (L), and CEO of Ford Motor Company Jim Farley as they tour the Ford River Rouge Complex on January 13, 2026 in Dearborn, Michigan.
Future of WorkTariffs and trade
Trump hails ‘booming investment’ in Detroit while auto manufacturing jobs have fallen every month since Liberation Day
By Eva RoytburgJanuary 14, 2026
9 hours ago
fraser
BankingCitigroup
Citigroup CEO Jane Fraser warns of job cuts and says it’s time to raise the bar in a fiery memo to staff: ‘We are not graded on effort’
By Nick LichtenbergJanuary 14, 2026
11 hours ago
AIHiring
McKinsey challenges graduates to master AI tools as it shifts hiring hunt toward liberal arts majors
By Jake AngeloJanuary 14, 2026
11 hours ago
John Mackey, standing on stage, has his head turned downward with both hands touching his lips.
C-Suitechief executive officer (CEO)
Whole Foods cofounder says his hardest ever business decision was firing his father from his company board: ‘That was when my mentorship was over’
By Sasha RogelbergJanuary 14, 2026
11 hours ago

Most Popular

placeholder alt text
Personal Finance
Peter Thiel makes his biggest donation in years to help defeat California’s billionaire wealth tax
By Nick LichtenbergJanuary 14, 2026
12 hours ago
placeholder alt text
Success
Despite his $2.6 billion net worth, MrBeast says he’s having to borrow cash and doesn’t even have enough money in his bank account to buy McDonald’s
By Emma BurleighJanuary 13, 2026
2 days ago
placeholder alt text
AI
'Godfather of AI' says the technology will create massive unemployment and send profits soaring — 'that is the capitalist system'
By Jason MaJanuary 12, 2026
2 days ago
placeholder alt text
AI
Being mean to ChatGPT can boost its accuracy, but scientists warn you may regret it
By Marco Quiroz-GutierrezJanuary 13, 2026
1 day ago
placeholder alt text
Future of Work
'Microshifting,' an extreme form of hybrid working that breaks work into short, non-continuous blocks, is on the rise
By Nick LichtenbergJanuary 13, 2026
1 day ago
placeholder alt text
Economy
Americans making more than $100,000 are quickly losing faith in the economy—and it's a red flag for the white-collar job market
By Tristan BoveJanuary 12, 2026
2 days ago

© 2025 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.