• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
The Fortune Entrepreneur

Health care startups are booming. Here’s what it takes to succeed

By
Laura Lorenzetti
Laura Lorenzetti
Down Arrow Button Icon
By
Laura Lorenzetti
Laura Lorenzetti
Down Arrow Button Icon
February 19, 2015, 3:14 PM ET
LONDON, ENGLAND - DECEMBER 04: A stethoscope is pictured in a General Practitioners surgery on December 4, 2014 in London, England. Ahead of next years general election, the Chancellor of the Exchequer, George Osborne, has said he will put an extra �2bn into frontline health services across the UK, ahead of a plan drawn up by NHS bosses calling for an extra �8bn a year by 2020. In England, everyone would be able to see a GP seven days a week by 2020. (Photo by Carl Court/Getty Images)
LONDON, ENGLAND - DECEMBER 04: A stethoscope is pictured in a General Practitioners surgery on December 4, 2014 in London, England. Ahead of next years general election, the Chancellor of the Exchequer, George Osborne, has said he will put an extra �2bn into frontline health services across the UK, ahead of a plan drawn up by NHS bosses calling for an extra �8bn a year by 2020. In England, everyone would be able to see a GP seven days a week by 2020. (Photo by Carl Court/Getty Images)Photograph by Carl Court — Getty Images

Health care startups have boomed over the last several years, as evidenced by the number of venture funding deals, which grew some 200% between 2010 and 2014. The boom is driven by health reforms that are disrupting business models, an aging population that’s demanding more (and better) care, and the adoption of technology — such as wearables and video chat — into the medical mainstream.

Add to that boom the fact that it’s a golden age for entrepreneurship, where the declining cost of technology means more entrepreneurs than ever have the tools to build new companies, and you have all the ingredients for a startup revolution in health care.

Last year was dubbed “The Year Digital Health Broke Out” by Startup Health, a leading New York City-based accelerator and networking platform. It was a record year for funding: $6.5 billion was invested in new healthcare ventures, a 125% increase over 2013.

“The health care industry continues to be one of the biggest opportunities for entrepreneurs and investors,” said Bob Kocher, a doctor and partner at Venrock, where he focuses on healthcare IT. “Over-employment and declining productivity has plagued our health care system for decades, but today market forces are driving new incentives and paving the way for disruption.”

That’s where Startup Health comes in. It was founded by longtime business partners Steven Krein and Unity Stoakes. The two men have worked together since 1997, first launching and selling a startup, and then coaching entrepreneurs. They saw the macro trends that were shaping the health care world and knew the industry was ready for a transformation.

They launched Startup Health in 2011 with the mission to help 1,000 startups re-imagine and transform health care over the next decade. To date, they have 90 companies in their portfolio, and three of those startups have already been acquired by the likes of WebMD and Intel.

“We believe we can transform healthcare by supporting the entrepreneurs,” said Stoakes. Health care entrepreneurs have needs that are different to those of other entrepreneurs; their challenges are unique. There’s regulation and entrenched stakeholders. The lead times are longer. You have to play within the system, and that means there are a lot more challenges when it comes to succeeding as a startup in the health care space.

Here, Stoakes and Krein offer advice for what it takes to make it as a startup in the industry.
[fortune-brightcove videoid=3977920542001]

1. Plug into the ‘batteries included’ crowd.

“There are two camps: those that are startup friendly, batteries included, energy-providing, idea-providing, helping the entrepreneurs figure out how to get their ideas — or product or prototype — to the market,” said Krein. “Then there’s a whole camp of resisters; people that are ‘batteries not included.’ They take away all of the momentum of the ideas or concepts of the companies.”

The objective is to connect with more of these “batteries-included” people and organizations to build momentum. Find sources that are startup friendly and willing to lean-in with you — that’s where you should be putting your resources, said Krein.

2. Learn to embrace regulation.

From the Food and Drug Administration’s rules to the Affordable Care Act, health care comes with a host of regulations. It’s an industry full of rules, but rules can be an entrepreneur’s friend.

“A lot of people get spooked by the concept of regulation, but the reality is it’s just a process to work through. And if you know how to work through that process, it’s not that difficult,” said Stoakes. “It can be a competitive advantage.”
[fortune-brightcove videoid=3957338558001]

3. Play with the big dogs.

Healthcare is an industry of established giants: hospital systems, regulators, insurers, and drugmakers. There’s no way to go around these big guys — every entrepreneur needs to work with them.

“In the tech landscape, the idea is that you completely disintermediate — or go around — the established players. So, if you’re Facebook (FB), Twitter (TWTR) or Whatsapp, you don’t even think about the industry stakeholders. In healthcare, the large stakeholders are so important,” said Stoakes. “You really need to be working with these corporate and government partners in order to speed up what’s actually possible.”

4. Settle in for a long slog.

“You can go to places like Silicon Valley and there’s these short-term bootcamps where you hear stories like ‘Slack grew from zero to a billion dollars in nine months,’” said Stoakes. “In healthcare, the sales cycles are very long, and regulatory hurdles can take significant time and the resistance to change is high, so the entire cycle is elongated.”

“There’s an intense amount of patience needed to be an entrepreneur in general, and in health care even more so,” Krein said. “You need to think of it as a five to 10 year minimum kind of initiative. You might get lucky, you might get taken out, you might IPO, but the reality is that it’s going to take a long time.”

5. It’s all about the network.

When it all comes down to it, Stoakes and Krein name two key elements that make a successful health care entrepreneur: being collaborative and coachable.

“It’s impossible to know everything, and you need to be open to being coached. Be open to other experts, ideas and suggestions. Listen really well at every stage,” Krein said. “It’s very difficult to be a rugged individualist in this sector, in particular. It helps to be part of an army of entrepreneurs working together.”

About the Author
By Laura Lorenzetti
See full bioRight Arrow Button Icon

Latest in

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Fortune Secondary Logo
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • Future 50
  • World’s Most Admired Companies
  • See All Rankings
Sections
  • Finance
  • Fortune Crypto
  • Features
  • Leadership
  • Health
  • Commentary
  • Success
  • Retail
  • Mpw
  • Tech
  • Lifestyle
  • CEO Initiative
  • Asia
  • Politics
  • Conferences
  • Europe
  • Newsletters
  • Personal Finance
  • Environment
  • Magazine
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
About Us
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
Fortune Secondary Logo
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Latest in

woman looking stressed paying bills
FinanceGen Z
Gen Z can’t afford the American Dream—so they’ve traded homeownership for paying off debt. ‘Their debt feels heavier because it hits earlier’
By Sydney LakeMarch 1, 2026
1 minute ago
EnergyOil
Oil prices soar 10% as tanker traffic halts near the Strait of Hormuz amid Iran attacks while IRGC warns against passage. ‘Our ships will stay put’
By Jason MaMarch 1, 2026
5 minutes ago
trump
PoliticsWhite House
Trump said ‘we must abandon the failed policy of nation building and regime change’ in 2016. So what changed?
By Tim Sullivan and The Associated PressMarch 1, 2026
11 minutes ago
khamenei
Middle EastMiddle East
Weeks before his death, Iran’s 86-year-old Supreme Leader heard shouts of ‘Death to Khamenei’ and unleashed a bloody crackdown
By Lee Keath, Cara Anna and The Associated PressMarch 1, 2026
16 minutes ago
Big TechSocial Media
YouTube’s cofounder and former tech boss doesn’t want his kids to watch short videos, warning short-form content ‘equates to shorter attention spans’
By Marco Quiroz-GutierrezMarch 1, 2026
27 minutes ago
Slack cofounder Stewart Butterfield
SuccessProductivity
Slack cofounder says workers and CEOs can get stuck doing ‘fake’ work like pre-meetings and slide shows
By Emma BurleighMarch 1, 2026
33 minutes ago

Most Popular

placeholder alt text
Middle East
Iran is now on 'death ground' amid existential threat from U.S. attacks and could 'go big' in retaliation, former NATO commander warns
By Jason MaFebruary 28, 2026
23 hours ago
placeholder alt text
Success
Japanese companies are paying older workers to sit by a window and do nothing—while Western CEOs demand super-AI productivity just to keep your job
By Orianna Rosa RoyleFebruary 27, 2026
2 days ago
placeholder alt text
AI
The week the AI scare turned real and America realized maybe it isn't ready for what's coming
By Nick LichtenbergFebruary 28, 2026
1 day ago
placeholder alt text
Success
Walmart exec says U.S. workforces needs to take inspiration from China where ‘5 year-olds are learning DeepSeek’
By Preston ForeFebruary 27, 2026
2 days ago
placeholder alt text
Personal Finance
Current price of gold as of February 27, 2026
By Danny BakstFebruary 27, 2026
2 days ago
placeholder alt text
Middle East
Dubai’s worst nightmare unfolds as Iran strikes Gulf neighbors
By Dana Khraiche, Fiona MacDonald and BloombergFebruary 28, 2026
19 hours ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.