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Go in depth with the business world’s boldest and brightest. Learn how the most powerful executives navigate the highs and lows of their dynamic roles. Explore past editions of the Fortune 500: Titans and Disruptors of Industry vodcast and CEO Daily newsletter below.

Fortune 500: Titans and Disruptors of Industry

Hosted by Fortune Editor-in-Chief, Alyson Shontell, Fortune 500: Titans and Disruptors of Industry goes in depth with the powerful thought leaders shaping both the world of business and the very way we live.

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46:06

Sam Altman: Safety Standards 'Not at a Place' to Push AI Capabilities Much FurtherSeptember 11, 2026

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44:15

Why GM's CEO Mary Barra is Still Bullish on Electric VehiclesSeptember 9, 2026

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60:32

Bill Ackman's takes on Mamdani, Trump and investing in the age of AIAugust 4, 2026

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47:13

FedEx CEO on How AI Can Fix a $1.8 Trillion Global Supply Chain ProblemJuly 14, 2026

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55:39

$4 Trillion Savings Gap: TIAA’s CEO on The Retirement Crisis June 16, 2026

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49:12

Qualcomm's AI takeover | Titans and DisruptorsMay 5, 2026

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43:48

Delta: Bankrupt to Billions | Titans and DisruptorsMarch 31, 2026

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37:04

The End of Work: Vinod Khosla's Bold AI Prediction | Titans and DisruptorsMarch 3, 2026

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29:19

Google’s AI boss made OpenAI issue code red. Now he wants to solve disease. | Titans and DisruptorsFebruary 10, 2026

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48:34

Pfizer CEO took on COVID. Now he wants to cure cancer | Titans and DisruptorsJanuary 27, 2026

More CEO Conversations

The U.S. needs 1.7 million skilled trades workers a year. Ford wants to help train them

The U.S. needs 1.7 million skilled trades workers a year. Ford wants to help train them

By Diane BradySeptember 30, 2026

Inside Danny Meyer’s promote-from-within culture: 80% of his GMs started as hourly staff

Inside Danny Meyer’s promote-from-within culture: 80% of his GMs started as hourly staff

By Diane BradySeptember 29, 2026

Why the U.S.-China thaw is harder than it looks

Why the U.S.-China thaw is harder than it looks

By Diane BradySeptember 28, 2026

Upstart sports leagues fail constantly. SailGP is beating the odds

Upstart sports leagues fail constantly. SailGP is beating the odds

By Diane BradySeptember 25, 2026

A $499 checkup gave me a peek at the future of AI-powered health care

A $499 checkup gave me a peek at the future of AI-powered health care

By Diane BradySeptember 24, 2026

Retail CEOs see a holiday paradox: shoppers are anxious but still willing to spend

Retail CEOs see a holiday paradox: shoppers are anxious but still willing to spend

By Phil WahbaSeptember 23, 2026

The AI race should be less about supremacy and more about sustainability

The AI race should be less about supremacy and more about sustainability

By Diane BradySeptember 22, 2026

The midterms are a stress test for American media

The midterms are a stress test for American media

By Diane BradySeptember 21, 2026

Bots now outnumber human traffic on the web. Cloudflare’s CEO wants AI companies to pay for it

Bots now outnumber human traffic on the web. Cloudflare’s CEO wants AI companies to pay for it

By Diane BradySeptember 18, 2026

Europe’s CEOs are ready to turn its energy challenge into a competitive edge

Europe’s CEOs are ready to turn its energy challenge into a competitive edge

By Kirsty McGregorSeptember 17, 2026

Mary Barra

GM CEO Mary Barra says America has a ‘societal problem’ with skilled trades—and is putting $200 million behind training Gen Z to work with their hands

By Preston ForeSeptember 17, 2026

CEOs are still betting on the leadership trait AI can’t replace

CEOs are still betting on the leadership trait AI can’t replace

By Diane BradySeptember 16, 2026

Sam Altman on the burden of leading OpenAI amid AI safety concerns: ‘You get used to anything’

Sam Altman on the burden of leading OpenAI amid AI safety concerns: ‘You get used to anything’

By Fortune EditorsSeptember 15, 2026

CEOs warn against falling into AI’s efficiency trap: The biggest risk is ‘a better version of yesterday’

CEOs warn against falling into AI’s efficiency trap: The biggest risk is ‘a better version of yesterday’

By Lee WilliamsonSeptember 15, 2026

OpenAI’s Sam Altman says Paul Graham’s Y Combinator taught him how to govern, not rule: ‘We won’t get every decision right’

OpenAI’s Sam Altman says Paul Graham’s Y Combinator taught him how to govern, not rule: ‘We won’t get every decision right’

By Tatiana SatauaSeptember 14, 2026

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Most Popular

Mike Rowe on America’s great tradesperson shortage: ‘I don’t care what your politics are. Math doesn’t care, either’

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By Nick LichtenbergSeptember 30, 2026

Jeff Bezos is giving $25 million to protect the Pacific—but his climate fund still has about $7 billion left to spend in four years

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By Sydney LakeSeptember 30, 2026

Palantir CEO Alex Karp quietly purchased 37,000 acres of forests in Sweden—and locals found out when hunters lost leases to use the property

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By Sasha RogelbergSeptember 30, 2026

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