Next to Lead: The 25 Most Powerful Rising Executives in the Fortune 500

Leadership transitions in the Fortune 500 carry heightened significance as companies confront geopolitical volatility, economic pressure, and rapid technological change. Today’s boards aren’t just seeking steady operators; they need leaders who can navigate uncertainty, drive transformation, deliver sustained growth, and harness emerging technologies at scale.

The second Fortune Next to Lead list recognizes 25 influential executives who embody that shift. They run major businesses, shape enterprise strategy, and deliver results in environments defined by constant disruption. Each is already operating with CEO-level command, and together, they signal what the next wave of Fortune 500 leadership could look like.