In April 2018, Cairns was promoted to vice chair of Mastercard, the financial services company with $12.5 billion in revenue. Cairns, also a member of the global management committee, had spent the previous seven years as president of Mastercard’s international division, a role that put in her charge of 60% of the company’s global revenue. Her new role gives her strategic oversight of global projects at Mastercard, including those involving inclusion, diversity, and innovation.