Align Technology

Almost $20 trillion in revenue—and a record-breaking $1.87 trillion in profits. Introducing the 2025 Fortune 500, the definitive list of the biggest companies in America.

Fortune 500

The Fortune 500, in its 70th year in 2024, ranks the biggest U.S. companies by revenue.

The 200 companies on this list are transforming industries from the inside out.

America's Most Innovative Companies

The Fortune 500, in its 69th year in 2023, ranks the biggest U.S. companies by revenue.

This year’s Fortune 500 marks the 68th running of the list.

Resilience and the capacity for reinvention have never been more important.

FGC 2021-Align Technology

The Future 50

This year’s Fortune 500 marks the 67th running of the list.

Collectively, the ranked companies produced a three-year average shareholder return of 33%, vs. 19% for the S&P 500.

100 Fastest-Growing Companies

Explore this year's ranking of the 50 companies with the best long-term growth potential.

The pandemic initially caused a lot of frowns at medical-device maker Align Technology as dentists’ offices around the globe temporarily shut down. But by October, the company was reporting record sales of its 3D scanners, which are used by dentists and orthodontists, as well as the company’s popular Invisalign clear plastic teeth straighteners. Third-quarter sales were up 21% over the year earlier. Align has long dominated the clear-aligners market with Invisalign, which is increasingly challenging the hegemony of traditional metal braces. Now Align is seeking to fend off competitors with high-profile endorsements from teen influencers, including TikTok superstar <a href="https://fortune.com/40-under-40/2020/charli-damelio/">Charli D’Amelio</a> and <em>Black-ish</em> actor Marsai Martin.

This year's Fortune 500 marks the 66th running of the list.

This year's Fortune 500 marks the 65th running of the list.

Everybody loves an up-and-comer: 2019's top three-year performers in revenues, profits, and stock returns.

Everybody loves an up-and-comer: 2018's top three-year performers in revenues, profits, and stock returns.

Everybody loves an up-and-comer: 2017's top three-year performers in revenues, profits, and stock returns.

Fastest-growing Companies

Revenue 3 Yr Growth Rank

Revenue 3 Yr Annual Growth Rate

EPS 3 Yr Growth Rank

EPS 3 Yr Annual Growth Rate

Total Return 3 Yr Rank

Total Return 3 Yr Annual Rate

Beat S&P 500 3 Yr Return

Current Streak

Years on List

Sector

Future 50

Overall Score

Culture rank

Process rank

Product rank

Key Financials (last Fiscal Year)

Revenues ($M)

Profits ($M)

Assets ($M)

Total Stockholder Equity ($M)

Profit Ratios

Profit as % of Revenues

Profits as % of Assets

Profits as % of Stockholder Equity

Earnings Per Share (last Fiscal Year)

Earnings Per Share ($)

EPS % Change (from prior fiscal year)

EPS % Change (5 year annual rate)

EPS % Change (10 year annual rate)

Total Return

Total Return to Investors (last year)

Total Return to Investors (5 year, annualized)

Total Return to Investors (10 year, annualized)

Get insights into Align Technology including business profile, stock information, news, and rankings from Fortune.

Align Technology

Align Technology in Fortune Rankings

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