The Best Probiotics for Men: Expert Researched and Tested

For today’s leaders, gut health isn’t just wellness—it’s a performance strategy that fuels sharper decisions and sustained energy under pressure. If you’re looking to boost your immunity or reduce chronic digestive symptoms by taking a daily probiotic supplement, selecting the right probiotic can make a real difference in how you feel. 

We worked with a certified nutrition coach to test and evaluate the best probiotic supplements of 2025 for men. Maintaining a healthy gut may even help improve productivity and well-being at work—with research showing that fewer sick days and better digestive comfort can contribute to a sharper, more energetic presence in the business world.

Why Trust Fortune

Our team of expert testers has tried hundreds of the most popular supplements on the market today, using our comprehensive supplement testing methodology to find the best products for all folks.

Best 5 Probiotics for Men of 2025

• Best Probiotic for Men Overall: Ritual Synbiotic+
• Best Probiotic for Weight Loss for Men: Transparent Labs Gut Health
• Best Probiotic for Men for Bloating: Onnit Total Gut Health
• Best Budget Probiotic for Men: Nutricost Probiotic Complex
• Best Probiotic for Men Over 50: Biotics8

Best Probiotics for Men Comparison Table

Best Probiotic for Men Overall: Ritual Synbiotic+

Our Thoughts on Ritual Synbiotic+

Ritual’s Synbiotic+ is our pick for the best overall probiotic for men because of its inclusion of two of the most clinically researched strains: Lactobacillus rhamnosus and Bifidobacterium animalis ssp. lactis, as well as its pre- and post-biotic support. It’s a great 3-in-1 supplement with a hint of mint, making it pleasant to ingest. 

Of the pill itself, our tester Kate says, “It’s a typical double encapsulated pill that’s enterically coated. The coating helps protect the second capsule when traveling through the stomach, so that the second capsule can break down in your body.” She rated the ease of taking the capsule as a 3 out of 5. “The second, inner capsule almost looks like gold flakes that is broken down powder. You need one pill per serving.” We like that a single pill gets the job done, rather than having to swallow multiple pills to get the probiotic effects.

Kate rated Ritual’s Synbiotic+ a 5 out of 5 for her first impression. “I love Ritual’s packaging: it’s a matte, gray bottle with clean and classy font. The font is in white on a light gray background, so it could be hard for some people to read.” She noted that the supplement facts and instructions are clearly labelled and easy to understand. “The bottle is easy to open, and the pills are easy to get out of the bottle. Someone with dexterity issues shouldn’t have too much of a problem opening it,” she said. 

Our tester rated the taste and flavor of this supplement as a 3, saying: “It tastes minty. There is also an overwhelming mint smell when you open the bottle, and there’s a mint aftertaste when you take it, as well.” Kate said the mint flavor is pleasant to her, but if you are considering a probiotic and would prefer to avoid any flavors, we recommend Transparent Labs Gut Health.

Kate rated the side effects of Ritual’s Synbiotic+ as a 3 out of 5, including the aftertaste as a notable side effect from taking this pill. She experienced “no discomfort after taking it,” but also highlighted: “Looking at the reviews, it seems like some people had temporary side effects. After consistent use, it goes away.” So we recommend being cautious during the first month of adding this supplement to your routine. If you have any concerns, though, it’s always best to consult a medical professional.

Best Probiotic for Men for Weight Loss for Men: Transparent Labs Gut Health

Our Thoughts on Transparent Labs Gut Health

Transparent Labs Gut Health is our choice for the best probiotic for men looking to lose weight. Taking a probiotic may help promote a more balanced gut microbiome, which plays an important role in metabolism, appetite, and body fat storage. The strains found in this supplement may help decrease fat absorption, influence the release of appetite-regulating hormones, improve insulin sensitivity, and reduce inflammation—all factors that can contribute to healthy weight management.

Pete, our resident dietitian, tested this probiotic. He rated it a 5 out of 5 for first impressions: “It’s a small white plastic container that’s travel-friendly. The bottle is easy to open and close, and has a white metallic label with blue lettering.”

He rated the directions a 5, finding them easy to follow. Pete emphasized the directions’ clarity and simplicity: “Take two capsules daily with a full glass of water, preferably on an empty stomach, or as directed by a qualified healthcare professional.” When taking the capsules, Pete didn’t notice any taste. “They’re clear capsules with white powder, about the length of a quarter and half a centimeter in width.” However, he did rate the capsules a 3 out of 5 for ease of swallowing, as they can be a little large for some folks.

Pete didn’t experience any side effects after taking Transparent Labs Gut Health probiotic, giving this category a 5 out of 5. Overall, he noted that this product contains a probiotic blend of ten strains of probiotic bacteria. “The combined dose is 100 billion CFU, which is considered a strong probiotic supplement,” he said. “Multi-strain probiotics are generally better than single strain options, as they can have a more robust effect on the gut microbiome.”

Best Probiotic for Men for Bloating: Onnit Total Gut Health

Our Thoughts on Onnit Total Gut Health

Onnit Total Gut Health is our top pick for bloat reduction, as it combines multiple probiotic strains—Lactobacillus acidophilus DDS-1, Lactobacillus plantarum, Lactobacillus rhamnosus, Bifidobacterium infantis, Bifidobacterium lactis, and Saccharomyces boulardii—with digestive enzymes and prebiotics designed to support balanced digestion.

Kayla tested Onnit’s probiotic and had a great first impression, rating it a 5: “I like how it comes in easy-to-take pouches. The box includes fifteen servings of pre-divided small pouches with seven capsules ready to go.” She notes that the packaging has a lot of information on it, so it may be a little overwhelming, but it does a good job of explaining the product and its benefits. 

However, she wasn’t a fan of taking all the pills required for a serving size of this one, rating it only a 1 out of 5 for ease of swallowing the pills. “Seven capsules are a lot of pills to take all at once. I had to break it up in groups of two, and then take the last pill on its own,” Kayla said. “I took the pills with a large meal as suggested by the product instructions.” For those who prefer a smaller dose, we recommend Ritual Synbiotic+. 

Our tester rated the taste of Onnit’s probiotic as a 3 out of 5: “The pills themselves did not have a taste to them, but they did have a slight smell, like gelatin. There was no aftertaste, either,” Kayla said.

Regarding the formulation, Kayla says Onnit is a “robust probiotic supplement that comes at a fairly affordable price point.” Not only does it contain seven strains of probiotics totaling 10 billion CFUs, but it also contains 500 milligrams of betaine hydrochloride, which may help promote stomach acid production, which can aid digestion.

Best Budget Probiotic for Men: Nutricost Probiotic Complex

Our Thoughts on Nutricost Probiotic Complex

Nutricost Probiotic Complex Capsules are our pick for the best budget-friendly option, costing under 50 cents per serving and providing a two-month supply per bottle. Along with the low price, each capsule delivers a blend of 10 different probiotic strains to support gut health—making these capsules a great value for anyone seeking comprehensive digestive support.

Pete tested Nutricost’s probiotics, rating them a 5 out of 5 for first impression. “The bottle is easy to open and close, and the label is easy to read. It’s a white plastic container with a simple white, blue, and orange label. It would be very travel friendly,” he said. Pete also rated the instructions as a 5, finding them simple and easy to follow—take one capsule a day with eight to 12 ounces of water. 

Describing the capsules, Pete wrote, “They’re normal in size, about the length of a quarter and half a centimeter wide.” He rated them a 3 out of 5, considering them easy to swallow. There was no taste to the capsules, he said. He didn’t notice any side effects or digestive issues after testing out Nutricost’s Probiotic Complex, rating it a 5 out of 5 in this category.

If you’re planning to purchase this probiotic, Pete recommends choosing one of the higher potency CFU options available. “Probiotic bacteria that are associated with a healthy gut flora have a combined dosage of greater than 50 billion CFUs. This is generally a good sign for probiotics, though high CFU numbers don’t always correlate with the quality of the products. If you’re taking a probiotic to help with gut health, it’s generally recommended to have at least ten billion CFUs.”

Best Probiotic for Men Over 50: Biotics8

Our Thoughts on Biotics8

Biotics 8 is formulated specifically for men, containing multiple strains of probiotics, prebiotic fibers, Vitamin D, and digestive enzymes. We like the inclusion of both Lactobacillus plantarum and Lactobacillus acidophilus, which help to optimize your gut microbiome, reduce inflammation, and enhance metabolism. The inclusion of Vitamin D may also help to support men’s testosterone production, though more research is needed to create a strong link between the two.  

Pete tested Biotics 8, rating it a 5 out of 5 for first impressions. The product comes in a black plastic container with a matte black label and has orange and white lettering. Our tester described it as travel friendly, easy to open and close, and readable without difficulty.

He found Biotics8 instructions pretty easy to follow, earning them a 3 out of 5 rating in this category. “For adults, it says to take one capsule per day for the first four days. Then for days five to nine, take two capsules per day. Then, after this you take three capsules per day going forward. The gradual introduction allows time for your gut to adjust,” Pete said. We like this initial ramping up phase, finding it helpful to avoid potential side effects. 

Pete didn’t experience any side effects or digestive issues when taking Biotics8, rating it a 5 out of 5 because of this. Of the experience, he noted that the capsules are “small and clear, with white powder. The capsules are relatively small and easy to swallow. There was no taste or aftertaste to them,” he said.

How We Tested and Selected the Best Probiotics for Men

We tested and evaluated probiotics and scored them on a scale of 1-5 for factors such as first impressions, swallowability, formula, third-party testing, and price per serving. Our testers evaluate the products based on their own individual experiences and preferences. We then review their testing feedback and data to share our findings and recommendations with you.

Formula

We work with a registered dietitian (RD) during testing to find the most effective and safely formulated probiotic supplements for men. We look for probiotics that clearly list the specific strain of bacteria on their labeling, since different strains provide different benefits. We also check that the probiotics have at 10 billion colony-forming units (CFUs) per serving. And finally, we prioritized formulas made specially to support men’s health.

Swallowability

When testing and selecting probiotics, we also check the ease of swallowing the supplements. Many adults have difficulty swallowing pills, which may lead to skipping doses or quitting your daily supplement routine. A probiotic that’s easier to swallow can mean better consistency, ensuring that you get the full gut-health benefits from the product.

Third-Party Testing

Third-party testing ensures independent verification of safety, purity, as well as nutrition label accuracy. This helps to reduce the risk of mislabeling or underdosing. Third-party testing also checks for harmful substances such as heavy metals, pesticides, and more for safety. 

The FDA (U.S. Food and Drug Administration) does not regulate supplements, so it’s vital to have independent testing done to ensure safety, accuracy, and quality.

Value

When considering value, we place a premium on brands that source their ingredients in America and have certifications, such as Informed Choice.

How to Find the Best Probiotics for You

Everyone has different reasons for taking a probiotic, depending on your goals, dietary needs, allergies, and any health conditions you manage.  

Here’s what to consider when selecting the best probiotic supplement for you.

Your Body’s Needs

Not all probiotics work the same way; their effects are strain-specific. Your body type, immune system, digestive environment, genetics, and sex can all help determine your response to a particular probiotic strain. To optimize your benefits, choose a probiotic based on the health condition you are managing, along with any dietary needs or goals.

Common Symptoms

• Abdominal pain and bloating: Lactobacillus plantarum 299v, Bacillus coagulans LBSC
• Diarrhea: Saccharomyces boulardii, Bifidobacterium animalis subsp. lactis BB-12 
• Constipation: Lactobacillus acidophilus, Bifidobacterium bifidum

Formula

We recommend talking with your doctor about the best probiotic for you. Since probiotics can vary by strains included, your doctor or gastroenterologist can help with suggestions on the best kind for your dietary needs, health goals, and conditions you are managing.

Cost

Supplements can be expensive, so it’s important to think about your budget when considering adding a new supplement to your daily routine. Some probiotics require you to take multiple capsules per day, which means you may need to buy the probiotics more frequently than once every few months.

Third-Party Testing

Third-party testing independently verifies the safety, purity, and label accuracy of probiotics since the FDA doesn’t regulate supplements. This process helps protect you from mislabeling, contamination, and banned substances, building trust and ensuring you can use products with confidence. Independent testing is essential for confirming product quality and safeguarding your health.

Benefits of Probiotics for Men

Probiotics offer men a wide range of health benefits, supported by research across several key areas. By replenishing beneficial bacteria in the gut, probiotics can strengthen digestive function, metabolic health, immunity, reproductive wellness, and even mental well-being.

• Improved Gut Health: Probiotics help restore and maintain healthy gut bacteria, reducing symptoms like constipation, diarrhea, and bloating.
• Lower Risk of GI Diseases/Issues: Taking probiotics routinely can decrease the likelihood and severity of gastrointestinal conditions such as antibiotic-associated diarrhea and chronic acid reflux.

• Boosted immune function: Probiotics help support the immune system, leading to fewer infections and a balanced inflammatory response.
• Enhanced male reproductive health: Some strains have shown improvements in men’s sperm quality, motility, and testosterone levels. However, it’s best to consult a doctor before purchasing a probiotic for reproductive health, as there are likely better treatment options.

What to Avoid in Probiotics for Men

Here are three things men should avoid when choosing a probiotic supplement:

• Artificial sweeteners or filler ingredients: Many lower-quality probiotics may include artificial colors, sweeteners, or unnecessary fillers, which can trigger allergic reactions or digestive upset.
• Common allergens: Always check the label for common allergens like dairy, gluten, soy, or eggs, especially if you have a known intolerance or allergy, as these can cause adverse reactions and skin issues.
• Low quality or unverified strains: Avoid products without third-party testing or clear strain identification, as these may be contaminated, lack potency, or include unlisted microorganisms that could pose infection risks—especially for those with compromised immune systems.

Frequently asked questions

What is the top rated probiotic for men?

Our team selected Ritual’s Synbiotic+ as our pick for the best overall probiotic for men because of its inclusion of two of the most clinically validated strains: Lactobacillus rhamnosus and Bifidobacterium animalis ssp. lactis, as well as its pre- and post-biotic support. It’s a great 3-in-1 supplement with a hint of mint, making it pleasant to take.

Should males take probiotics?

Men can benefit from taking probiotics, especially for digestive, immune, and metabolic health. Probiotics support a balanced gut environment, reduce symptoms like bloating and irregularity, enhance nutrient absorption, and may help support men’s prostate health and fertility.

What are signs you need a probiotic?

You may benefit from adding a probiotic if you experience any of the following:

• Ongoing digestive concerns like bloating, constipation, or diarrhea.
• Recent or current use of antibiotics, especially if you’re dealing with antibiotic-related diarrhea.
• Frequent infections or a sense that your immune health needs extra support.