Making the Fortune 500 list is no small feat, yet every year a fresh group of companies elbows its way in by displacing incumbents and reshuffling the ranks of American corporate power.
To make it on the list of the top 500 companies in the U.S. by revenue, a company has to meet strict requirements, including a minimum of $7.5 billion in revenue in 2026. This year 12 companies made it on the list for the first time across industries like crypto, mattresses, and natural gas.
Here are the companies making their debut on the Fortune 500 in the list’s 72nd year.
Galaxy Digital
Fortune 500 Rank: 76
Revenue: $61.3 billion
Just over a year after going public through a direct listing in May 2025, Galaxy Digital debuted on the Fortune 500 list at No. 76. The blockchain and digital assets company, which was founded in 2018 by billionaire and former Wall Street hedge fund manager Mike Novogratz, has seized on the increasing institutional adoption of crypto to supercharge its business. The company offers services like market making, asset management, and advisory services for institutional clients.
Medline
Fortune 500 Rank: 159
Revenue: $28.4 billion
This Northfield, Ill.-based company is the largest provider of medical-surgical products in the healthcare industry. The company traces its roots to 1910 when it started as a garment company. In 1966, the modern founders of the company, Jon and Jim Mills, took over and later found success producing medical products like surgical gloves and surgical trays. The company’s IPO was the biggest of 2025, bringing in $6.3 billion following its debut on the NASDAQ.
BitGo Holdings
Fortune 500 Rank: 273
Revenue: $16.1 billion
Founded in 2013, BitGo provides crypto services to institutional customers, including wallet services, staking, trading, and financing. The Palo Alto-headquartered company serves thousands of clients across more than 100 countries and completed its IPO in 2026, claiming a spot as the first major public offering of a crypto company this year.
Amentum Holdings
Fortune 500 Rank: 313
Revenue: $14.4 billion
Spun out of the management services group of AECOM (No. 276), Amentum Holdings went public in 2024 and this year earned its own place on the Fortune 500. The Chantilly, Va. company gets much of its revenue from its work with the federal government as one of the largest U.S. government contractors supporting missions in defense, nuclear security, cybersecurity, environmental remediation, and space.
Venture Global
Fortune 500 Rank: 328
Revenue: $13.8 billion
This Arlington, Va.-based company is a major exporter of liquified natural gas. Some of its notable projects near the Gulf Coast include Plaquemines LNG and CP2 LNG, which together have an export capacity of more than 40 metric tons per year. The company focuses on serving customers in Europe, Asia, and other markets.
Comfort Systems
Fortune 500 Rank: 440
Revenue: $9.1 billion
Comfort Systems provides mechanical, electrical, and plumbing contract services for commercial and industrial buildings. The Houston-based HVAC company has more than 50 subsidiaries in 142 cities in the U.S. Building the modular cooling units used to regulate the temperature of data centers is becoming an increasingly important area of its business. As the AI boom has increased the number of data centers either under construction or planned to nearly 3,000, the company has benefitted. Its stock is up more than 80% year to date.
Arista Networks
Fortune 500 Rank: 444
Revenue: $9 billion
Arista Networks is a Santa Clara, Calif.-based company that specializes in cloud networking platforms that was founded and incorporated in 2008. After 10 years, it entered the S&P 500 and has seen its shares skyrocket more than 500% in the last five years thanks in part to the AI boom. The company provides client-to-cloud networking services for data centers, and its clients include some of the biggest cloud operators and enterprise tech users.
Marvell Technology
Fortune 500 Rank: 476
Revenue: $8.2 billion
Marvell Technology is a semiconductor company that designs custom silicon chips for data infrastructure applications for cloud computing and AI, but also enterprise networking and automotive systems. Founded in 1995 in Santa Clara, Calif, the company later moved its headquarters to Wilmington, Del. After Nvidia CEO Jensen Huang said at a conference this week that Marvell could be “the next trillion-dollar company” the company’s stock shot up 32% in one day. Nvidia in March invested $2 billion in the company.
APi Group
Fortune 500 Rank: 486
Revenue: $7.9 billion
APi group is based in New Brighton, Minn. and focuses on safety and specialty services for the construction industry. It designs, and installs systems to protect workers, including fire sprinkler systems, security and surveillance systems, and access control systems. It also provides other services like infrastructure and utility services. The company has a long history, and dates back to 1926, when it was called the Reuben L. Anderson-Cherne mechanical company. It employs about 29,000 people across 500 locations worldwide.
Primoris Services
Fortune 500 Rank: 497
Revenue: $7.6 billion
Primoris Services provides infrastructure, construction, engineering, and maintenance services for the energy and renewables markets in the U.S. and Canada. The company, which is based in Dallas, has been a key contributor in the clean energy buildout in both countries.
Somnigroup International
Fortune 500 Rank: 499
Revenue: $7.5 billion
Formerly known as Tempur Sealy International, Somnigroup International is the world’s largest bedding company and is the owner of mattress retailers Mattress Firm and U.K.-based Dreams. The company also oversees the well known Tempu-Pedic brand of viscoelastic, or memory foam, mattresses and other products. The company operates more than 2,000 physical retail stores in more than 100 countries.
Resideo Technologies
Fortune 500 Rank: 500
Revenue: $7.5 billion
Resideo Technologies is a Scottsdale, Ariz.-based company that specializes in smart home products and other technology for buildings. Spun off from Honeywell in 2018, the company focuses on systems that distribute temperature, humidity, and water in homes and other buildings.
