• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
China

A city of 650,000 had zero COVID deaths until Sunday. Omicron’s most transmissible subvariant yet finally overtook its defenses

Grady McGregor
By
Grady McGregor
Grady McGregor
Down Arrow Button Icon
Grady McGregor
By
Grady McGregor
Grady McGregor
Down Arrow Button Icon
July 4, 2022, 4:30 AM ET
Police officers stand near a carriage outside a casino in Macau on Oct. 4, 2021. The region is experiencing its biggest-ever COVID outbreak.
Police officers stand near a carriage outside a casino in Macau on Oct. 4, 2021. The region is experiencing its biggest-ever COVID outbreak. Cheong Kam Ka/Xinhua via Getty Images

Macau, a semiautonomous region off the coast of southern China known for its casinos, recorded its first-ever deaths from COVID-19 after two elderly people with underlying conditions—a 100-year-old and a 94-year-old—succumbed to the disease on Sunday. The deaths break Macau’s streak of being one of the only cities on earth to not record a death from COVID-19 since the pandemic broke out two and a half years ago and went on to kill 6.3 million people around the world. Globally, 1,500 people are still dying from COVID-19 daily.

Macau health officials say the new Omicron variant BA.5 is driving the current outbreak. BA.5 has rapidly become the dominant strain in the U.S. and elsewhere due to its high degree of transmissibility. Health experts attribute BA.5’s fitness to its ability to evade vaccine defenses and infect people who have previously caught COVID-19.

Macau recorded its first COVID deaths as it faces its largest-ever outbreak of the virus. The gambling hub of 650,000 people has reported 784 cases since June 18. Before then, it had recorded 151 total in total.

Macau kept COVID at bay by sealing itself off from the rest of the world. The territory deploys strict COVID-zero policies and harsh border restrictions similar to mainland China’s. Macau requires that all travelers entering the city undergo a 10-day hotel quarantine (which the city recently reduced from 14 days). Once inside Macau, residents must use a health code app to enter restaurants, casinos, and shopping malls.

Macau authorities are still not sure how the virus entered the city, but the first clusters in June were traced to an employee at a prison and a worker at a meat shop who often commuted between Macau and the nearby city of Zhuhai in mainland China.

The new outbreak has pushed the city to tighten its restrictions. Macau has allowed casinos to stay open but forced schools to end the academic year early. The city has also shut down bars, cinemas, salons, gyms, government buildings, and in-person dining at restaurants.

Macau is the world’s largest gambling hub. Before the pandemic, it took in five times more gaming-related revenue per year than Las Vegas. But Macau’s COVID restrictions have taken a toll on the city’s economy, with casino revenue down 80% this year compared to pre-COVID levels.

From July 4 to July 9, Macau will test every city resident for COVID-19 three times, Macau’s secretary for social affairs and culture, Elsie Ao Ieong, announced on Sunday. After this round of tests, every Macau resident will have been tested for COVID six times since mid-June; the government just completed a different round of three citywide tests last week.

As Macau battles BA.5, nearby Hong Kong is paying close attention. In recent weeks, Hong Kong authorities have started sending people infected with BA.5 and its cousin BA.4—plus their close contacts—to centralized quarantine facilities even as the government allows people infected with other Omicron subvariants to quarantine at home.

Mainland China also appears to be tightening COVID measures days after it appeared to resume normal life following Shanghai’s months-long lockdown. Over the weekend, China’s government put 1.7 million people in central Anhui province into lockdown after authorities discovered over 1,000 infections in the province. (It is unclear which Omicron subvariant is responsible for the Anhui outbreak.)

For now, it appears there is no end in sight to rounds of lockdowns and mass testing in mainland China, as well as in Hong Kong and Macau, which often follow the central government’s lead.

“Our country has a large population; such strategies as ‘herd immunity’ and ‘lying flat’ would lead to consequences that are unimaginable,” Chinese President Xi Jinping said in Wuhan last week about China’s commitment to its COVID-zero strategy.

Sign up for the Fortune Features email list so you don’t miss our biggest features, exclusive interviews, and investigations.
About the Author
Grady McGregor
By Grady McGregor
LinkedIn iconTwitter icon
See full bioRight Arrow Button Icon

Latest in

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Fortune Secondary Logo
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • World's Most Admired Companies
  • See All Rankings
  • Lists Calendar
Sections
  • Finance
  • Fortune Crypto
  • Features
  • Leadership
  • Health
  • Commentary
  • Success
  • Retail
  • Mpw
  • Tech
  • Lifestyle
  • CEO Initiative
  • Asia
  • Politics
  • Conferences
  • Europe
  • Newsletters
  • Personal Finance
  • Environment
  • Magazine
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
  • Group Subscriptions
About Us
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Latest in

Google Cloud revenue is now 18% of Alphabet’s business. Is this the beginning of the end of Google’s search identity?
Big TechGoogle
Google Cloud revenue is now 18% of Alphabet’s business. Is this the beginning of the end of Google’s search identity?
By Alexei OreskovicApril 29, 2026
5 hours ago
Man wearing a suit and tie and glasses
Big TechTech
Microsoft, Meta, and Google just announced billions more in AI spending. Only Google convinced investors it’s paying off
By Amanda GerutApril 29, 2026
5 hours ago
A man in a suit and tie
InvestingMeta
Meta just bumped its 2026 capex forecast up to as much as $145 billion for the AI boom—and investors flinched
By Amanda GerutApril 29, 2026
7 hours ago
teri
BankingBanks
Exclusive: America’s largest Black-owned bank launches podcast with mission to unlock hidden shame holding back generational wealth
By Nick LichtenbergApril 29, 2026
7 hours ago
daca and tps protest sign
LawDonald Trump
Supreme Court weighs Trump administration push to end protections for migrants from Haiti and Syria
By The Associated Press and Lindsay WhitehurstApril 29, 2026
9 hours ago
pete hegseth
PoliticsIran
‘A strategic blunder’: Democrats confront Hegseth as the Iran war’s price tag hits $25 billion
By The Associated Press, Ben Finley, Stephen Groves, David Klepper and Konstantin ToropinApril 29, 2026
10 hours ago

Most Popular

Apple cofounder Ronald Wayne—whose stake would be worth up to $400 billion had he not sold it in 1976—says that at 91, he has no regrets
Success
Apple cofounder Ronald Wayne—whose stake would be worth up to $400 billion had he not sold it in 1976—says that at 91, he has no regrets
By Preston ForeApril 27, 2026
3 days ago
‘Take the money and run’: Johns Hopkins economist Steve Hanke on why the UAE quit OPEC
Energy
‘Take the money and run’: Johns Hopkins economist Steve Hanke on why the UAE quit OPEC
By Shawn TullyApril 29, 2026
24 hours ago
‘The cost of compute is far beyond the costs of the employees’: Nvidia executive says right now AI is more expensive than paying human workers
AI
‘The cost of compute is far beyond the costs of the employees’: Nvidia executive says right now AI is more expensive than paying human workers
By Sasha RogelbergApril 28, 2026
2 days ago
Jamie Dimon gets candid about national debt: ‘There will be a bond crisis, and then we’ll have to deal with it’
Economy
Jamie Dimon gets candid about national debt: ‘There will be a bond crisis, and then we’ll have to deal with it’
By Eleanor PringleApril 29, 2026
20 hours ago
‘They left me no choice’: Powell isn’t going anywhere—blocking Trump from another Fed appointee
Banking
‘They left me no choice’: Powell isn’t going anywhere—blocking Trump from another Fed appointee
By Eva RoytburgApril 29, 2026
11 hours ago
More than two-thirds of U.S. schools say they’re unable to afford the cost of student free lunch—and MAHA’s dietary guidelines may make it worse
Economy
More than two-thirds of U.S. schools say they’re unable to afford the cost of student free lunch—and MAHA’s dietary guidelines may make it worse
By Sasha RogelbergApril 29, 2026
21 hours ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.