• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
Health

The U.S. confirms its first case of the Omicron variant in California

By
Michael Balsamo
Michael Balsamo
,
Zeke Miller
Zeke Miller
and
The Associated Press
The Associated Press
Down Arrow Button Icon
By
Michael Balsamo
Michael Balsamo
,
Zeke Miller
Zeke Miller
and
The Associated Press
The Associated Press
Down Arrow Button Icon
December 1, 2021, 2:55 PM ET

A person in California who had been vaccinated against COVID-19 became the first in the U.S. to have an identified case of the Omicron variant, the White House announced Wednesday as scientists continue to study the risks posed by the new virus strain.

Dr. Anthony Fauci told reporters the person was a traveler who returned from South Africa on Nov. 22 and tested positive on Nov. 29. Fauci said the person was vaccinated but had not received a booster shot and was experiencing “mild symptoms.”

The Biden administration moved late last month to restrict travel from Southern Africa where the variant was first identified and had been widespread. Clusters of cases have also been identified in about two dozen other nations.

“We knew that it was just a matter of time before the first case of Omicron would be detected in the United States,” Fauci said.

He said the person was improving and added, “I think what’s happening now is another example of why it’s important for people to get vaccinated. But also boosting. Boosting is very important.”

Officials said they had contacted everyone who had close contact with the person and they had all tested negative.

Genomic sequencing was conducted at the University of California, San Francisco and the sequence was confirmed by the Centers for Disease Control and Prevention.

The Centers for Disease Control and Prevention is taking steps to tighten U.S. testing rules for travelers from overseas, including requiring a test for all travelers within a day of boarding a flight to the U.S. regardless of vaccination status. It was also considering mandating post-arrival testing.

Officials said those measures would only “buy time” for the country to learn more about the new variant and to take appropriate precautions, but that given its transmissibility its arrival in the U.S. was inevitable.

Much remains unknown about the new variant, including whether it is more contagious than previous strains, whether it makes people more seriously ill, and whether it can thwart the vaccine. Fauci, the top U.S. infectious disease expert, said more would be known about the Omicron strain in two to four weeks as scientists grow and test lab samples of the virus.

California’s Department of Public Health credited the state’s “large-scale testing and early detection systems” for identifying the case.

“We recognize that everyone is exhausted, and the news of a new variant can be overwhelming. It is important that we collectively focus on the things we know prevent the spread of COVID-19, and its variants,” state public health officials said in a statement.

The announcement of the first U.S. case comes before President Joe Biden plans to outline his strategy on Thursday to combat the virus over the winter. Biden has tried to quell alarm over the Omicron variant, saying it was a cause for concern but “not a cause for panic.”

Biden and public health officials have grown more urgent in their pleas for more Americans to get vaccinated—and for those who have been vaccinated to get booster shots to maximize their protection against the virus.

Subscribe to Fortune Daily to get essential business stories straight to your inbox each morning.

About the Authors
By Michael Balsamo
See full bioRight Arrow Button Icon
By Zeke Miller
See full bioRight Arrow Button Icon
By The Associated Press
See full bioRight Arrow Button Icon

Latest in Health

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • Future 50
  • World’s Most Admired Companies
  • See All Rankings
Sections
  • Finance
  • Leadership
  • Success
  • Tech
  • Asia
  • Europe
  • Environment
  • Fortune Crypto
  • Health
  • Retail
  • Lifestyle
  • Politics
  • Newsletters
  • Magazine
  • Features
  • Commentary
  • Mpw
  • CEO Initiative
  • Conferences
  • Personal Finance
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
About Us
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Most Popular

placeholder alt text
North America
'I meant what I said in Davos': Carney says he really is planning a Canada split with the U.S. along with 12 new trade deals
By Rob Gillies and The Associated PressJanuary 28, 2026
2 days ago
placeholder alt text
Politics
The American taxpayer spent nearly half a billion dollars deploying federal troops to U.S. cities in 2025, CBO finds
By Nick LichtenbergJanuary 28, 2026
2 days ago
placeholder alt text
C-Suite
Jeff Bezos capped his Amazon salary at $80,000: ‘How could I possibly need more incentive?’
By Sydney LakeJanuary 28, 2026
2 days ago
placeholder alt text
C-Suite
Fortune 500 CEOs are no longer giving employees an A for effort. Now they want proof of impact
By Claire ZillmanJanuary 28, 2026
2 days ago
placeholder alt text
Investing
Jerome Powell got a direct question about the U.S. ‘losing credibility’ and the soaring price of gold and silver. He punted
By Eva RoytburgJanuary 29, 2026
1 day ago
placeholder alt text
Personal Finance
Current price of silver as of Thursday, January 29, 2026
By Joseph HostetlerJanuary 29, 2026
1 day ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.


Latest in Health

A person laying on a bed in a store.
Healthmattresses
How to Choose a Mattress: The Ultimate Guide
By Jessica RendallJanuary 30, 2026
36 minutes ago
HealthScience
As billionaires chase immortality, this startup cofounded by a Harvard genetics professor gets FDA approval for the first partial de-aging human trial
By Marco Quiroz-GutierrezJanuary 30, 2026
5 hours ago
C-SuiteFortune 500: Titans and Disruptors of Industry
Pfizer CEO says he used ‘emotional blackmail’ to get employees to achieve impossible goals during COVID-19
By Eva RoytburgJanuary 29, 2026
14 hours ago
man
HealthHealth
Life is actually getting better—and longer—for Americans, despite everything you read in the news
By Mike Stobbe and The Associated PressJanuary 29, 2026
18 hours ago
A pile of different-sized mattresses.
Healthmattresses
A Guide to All Mattress Dimensions: How to Choose the Right Size Bed
By Jessica RendallJanuary 29, 2026
19 hours ago
brooks
CommentaryInsurance
John Hancock CEO: We all have a role in driving better health outcomes for Americans
By Brooks TingleJanuary 29, 2026
24 hours ago