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NewslettersBrainstorm Health

CDC Homes In on the Chemical Villain Causing Mysterious Vaping Illnesses

By
Sy Mukherjee
Sy Mukherjee
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By
Sy Mukherjee
Sy Mukherjee
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November 8, 2019, 5:27 PM ET

This is the web version of Brainstorm Health Daily, Fortune’s daily newsletter on the top health care news. To get it delivered daily to your in-box, sign up here.

Hello and happy Friday, readers!

There’s been a rush to figure out what, exactly, is the chemical villain fueling a growing rash of vaping-related lung injuries and illnesses. The Centers for Disease Control (CDC) on Thursday announced that the total case count had climbed to 2,051, as well as 39 confirmed deaths.

We may finally be getting some answers. Potential culprits have included various compounds including vegetable glycerin, propylene glycol, and vitamin E acetate. But the latter was linked to all cases examined by the CDC, the agency announced in an update on Friday.

The CDC tested lung fluid samples from 29 patients across ten states; all of these sample included vitamin E acetate. The vast majority of the collected samples (82%) included the marijuana psychoactive compound THC while 62% contained nicotine (marijuana vaping pods, depending on the source they come from, may contain nicotine).

“This is the first time that we have detected a potential chemical of concern in biologic samples from patients with these lung injuries. These findings provide direct evidence of vitamin E acetate at the primary site of injury within the lungs,” wrote CDC researchers.

The agency also reiterated its warning to avoid THC-containing vaping products, especially if they come from the black market. And, to be clear, this is still a relatively small sample size, so there could well be other chemicals at play in the illness. But this could prove an initial breakthrough in this particular public health mystery.

Read on for the day’s news, and have a wonderful weekend.

Sy Mukherjee
sayak.mukherjee@fortune.com
@the_sy_guy

INDICATIONS

Takeda touts data for its dengue vaccine. Takeda scientists are hailing the results of a large scale study of an experimental dengue vaccine. The infectious disease afflicted can afflict 50 million to 100 million people per year and is listed as one of the top global health threats by the World Health Organization (WHO), and while it's not always fatal, it definitely can be. There is one (and just one) dengue vaccine currently on the market—Sanofi's pioneering Dengvaxia (which has had its own problems). But Takeda is claiming 80% effectiveness for its TAK-003, which uses a different action mechanism from Dengvaxia. More data, said researchers, will be needed to assess long-term safety and staying power. (NPR)

THE BIG PICTURE

For some firms, supporting abortion rights is a business decision, too. In June, nearly 200 top executives signed a full-page ad in the New York Times called "Don't Ban Equality" decrying the growing number of state and federal restrictions on abortion and reproductive health rights. But while that may be a moral and political choice made by some firms, it's also a business one, writes Jess McHugh for Fortune. "For corporations—especially in the land of Silicon Valley and tech start-ups—supporting women’s reproductive freedoms is good business. Many of their users skew female; they are increasingly attracting (or trying to attract) women employees, and for apps that rely on gig workers, abortion bans can even mean lost hours as contractors are forced to seek care out of state," says Jess. (Fortune)

REQUIRED READING

All Eyes Are on California as Uber and Lyft Fight Labor Leaders to Determine the Future of the Gig Economy, by Nicole Goodkind

SoftBank Created the Earnings Deck to End All Earnings Decks, by Polina Marinova

How Smart Cities and Homes Will Take China Into the Future, by Fortune Editors

The Chinese Entrepreneur Who Wants to Freeze Human Brains, by Adam Lashinsky

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