• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
Finance

Isis Pharmaceuticals Changes Its Name After Terrorists Attack Stock Price

By
Jen Wieczner
Jen Wieczner
Down Arrow Button Icon
By
Jen Wieczner
Jen Wieczner
Down Arrow Button Icon
December 18, 2015, 5:01 PM ET
Inside of a Gilead Sciences Lab
An automated machine works on purification of potential hepatitis C virus drug candidate at the Gilead Sciences Inc. lab in Foster City, California, U.S., on Wednesday, Feb. 8, 2012. Gilead acquired Pharmasset Inc. last month for its experimental hepatitis C treatments as it aims to compete with other drugmakers like Bristol-Myers Squibb Co. and Merck & Co. to develop a new class of oral cures for hepatitis C to replace older drugs that require injections. Photographer: David Paul Morris/Bloomberg via Getty ImagesPhotograph by David Paul Morris — Bloomberg via Getty Images

Isis Pharmaceuticals announced Friday that it is finally changing its name to something that people won’t confuse with the terrorist group that took credit for the recent Paris attacks and other deadly episodes of violence.

In explaining its decision to change its name to Ionis Pharmaceuticals, the biotech company did not mention terror explicitly. But for the company formerly known as Isis Pharmaceuticals (ISIS) for the past 26 years—whose soon-to-be-changed ticker symbol “ISIS” is identical to the widely used acronym for the Islamic State—the rise of the terrorist network had clearly become a growing problem.

In June 2014, a Wall Street Journal article speculated that an association with negative press about ISIS terrorists might be to blame for a 7% drop in the pharma firm’s stock. Last month after the Paris attacks, CNNMoney raised the possibility that terrorists had again struck Isis Pharmaceuticals’ shares, which fell 4% despite no relevant news. Over the past year, the company’s stock has lost 2.3%, underperforming the Nasdaq Biotechnology Index, which has returned more than 6%, as well as the S&P Pharmaceuticals Select Industry Index, which is just slightly down.

A spokesman for the company dismissed the connection, saying that when it surveyed its institutional investors and stock analysts about whether calling itself Isis was a problem, none had any issue with the name. “We haven’t seen any evidence that our name had any impact on our stock price,” Wade Walke, vice president of communications and investor relations for the Carlsbad, Cali.-based drugmaker, told Fortune. He acknowledged, however, that the company received “lots of calls and emails” from individual retail investors urging it to change its name. “It came down to the point where we were starting to get concerned about the distraction of our name being associated with the terrorist group,” he said.

Even if investors could consciously distinguish between the pharmaceutical company and the terrorists, it’s still possible the confusion could have moved the market. As Fortune detailed in a recent magazine feature, “How Investors Are Using Social Media to Make Money,” in its annual Investor’s Guide, traders are increasingly using algorithms to scan social media and other websites for key terms, triggering computers to buy or sell stocks automatically. But the algorithms aren’t always sophisticated enough to tell the difference between Isis the stock and ISIS the terrorist organization.

Last year, Ionis’s CEO (which was then called Isis) Stanley Crooke told CNBC that sharing the name with terrorists “drives me crazy.” But he also expressed his reluctance to be influenced by the group, adopting a we-don’t-negotiate-with-terrorists sort of attitude. “I don’t feel that I want to capitulate to these terrorists by changing my name,” he said in the interview. “They can change their name.”

Since then, though, the company became concerned that any association with ISIS might pose additional risks to the safety or wellbeing of its employees, particularly if they were traveling, Walke said. He personally experienced the potential problems when he told a local police officer earlier this year that he worked for Isis, whose offices were nearby. The officer responded, “‘You mean the group that cuts people’s heads off?'” Walke recounted. “We want people when they hear or say our name to think about the incredible drugs we’re developing and not a terrorist group.”

While the biotech company’s name was originally chosen more than a quarter-century ago after the Egyptian goddess of health, the company’s new name Ionis doesn’t have any particular significance. The stock will begin trading under ticker symbol “IONS” next week on Dec. 22.

About the Author
By Jen Wieczner
See full bioRight Arrow Button Icon

Latest in Finance

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • Future 50
  • World’s Most Admired Companies
  • See All Rankings
Sections
  • Finance
  • Leadership
  • Success
  • Tech
  • Asia
  • Europe
  • Environment
  • Fortune Crypto
  • Health
  • Retail
  • Lifestyle
  • Politics
  • Newsletters
  • Magazine
  • Features
  • Commentary
  • Mpw
  • CEO Initiative
  • Conferences
  • Personal Finance
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
About Us
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Most Popular

placeholder alt text
Economy
'I just don't have a good feeling about this': Top economist Claudia Sahm says the economy quietly shifted and everyone's now looking at the wrong alarm
By Eleanor PringleJanuary 31, 2026
24 hours ago
placeholder alt text
Success
Ryan Serhant starts work at 4:30 a.m.—he says most people don’t achieve their dreams because ‘what they really want is just to be lazy’
By Preston ForeJanuary 31, 2026
19 hours ago
placeholder alt text
Future of Work
Ford CEO has 5,000 open mechanic jobs with up to 6-figure salaries from the shortage of manually skilled workers: 'We are in trouble in our country'
By Marco Quiroz-GutierrezJanuary 31, 2026
16 hours ago
placeholder alt text
Success
Alexis Ohanian walked out of the LSAT 20 minutes in, went to a Waffle House, and decided he was 'gonna invent a career.' He founded Reddit
By Preston ForeJanuary 31, 2026
16 hours ago
placeholder alt text
Economy
Right before Trump named Warsh to lead the Fed, Powell seemed to respond to some of his biggest complaints about the central bank
By Jason MaJanuary 30, 2026
2 days ago
placeholder alt text
AI
Top engineers at Anthropic, OpenAI say AI now writes 100% of their code—with big implications for the future of software development jobs
By Beatrice NolanJanuary 29, 2026
3 days ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.


Latest in Finance

Startups & VentureOpenAI
Nvidia CEO signals investment in OpenAI round may be largest yet
By Debby Wu and BloombergJanuary 31, 2026
8 hours ago
Economygeopolitics
BRICS could become a new pillar of global governance—if its rapid growth doesn’t erode its newfound clout
By Brian WongJanuary 31, 2026
9 hours ago
EconomyFederal Reserve
Fed chair nominee Kevin Warsh could crush Trump’s rate-cut hopes and risk suffering the same level of abuse that Powell got, analysts say
By Jason MaJanuary 31, 2026
9 hours ago
EconomyDebt
Trump thinks a weaker dollar is great, but the U.S. needs a stable currency as national debt heads toward $40 trillion, former Fed president says
By Jason MaJanuary 31, 2026
11 hours ago
Startups & VentureVenture Capital
Silicon Valley legend Kleiner Perkins was written off. Then an unlikely VC showed up
By Allie GarfinkleJanuary 31, 2026
13 hours ago
North AmericaDrugs
Mexico’s ban on vapes could give drug cartels more revenue — ‘those selling cocaine, fentanyl, marijuana are selling you vapes’
By María Verza and The Associated PressJanuary 31, 2026
13 hours ago