Amgen (Nasdaq: AMGN) has agreed to acquire Micromet Inc. (Nasdaq:MITI) for approximately $1.16 billion in cash, or $11 per share (33% premium to yesterday’s closing price). www.amgen.com

Celgene Corp. (Nasdaq: CELG) has agreed to acquire Avila Therapeutics Inc., a Waltham, Mass.–based developer of targeted covalent drugs that treat diseases through protein silencing. The deal is valued at $350 million in cash, plus up to another $195 million in earn-outs. Avila shareholders include Abingworth, Advent Venture Partners, Atlas Venture, Novartis Venture Funds and Polaris Venture Partners. www.celgene.com

CIC Partners has sold its stake in Legends Hospitality Management, a provider of hospitality, merchandising and premium ticketing services that was founded by CIC, the New York Yankees, the Dallas Cowboys and Goldman Sachs. The buyer is Checketts Partners Investment Fund, and Dave Checketts will take over as Legends chairman and CEO. The prior CEO, CIC Partners exec Michael Rawlings, was recently elected the mayor of Dallas. No financial terms were disclosed. www.cicpartners.com

Illumina (Nasdaq: ILMN) has adopted a shareholder rights plan, following a $5.7 billion hostile takeover bid from Switzerland’s Roche Holdings. www.illumina.com

Sara Lee Corp. (NYSE: SLE) has agreed to acquire the Senseo coffee systems assets of Philips Electronics NV for €170 million. Sara Lee previously co-owned Senseo with Philips. www.saralee.com

Thoratec Corp.
(Nasdaq: THOR) said its second-largest shareholder has withdrawn calls for the company to hire an investment bank to help explore strategic alternatives. The cardiac-device maker has a current market cap of approximately $1.85 billion. www.thoratec.com

US Airways Group (NYSE: LCC) confirmed to Bloomberg that it is considering an offer for bankrupt American Airlines. www.usair.com

United Technologies Corp. (NYSE: UTX) said that it is planning to sell select “non-core” assets prior to acquiring Goodrich Corp. (NYSE: GR) for $16.5 billion. No specific assets were identified. It also plans to raise new equity ($4 billion) and debt financing.

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