• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
Commentary

AI agents are becoming power users of enterprise software and deciding which tools to buy next—and Microsoft knows it

By
Tomasz Tunguz
Tomasz Tunguz
Down Arrow Button Icon
By
Tomasz Tunguz
Tomasz Tunguz
Down Arrow Button Icon
June 10, 2025, 11:29 AM ET

Tomasz Tunguz is the founder and general manager of Theory Ventures. He served as managing partner at Redpoint Ventures for 14 years.

Microsoft CEO Satya Nadella.
Microsoft CEO Satya Nadella.JASON REDMOND/AFP via Getty Images

AI is transforming how enterprise software gets bought—not by replacing users, but by becoming one. 

The debate around AI and the workplace often centers on labor displacement: Will it replace workers? Where will it fall short? And indeed, some “AI-first” experiments have produced mixed results—Klarna reversed course on customer service automation, while Duolingo faced public backlash for an AI-focused growth strategy. 

These outcomes complicate our understanding of Microsoft’s recent efficiency-driven layoffs. Unlike a premature overcommitment to automation (à la Klarna), Microsoft is restructuring to operate as “customer zero” for its own enterprise AI tools, fundamentally changing how the computing giant writes code, ships products, and supports clients. It’s a strategic shot in the arm—a painful one—that reveals what’s coming next: AI agents built not just to automate outcomes, but to make decisions about the tools, processes, and infrastructure used along the way. 

AI agent as orchestrator

In the past, enterprise software was chosen through a familiar dance: evaluation, demos, stakeholder alignment, and procurement. But today, AI agents are building applications, provisioning infrastructure, and selecting tools—autonomously, and at scale. Ask an agent to spin up a customer feedback portal, and it might choose Next.js for the frontend, Neon for the cloud database, Vercel for hosting, and Clerk for authentication as a service. No human has to Google options, compare vendors, or meet with salespeople. The agent simply acts.

Internal telemetry from Neon shows that AI agents now create databases at 4 times the rate of human developers. And that pattern is extending beyond engineering. Agents will soon assemble sales pipelines, orchestrate onboarding flows, manage IT operations—and, along the way, select the tools that work. 

Microsoft’s sales team re-org further hints at how this procurement will occur in the future. Corporate customers now have a single point of contact at Microsoft, rather than several salespeople for different products. In part, this may be because agentic AI tools will select vendors on their own—and copilots don’t need five sales reps. The agent won’t pause to ask, “Do you have a preferred vendor?” It will reason about the task at hand and continue on its code path, hurtling toward an answer.

Human-in-the-loop AI

This evolution from executor to decision-maker is powered by the human-in-the-loop (HITL) approach to AI model training.

For years, enterprise AI has been limited by expensive labeling processes, fragile automation, and underutilized human expertise, leading to failure in nuanced, high-stakes environments like finance, customer service, and health care.

HITL systems change that by embedding AI directly into the workforce. During real-time work, agents observe GUI-level interactions—clicks, edits, approvals—capturing rich signals from natural behavior. These human corrections serve as high-quality validation points, boosting operational accuracy to ~99% without interrupting the workflow. The result is a continuous learning loop where agents don’t just follow instructions, they learn how the work gets done. This also creates dynamic, living datasets tailored to real business processes within the organization.

This shift offers entirely new market opportunities. 

On the development front, traditional supervised learning models are giving way to embedded learning systems that harvest real-world interaction signals, enabling cheaper, faster, more adaptive AI. This further offers a massive new training set for agentic AI systems without incurring the cost of hiring human knowledge workers to shepherd the AI. With lower development costs, high fidelity, and better dynamism, the next generation of copilots will blend automation with real-time human judgment, dominating verticals like customer service, security, sales, and internal operations. 

Accordingly, these tools will require infrastructure for real-time monitoring, GUI-level interaction capture, dynamic labeling, and automated retraining—creating further platform opportunities.

Microsoft’s sense of urgency

While the internet abounds with zippy coverage of savvy employees “AI hacking” their workflows, the reality is most workers lack that kind of product-development acumen. (And same for their bosses.) Save for a small subset of the business world possessing rare tech fluency, most corporate outfits will see greater value in buying AI tools—those built, customized, and serviced by world-class talent to solve specific workflows.

Microsoft’s sense of urgency comes from its understanding that the question of “build or buy” is changing quickly. This “eureka” moment, technologically speaking, is what’s catalyzing an operator pivot at enterprise AI outfits. HITL represents a move away from read/write data integrations toward a richer, more dynamic GUI-interaction-based intelligence layer—one that mirrors how work actually gets done in the enterprise. 

We’re seeing the beginning of a race toward enterprise AI dominance among the goliaths of the tech world. Signals like OpenAI’s investments into application-layer experiences (shopping agents, its acquisition of agentic developer Windsurf) highlight a clear trend: Mastering human-application-interaction capture is becoming the foundation for scalable agentic automation. As companies like Microsoft, OpenAI, and others absorb critical data environments and restructure themselves to serve as “customer zero,” they’re treating AI as the new chief procurement officer of their own ecosystems. These companies see the value of selling shovels in a gold rush—and know AI is finally sharp enough to start digging.

The opinions expressed in Fortune.com commentary pieces are solely the views of their authors and do not necessarily reflect the opinions and beliefs of Fortune.

Read more:

  • ‘Sovereign AI’ is political branding. The reality is closer to digital colonialism
  • Trump has inadvertently shown Europe it needs to build a full-stack AI industry—and avoid a risky reliance
  • The AI cost collapse is changing what’s possible—with massive implications for tech startups
  • When AI builds AI: The next great inventors might not be human
Join us at the Fortune Workplace Innovation Summit May 19–20, 2026, in Atlanta. The next era of workplace innovation is here—and the old playbook is being rewritten. At this exclusive, high-energy event, the world’s most innovative leaders will convene to explore how AI, humanity, and strategy converge to redefine, again, the future of work. Register now.
About the Author
By Tomasz Tunguz
See full bioRight Arrow Button Icon

Latest in Commentary

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Fortune Secondary Logo
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • Future 50
  • World’s Most Admired Companies
  • See All Rankings
Sections
  • Finance
  • Fortune Crypto
  • Features
  • Leadership
  • Health
  • Commentary
  • Success
  • Retail
  • Mpw
  • Tech
  • Lifestyle
  • CEO Initiative
  • Asia
  • Politics
  • Conferences
  • Europe
  • Newsletters
  • Personal Finance
  • Environment
  • Magazine
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
  • Group Subscriptions
About Us
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Latest in Commentary

assis
CommentaryIBM
The digital sovereignty dilemma is a false choice — here’s how enterprises can have both
By Ana Paula AssisApril 9, 2026
1 day ago
housing
CommentaryHousing
The housing market has been frozen for 3 years. Here’s why this spring could finally change that
By Jessica LautzApril 8, 2026
2 days ago
curtin
CommentaryInfrastructure
TE Connectivity CEO: the real promise of AI is long-term transformation, not short-term efficiency gains
By Terrence CurtinApril 7, 2026
3 days ago
philip
CommentaryEducation
I just became CEO of one of education’s Big 3. Here’s why AI will never replace a great teacher
By Philip MoyerApril 7, 2026
3 days ago
omar
Commentarydisruption
Pearson CEO: the AI job apocalypse is a Silicon Valley story. The data tells a different one
By Omar AbboshApril 6, 2026
4 days ago
no kings
CommentaryLeadership
America’s CEOs have become reluctant guardians of democracy
By Jeffrey Sonnenfeld and Stephen HenriquesApril 6, 2026
4 days ago

Most Popular

The U.S. government is spending $88 billion a month in interest on national debt—equal to spending on defense and education combined
Economy
The U.S. government is spending $88 billion a month in interest on national debt—equal to spending on defense and education combined
By Fortune EditorsApril 9, 2026
24 hours ago
A Meta employee created a dashboard so coworkers can compete to be the company's No. 1 AI token user—and Zuckerberg doesn't even rank in the top 250
AI
A Meta employee created a dashboard so coworkers can compete to be the company's No. 1 AI token user—and Zuckerberg doesn't even rank in the top 250
By Fortune EditorsApril 9, 2026
1 day ago
Gen Z doesn't want your full-time job. They want several part-time roles, and it's reshaping the entire workforce
Success
Gen Z doesn't want your full-time job. They want several part-time roles, and it's reshaping the entire workforce
By Fortune EditorsApril 9, 2026
1 day ago
White-collar workers are quietly rebelling against AI as 80% outright refuse adoption mandates
AI
White-collar workers are quietly rebelling against AI as 80% outright refuse adoption mandates
By Fortune EditorsApril 9, 2026
1 day ago
Gen Z workers are so fearful AI will take their job they’re intentionally sabotaging their company’s AI rollout
AI
Gen Z workers are so fearful AI will take their job they’re intentionally sabotaging their company’s AI rollout
By Fortune EditorsApril 8, 2026
2 days ago
Current price of oil as of April 9, 2026
Personal Finance
Current price of oil as of April 9, 2026
By Fortune EditorsApril 9, 2026
22 hours ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.