• Home
  • News
  • Fortune 500
  • Tech
  • Finance
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
TechAI

Microsoft, ex-Google CEO back startup that aims to make AI systems work as humans intended

By
Rachel Metz
Rachel Metz
and
Bloomberg
Bloomberg
Down Arrow Button Icon
By
Rachel Metz
Rachel Metz
and
Bloomberg
Bloomberg
Down Arrow Button Icon
February 29, 2024, 6:03 PM ET
Former Google CEO Eric Schmidt has backed Synth Labs, seeing the need to align AI actions with human intentions.
Former Google CEO Eric Schmidt has backed Synth Labs, seeing the need to align AI actions with human intentions. Lukas Schulze/Sportsfile for Collision via Getty Images

Artificial intelligence software doesn’t always do what the people building it want it to do — a potentially dangerous issue that has consumed some of the largest companies working on the technology.

Big companies like OpenAI and Alphabet Inc.’s Google are increasingly directing workers, money and computing power toward the problem. And Anthropic, an OpenAI competitor, has put it at the heart of its development of Claude, a product it bills as a safer kind of AI chatbot.

Starting this month, a new company called Synth Labs is also taking aim at the issue. Founded by a handful of prominent AI industry names, the company is emerging from stealth this week, and has raised seed funding from Microsoft Corp.’s venture capital fund, M12, and Eric Schmidt’s First Spark Ventures. Synth Labs is primarily focused on building software, some of it open source, to help a range of companies ensure that their AI systems act according to their intentions. It’s positioning itself as a company that’s working transparently and collaboratively.

Alignment, as the issue is sometimes called, represents a technical challenge for AI applications such as chatbots that are built atop large language models, which are typically trained on huge swaths of internet data. The effort is complicated by the fact that people’s ethics and values — as well as their ideas of what AI should and should not be permitted to do — vary. Synth Labs’ products will aim to help steer and customize large language models, particularly models that are themselves open source.

The company got its start as a project within nonprofit AI research lab EleutherAI, worked on by two of the three founders — Louis Castricato and Nathan Lile — plus Synth Labs advisor and EleutherAI executive director Stella Biderman. Francis deSouza, former chief executive officer of biotechnology company Illumina Inc., is also a founder. Synth Labs declined to say how much money it had raised so far.

Over the last few months the startup has built tools that can readily evaluate large language models on complex topics, Castricato said. The goal, he said, is to democratize access to easy-to-use tools that can automatically evaluate and align AI models.

A recent research paper that Castricato, Lile and Biderman co-authored gives a sense for the company’s approach: The authors used responses to prompts, which were generated by OpenAI’s GPT-4 and Stability AI’s Stable Beluga 2 AI models, to create a dataset. That dataset was then used as part of an automated process to direct a chatbot to avoid talking about one topic and instead talk about another.

“The way that we’re thinking about designing some of these early tools really is all about giving you the opportunity to decide what alignment means for your business or your personal preferences,” Lile said.

Fortune Brainstorm AI returns to San Francisco Dec. 8–9 to convene the smartest people we know—technologists, entrepreneurs, Fortune Global 500 executives, investors, policymakers, and the brilliant minds in between—to explore and interrogate the most pressing questions about AI at another pivotal moment. Register here.
About the Authors
By Rachel Metz
See full bioRight Arrow Button Icon
By Bloomberg
See full bioRight Arrow Button Icon

Latest in Tech

LawInternet
A Supreme Court decision could put your internet access at risk. Here’s who could be affected
By Dave Lozo and Morning BrewDecember 2, 2025
7 hours ago
AITikTok
China’s ByteDance could be forced to sell TikTok U.S., but its quiet lead in AI will help it survive—and maybe even thrive
By Nicholas GordonDecember 2, 2025
8 hours ago
United Nations
AIUnited Nations
UN warns about AI becoming another ‘Great Divergence’ between rich and poor countries like the Industrial Revolution
By Elaine Kurtenbach and The Associated PressDecember 2, 2025
10 hours ago
Anthropic cofounder and CEO Dario Amodei
AIEye on AI
How Anthropic’s safety first approach won over big business—and how its own engineers are using its Claude AI
By Jeremy KahnDecember 2, 2025
10 hours ago
Nvidia founder and CEO Jensen Huang reacts during a press conference at the Asia-Pacific Economic Cooperation (APEC) CEO Summit in Gyeongju on October 31, 2025.
AINvidia
Nvidia CFO admits the $100 billion OpenAI megadeal ‘still’ isn’t signed—two months after it helped fuel an AI rally
By Eva RoytburgDecember 2, 2025
12 hours ago
Big TechInstagram
Instagram CEO calls staff back to the office 5 days a week to build a ‘winning culture’—while canceling every recurring meeting
By Marco Quiroz-GutierrezDecember 2, 2025
12 hours ago

Most Popular

placeholder alt text
Economy
Ford workers told their CEO 'none of the young people want to work here.' So Jim Farley took a page out of the founder's playbook
By Sasha RogelbergNovember 28, 2025
4 days ago
placeholder alt text
Success
Warren Buffett used to give his family $10,000 each at Christmas—but when he saw how fast they were spending it, he started buying them shares instead
By Eleanor PringleDecember 2, 2025
18 hours ago
placeholder alt text
Economy
Elon Musk says he warned Trump against tariffs, which U.S. manufacturers blame for a turn to more offshoring and diminishing American factory jobs
By Sasha RogelbergDecember 2, 2025
12 hours ago
placeholder alt text
C-Suite
MacKenzie Scott's $19 billion donations have turned philanthropy on its head—why her style of giving actually works
By Sydney LakeDecember 2, 2025
19 hours ago
placeholder alt text
Success
Forget the four-day workweek, Elon Musk predicts you won't have to work at all in ‘less than 20 years'
By Jessica CoacciDecember 1, 2025
1 day ago
placeholder alt text
AI
More than 1,000 Amazon employees sign open letter warning the company's AI 'will do staggering damage to democracy, our jobs, and the earth’
By Nino PaoliDecember 2, 2025
20 hours ago
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • Future 50
  • World’s Most Admired Companies
  • See All Rankings
Sections
  • Finance
  • Leadership
  • Success
  • Tech
  • Asia
  • Europe
  • Environment
  • Fortune Crypto
  • Health
  • Retail
  • Lifestyle
  • Politics
  • Newsletters
  • Magazine
  • Features
  • Commentary
  • Mpw
  • CEO Initiative
  • Conferences
  • Personal Finance
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
About Us
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map

© 2025 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.