• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
HealthInvesting

Why a biotech firm’s market value jumped from $3 million to $130 million in a day and is still way up from its ‘almost unfathomably low valuation’

By
Angel Adegbesan
Angel Adegbesan
and
Bloomberg
Bloomberg
Down Arrow Button Icon
By
Angel Adegbesan
Angel Adegbesan
and
Bloomberg
Bloomberg
Down Arrow Button Icon
October 13, 2023, 4:26 PM ET
Severin Schwan, chairman of Switzerland's pharmaceutical giant Roche Group.
Severin Schwan, chairman of Switzerland's pharmaceutical giant Roche Group.ERIC PIERMONT/AFP via Getty Images

An under-the-radar biotech firm called Tempest Therapeutics Inc. is set to notch its best week on record after results from a liver cancer trial sent the stock surging 3,973% — and tumbling the next day.

Wall Street cheered as the stock shot up to $9.77 on Wednesday when the drug developer said its experimental cancer therapy in a cocktail with two Roche Holding AG drugs worked better than the pair of drugs by themselves. The surge after the Roche-run study helped push Tempest’s market value to $130 million from a mere $3 million as of the previous day’s close.

Shares of Tempest have come off that high in the two latest trading sessions as investor enthusiasm moderated and a broader market selloff in risky assets batters the high-risk biotechnology sector. The firm’s current market value of $54 million remains more than 16-fold of what it was, before the jump.

Tempest was “coming from an almost unfathomably low valuation going into this data readout,” as investors were skeptical following earlier study results, according to William Blair analyst Matt Phipps. “The company is still clearly undervalued for the blockbuster opportunity” of its cancer drug, he wrote in a note dated Wednesday.

Analysts tracked by Bloomberg that cover the company are universally bullish, with all four rating Tempest the equivalent of a buy. The average of three price targets suggests the stock could more than quadruple from its current $4 a share level.

HC Wainwright & Co. analyst Joseph Pantginis expects Tempest to ride the wave to a market capitalization of about $770 million. Yet, Pantginis said his valuation estimate is only based on a 25% projected chance of success for the trial, which he calls “conservative.” He boosted his price target to $47 this week, the highest among three analyst targets.

“Significant upside potential remains,” he wrote, citing the market for liver cancer drugs and the possibility of Tempest’s drug being part of the first-line of treatment for patients.

The Fortune 500 Innovation Forum will convene Fortune 500 executives, U.S. policy officials, top founders, and thought leaders to help define what’s next for the American economy, Nov. 16-17 in Detroit. Apply here.
About the Authors
By Angel Adegbesan
See full bioRight Arrow Button Icon
By Bloomberg
See full bioRight Arrow Button Icon

Latest in Health

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Fortune Secondary Logo
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • Future 50
  • World’s Most Admired Companies
  • See All Rankings
Sections
  • Finance
  • Fortune Crypto
  • Features
  • Leadership
  • Health
  • Commentary
  • Success
  • Retail
  • Mpw
  • Tech
  • Lifestyle
  • CEO Initiative
  • Asia
  • Politics
  • Conferences
  • Europe
  • Newsletters
  • Personal Finance
  • Environment
  • Magazine
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
  • Group Subscriptions
About Us
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Latest in Health

US President Donald Trump speaks to reporters before boarding Air Force One at Palm Beach International Airport in West Palm Beach, Florida, on March 23, 2026.
HealthIran
Trump has TACO’d again, this time in Iran, sparking a $1.7 trillion stock market rally in minutes, even as peace talks are in question
By Eva RoytburgMarch 23, 2026
7 hours ago
HealthHealth
Forest ‘bathing’ can reduce stress, improve mood, lower blood pressure and boost the immune system. Here’s how it’s done
By Allen Breed and The Associated PressMarch 22, 2026
1 day ago
HealthHealth
It’s not just vaccines. Parents are refusing other routine preventive care for newborns—even protection from severe bleeding and blindness
By Laura Ungar and The Associated PressMarch 21, 2026
2 days ago
Healthmeal delivery
The 6 Best Gluten-Free Meal Delivery Services of 2026: Nutritionist Approved
By Emily PharesMarch 20, 2026
3 days ago
Healthmeal delivery
Home Chef Meal Delivery Review (2026): Taste Tester Approved
By Christina SnyderMarch 20, 2026
3 days ago
Healthmeal delivery
The 4 Best Frozen Meal Delivery Services (2026): Personally Taste Tested
By Christina SnyderMarch 20, 2026
3 days ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.