• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia

Trendingnow

1

Analysts expected oil to surge above $200 but China has quietly kept prices half of that—and can’t for much longer

2

Marc Lore’s robots make 500 burrito bowls an hour. A human can make 45

3

Pentagon accuses Alibaba, Baidu and BYD, three of China's biggest companies, of supporting the Chinese military

1

Analysts expected oil to surge above $200 but China has quietly kept prices half of that—and can’t for much longer

2

Marc Lore’s robots make 500 burrito bowls an hour. A human can make 45

3

Pentagon accuses Alibaba, Baidu and BYD, three of China's biggest companies, of supporting the Chinese military
CommentaryCOVID-19 vaccines

How game theory could solve the COVID vaccine rollout puzzle

By
Luke Muggy
Luke Muggy
Down Arrow Button Icon
By
Luke Muggy
Luke Muggy
Down Arrow Button Icon
March 10, 2021, 5:30 PM ET
People wait in vehicles at a COVID-19 vaccination site at Dodger Stadium in Los Angeles. Game theory could help public health authorities avoid overcrowding and shortages, writes Luke Muggy.
People wait in vehicles at a COVID-19 vaccination site at Dodger Stadium in Los Angeles. Game theory could help public health authorities avoid overcrowding and shortages, writes Luke Muggy. Bing Guan—Bloomberg/Getty Images

People may be familiar with stories of long lines at vaccination centers in Los Angeles and New York City, but there are also examples of expiring vaccines being hastily administered to whoever happened to be near a health clinic, or even in the middle of traffic during a snowstorm. Instead of a single national strategy, the logistical responsibility of administering millions of vaccines has been pushed to local levels, forcing individual health systems to find solutions. The health systems behind the rollout of COVID-19 vaccinations are attempting to create order from chaos, sometimes with mixed results. 

Rather than rely on improvisation and on-the-fly decision-making, state authorities should consider turning to mathematics for a tool that could prove to be the key to more efficient, faster vaccine distribution. That tool: the discipline known as game theory. 

Game theory is a field of mathematics that models competitive and cooperative human interactions, where a “game” is composed of players, their actions, and the resulting payoffs. Often applied to competitive economic and political contexts, game theory can be valuable for predicting behavior and incentivizing decisions that improve a broader system. In the context of health care, it models individuals’ decision-making criteria when accessing health services. 

In the COVID-19 vaccine rollout, the “players” would be individuals seeking care; the actions would be the individuals’ selection of a facility; and the payoffs would be measured in terms of how individuals perceive the risk of vaccination, distance traveled, and level of service available at a chosen facility. The level of service might be captured in terms of the congestion of facilities or a supply-demand ratio.

In past research, game theory predicted whether or not individuals would vaccinate, if herd immunity could be achieved, potential vaccine accessibility, and how individuals select vaccination centers. Among other things, these analyses can help calculate how many vaccines need to be sent to each vaccination center. This approach has been proven valuable in after-the-fact analyses of the H1N1 vaccination campaign in 2009 and the response to Haiti’s cholera epidemic in 2010. In those scenarios it enabled the identification of “equilibrium solutions,” which represent how individuals may select vaccination centers when given the freedom to choose. 

When equilibrium solutions involve overwhelmed vaccination centers, a city might offer free transportation from certain neighborhoods to more distant centers, incentivizing individuals to spread demand more evenly. Another opportunity might be to openly share data concerning the vaccine supply, wait times, and the likely demand at each center. This may enable people to make more informed choices. It also could benefit the overall system and lessen system stress, as nobody would be likely to knowingly select an overcrowded vaccine center.

The concept of equilibrium is also valuable when a centralized planner has the ability to assign individuals to facilities, because it allows the planner to implement equilibrium solutions, creating an assignment in which no individual can do better by switching facilities. Otherwise, the public may reject a health system’s proposed strategy, either by overwhelming some centers and underutilizing others, or by refusing vaccination altogether. In addition to finding equilibrium solutions, a centralized planner might wish to ensure these solutions minimize the scarcity of vaccines across centers, minimize the cumulative distance traveled and congestion at facilities, or maximize efficient and equitable access to vaccines.

As vaccine centers expand from health clinics and hospitals to stadiums and event centers, and administrators are encouraged not to stockpile vaccines, it is important to use the best management tools at our disposal—including game theory.

It’s time we stopped measuring “what could have been” scenarios and begin applying game theory to create what could be. 

Luke Muggy is a full operations researcher focusing on humanitarian logistics systems at the nonprofit, nonpartisan RAND Corporation.

About the Author
By Luke Muggy
See full bioRight Arrow Button Icon

Latest in Commentary

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Fortune Secondary Logo
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • World's Most Admired Companies
  • See All Rankings
  • Lists Calendar
Sections
  • Finance
  • Fortune Crypto
  • Features
  • Leadership
  • Health
  • Commentary
  • Success
  • Retail
  • Mpw
  • Tech
  • Lifestyle
  • CEO Initiative
  • Asia
  • Politics
  • Conferences
  • Europe
  • Newsletters
  • Personal Finance
  • Environment
  • Magazine
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
  • Group Subscriptions
About Us
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Latest in Commentary

Three ways that Asia’s enterprises are adopting AI—and where they are falling behind
CommentaryOracle
Three ways that Asia’s enterprises are adopting AI—and where they are falling behind
By Garrett IlgJune 11, 2026
5 hours ago
gordon
CommentaryVenture Capital
Gordon Ritter: I predicted AI’s learning loop a decade ago. The doomers are still measuring the wrong thing
By Gordon RitterJune 11, 2026
14 hours ago
bessent
CommentarySocial Security
Social Security and Medicare are heading toward insolvency. Congress has 6 years to act
By Steve H. Hanke and David M. WalkerJune 11, 2026
16 hours ago
Digital sovereignty isn’t the same thing as digital isolation. Asia’s governments should be careful
Commentarydata sovereignty
Digital sovereignty isn’t the same thing as digital isolation. Asia’s governments should be careful
By Leonard LimJune 10, 2026
1 day ago
tim
CommentaryAirline industry
Merlin CTO: autonomy can rebuild the foundation of aviation — and national security
By Tim BurnsJune 9, 2026
3 days ago
dewar
CommentaryLeadership
I founded McKinsey’s CEO practice: Here’s why operational excellence is a liability right now
By Carolyn DewarJune 9, 2026
3 days ago

Most Popular

Analysts expected oil to surge above $200 but China has quietly kept prices half of that—and can’t for much longer
Energy
Analysts expected oil to surge above $200 but China has quietly kept prices half of that—and can’t for much longer
By Sasha RogelbergJune 10, 2026
1 day ago
Marc Lore’s robots make 500 burrito bowls an hour. A human can make 45
Innovation
Marc Lore’s robots make 500 burrito bowls an hour. A human can make 45
By Amanda GerutJune 9, 2026
2 days ago
Pentagon accuses Alibaba, Baidu and BYD, three of China's biggest companies, of supporting the Chinese military
Asia
Pentagon accuses Alibaba, Baidu and BYD, three of China's biggest companies, of supporting the Chinese military
By Kate O'Keeffe and BloombergJune 8, 2026
3 days ago
Corporate America has been draining the world's water. Matt Damon's new campaign calls on Gap, Starbucks, and Amazon to help give it back
Environment
Corporate America has been draining the world's water. Matt Damon's new campaign calls on Gap, Starbucks, and Amazon to help give it back
By Catherina GioinoJune 9, 2026
3 days ago
Current price of oil as of June 11, 2026
Personal Finance
Current price of oil as of June 11, 2026
By Joseph HostetlerJune 11, 2026
13 hours ago
Costco CEO Ron Vachris rose from forklift driver to the C-suite without a college degree: ‘Don’t chase a title’ is the career advice that got him there
Success
Costco CEO Ron Vachris rose from forklift driver to the C-suite without a college degree: ‘Don’t chase a title’ is the career advice that got him there
By Preston ForeJune 8, 2026
3 days ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.