Big Pharma’s Return on Investment Plummets to a Dismal 10-Year Low

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Good afternoon, readers.

I know we’re all supposed to be cheery going into the holidays, but I have some bad news: Legacy biopharma companies are still in a rut.

Or at least that’s what the experts over at Deloitte have to say in a new report finding that, for the top 12 biopharma companies, the return on investment for R&D has fallen to a dismal 1.8%.

That’s a decade-long low, and somehow even lower than last year’s 1.9% ROI (for comparison, the number stood at 10.1% in 2010).

The reasons are plentiful. Among them: A tougher regulatory environment and an ever-shifting R&D picture which now favors smaller, leaner firms over the giants of old. And even within that narrative, things are complicated, according to Deloitte’s Neil Lesser.

“The current model is not a sustainable one for success,” Lesser told Fortune in an interview.

But there are some plus points, too.

“Companies continue to see a lot of success with individualized and personalized medications,” said Lesser, adding that the model “hasn’t reached the volumes that the blockbuster model of multi-billion dollar drugs was based on.”

This ROI plummet may help explain, as we’ve previously explored, major drug companies’ insistence on hiking prices and engaging in expensive bolt-on acquisitions.

Read on for the day’s news.

Sy Mukherjee
sayak.mukherjee@fortune.com
@the_sy_guy

DIGITAL HEALTH

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INDICATIONS

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