• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia

Trendingnow

1

'We didn’t see this coming': Wall Street eats its forecasts as stocks sell off globally on fear of AI bubble ahead of SpaceX IPO

2

Gen Zers are arriving at college unable to even read a sentence—professors warn it could lead to a generation of anxious and lonely graduates

3

Trump, who has repeatedly called climate change fake, is now threatening Brazil with tariffs over the deforestation of the Amazon

1

'We didn’t see this coming': Wall Street eats its forecasts as stocks sell off globally on fear of AI bubble ahead of SpaceX IPO

2

Gen Zers are arriving at college unable to even read a sentence—professors warn it could lead to a generation of anxious and lonely graduates

3

Trump, who has repeatedly called climate change fake, is now threatening Brazil with tariffs over the deforestation of the Amazon
FinanceTerm Sheet

Pfizer CEO on AstraZeneca management: They need convincing

By
Jennifer Reingold
Jennifer Reingold
Down Arrow Button Icon
By
Jennifer Reingold
Jennifer Reingold
Down Arrow Button Icon
April 28, 2014, 9:47 PM ET

On Monday, Pfizer (PFE) publicly announced its interest in acquiring British drug giant AstraZeneca — an overture that the U.K. firm has so far met with silence, at least publicly. It’s the latest chess move in a sudden wave of big pharma dealmaking. The push has been driven by an industrywide slowdown in blockbuster drug development — as well as a need for large multinationals to do something with their hundreds of billions of dollars in overseas earnings. (Much of it can’t be repatriated without generating a huge tax bill.)

Below, Pfizer Chairman and CEO Ian Read weighs in on what he hopes to accomplish by meshing his $52 billion-in-revenues company with its U.K. rival. One thing’s for sure: If it happens, the $100 billion behemoth would be the industry’s biggest company ever.

Fortune: Why AstraZeneca and why now?

Read: AstraZeneca (AZN) is a wonderful portfolio match with our portfolio. It has tremendous strength in inflammation, a good oncology presence, and a good position in diabetes. And we can be far more productive if you look at the match with the established products unit by leveraging the network in emerging markets and elsewhere. That’s of critical importance to us. There are a lot of overlaps in science being done, and the secular trend is that the industry will continue to consolidate by the type of deal we’re doing, or by an exchange of assets.

What’s in it for AstraZeneca, other than the share price premium? Have there been any formal discussions yet?

They’re a new management team, and clearly they are good people and they’ve got a focused vision. I think they need to be convinced that the combination of the two [will work]. There have been no real discussions of substance other than “we’d like to do a deal.” We did give them an offer on the last day we had an undisturbed stock price (Jan. 3). Now [because of U.K. law] we have 28 days to decide [whether to make a formal offer]. There has been no direct response.

A lot of analysts and investors think this deal is motivated by tax benefits rather than strategic advantages, since you would use the inclusion strategy to get a U.K.-based tax treatment. Is this true?

I’ve been very clear that the origin of this deal is the combination of the two companies, and the science and the ability to create great value for shareholders. Now when I look at that deal compared with what I would have to pay if I did it in the U.S., the negative [tax] synergies would kill the deal. There’s a 20% tax rate in the U.K., and here, because of dividend requirements, it would probably be a 38% tax rate. So to get the deal done we have to domicile in the U.K.

[Editor’s Note: After Fortune’s interview was posted online, Pfizer wrote to clarify that Read meant, “to get the deal done we have to domicile in the U.K. in order to not subject AstraZeneca’s non-US earnings to US tax.”]

When you look at a deal you look at three components: What are the possible revenue synergies, what are the cost synergies, and some deals also look at financial synergies. We have got all three components in our deal, and we don’t think any one is dominant.

It seems like Pfizer has been trying to get smaller, not bigger, of late, with its sales and spinoffs of nutritional health and animal health, respectively. Why the shift in strategy?

When I took over (in late 2010), I said we’re a pharmaceutical company and we have got to fix the innovative core and get capital allocation right. We haven’t gotten smaller in pharma. My discussion point has always been that size is not the relevant question. We just want to focus on what creates shareholder value. [Over my tenure] I have been trying to create this optionality, which we’ve discussed with the Street, that we’re going to give you transparency, and you’re going to be able to feed back to us through how you invest whether you believe we’re managing [our assets] well or if they would be better managed separately.

Every Pfizer CEO of the past two decades has done an enormous, industry-changing merger (Warner-Lambert in 2000, Pharmacia in 2002, Wyeth in 2009). Is this one meant to be your legacy?

I think if you look at the deals, each was caused by different circumstances. Warner-Lambert was driven by the [patent expiry] of Lipitor and seeing that share taken away. [Editor’s Note: Pfizer later clarified that the Warner-Lambert deal was driven by Pfizer’s desire to acquire “the exclusive rights” of Lipitor.] The Pharmacia deal was more about the pain franchise. As a concept it worked. The specialty businesses we got were wonderful businesses, but we had a Bextra problem [like Merck’s Vioxx, it was withdrawn from the market after negative side effects were reported; in 2009 Pfizer paid $2.3 billion in a civil and criminal fine for illegal marketing of Bextra and other drugs]. The Wyeth deal was a deal about technology, about getting into large molecules and vaccines and about cost synergies. That was a trifecta. This one is too.

About the Author
By Jennifer Reingold
See full bioRight Arrow Button Icon

Latest in Finance

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Fortune Secondary Logo
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • World's Most Admired Companies
  • See All Rankings
  • Lists Calendar
Sections
  • Finance
  • Fortune Crypto
  • Features
  • Leadership
  • Health
  • Commentary
  • Success
  • Retail
  • Mpw
  • Tech
  • Lifestyle
  • CEO Initiative
  • Asia
  • Politics
  • Conferences
  • Europe
  • Newsletters
  • Personal Finance
  • Environment
  • Magazine
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
  • Group Subscriptions
About Us
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Latest in Finance

Best private student loans for grad school in June 2026
Personal FinanceLoans
Best private student loans for grad school in June 2026
By Joseph HostetlerJune 8, 2026
9 hours ago
AXA launches a new insurance and wealth platform for HNWIs as Hong Kong wealth surges past Switzerland
AsiaAXA
AXA launches a new insurance and wealth platform for HNWIs as Hong Kong wealth surges past Switzerland
By Nicholas GordonJune 8, 2026
9 hours ago
Child struggling with schoolwork
EconomyEducation
70% of fourth-graders aren’t reading proficiently, report finds—one of several areas where education is failing America’s kids
By Tristan BoveJune 8, 2026
11 hours ago
The global airline industry’s profits could be cut in half as it braces for its worst year since the pandemic
EnergyAirline industry
The global airline industry’s profits could be cut in half as it braces for its worst year since the pandemic
By Marco Quiroz-GutierrezJune 8, 2026
11 hours ago
A trader works on the floor of the American Stock Exchange (AMEX) at the New York Stock Exchange (NYSE) in New York, US, on Friday, June 5, 2026.
InvestingWall Street
The AI trade’s worst day in a year became a buying opportunity by Monday
By Eva RoytburgJune 8, 2026
13 hours ago
Young people working in an office.
EconomyGen Z
Gen Z might be the flakiest generation when it comes to career and life decisions. They might also be the most intentional
By Tristan BoveJune 8, 2026
14 hours ago

Most Popular

'We didn’t see this coming': Wall Street eats its forecasts as stocks sell off globally on fear of AI bubble ahead of SpaceX IPO
Economy
'We didn’t see this coming': Wall Street eats its forecasts as stocks sell off globally on fear of AI bubble ahead of SpaceX IPO
By Jim EdwardsJune 8, 2026
21 hours ago
Gen Zers are arriving at college unable to even read a sentence—professors warn it could lead to a generation of anxious and lonely graduates
Success
Gen Zers are arriving at college unable to even read a sentence—professors warn it could lead to a generation of anxious and lonely graduates
By Preston ForeJune 7, 2026
2 days ago
Trump, who has repeatedly called climate change fake, is now threatening Brazil with tariffs over the deforestation of the Amazon
Environment
Trump, who has repeatedly called climate change fake, is now threatening Brazil with tariffs over the deforestation of the Amazon
By Sasha RogelbergJune 8, 2026
10 hours ago
'The golden years are not golden': Boomers are hoarding most of America's wealth and power because they're terrified of outliving their money
Economy
'The golden years are not golden': Boomers are hoarding most of America's wealth and power because they're terrified of outliving their money
By Nick LichtenbergJune 7, 2026
2 days ago
Current price of oil as of June 8, 2026
Personal Finance
Current price of oil as of June 8, 2026
By Joseph HostetlerJune 8, 2026
17 hours ago
SpaceX's IPO will also be a massive selling event triggering big price dislocations across the stock market as investors dump shares to buy SPCX
Investing
SpaceX's IPO will also be a massive selling event triggering big price dislocations across the stock market as investors dump shares to buy SPCX
By Jason MaJune 7, 2026
1 day ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.