• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia

Trendingnow

1

Mark Cuban says he has the solution to growing income inequality, and it's to reward every employee—from CEO to janitor—with company stock

2

‘I want to die broke’: Billionaire philanthropist Denny Sanford dies after giving away $4 billion

3

'Dr. Doom' Nouriel Roubini says we're headed for universal basic income or 'some form of socialism' as AI revolutionizes work—He calls that optimistic

1

Mark Cuban says he has the solution to growing income inequality, and it's to reward every employee—from CEO to janitor—with company stock

2

‘I want to die broke’: Billionaire philanthropist Denny Sanford dies after giving away $4 billion

3

'Dr. Doom' Nouriel Roubini says we're headed for universal basic income or 'some form of socialism' as AI revolutionizes work—He calls that optimistic
SuccessFortune Intelligence

Legendary investor Vinod Khosla advises Gen Z to invest in this one skill because ChatGPT can teach you everything else

Nick Lichtenberg
By
Nick Lichtenberg
Nick Lichtenberg
Business Editor
Down Arrow Button Icon
Nick Lichtenberg
By
Nick Lichtenberg
Nick Lichtenberg
Business Editor
Down Arrow Button Icon
August 4, 2025, 2:08 PM ET
Vinod Khosla
Vinod Khosla believes that in years to come, an AI should theoretically be able to perform even heart or brain surgery to a high level.Steven Ferdman/Getty Images
Add Fortune on Google for similar content.

In a candid and far-reaching discussion on Nikhil Kamath’s YouTube channel, legendary venture capitalist Vinod Khosla, one of Fortune’s most powerful people in business, delivered some advice for Gen Z. It could be seen as a stark warning or as simple pragmatism: The single most important skill for young workers at this moment is not specialization, but the ability to learn rapidly and adapt continuously. His reasoning is simple yet profound: “ChatGPT can teach you any new areas,” rendering traditional academic paths and fixed skill sets increasingly obsolete. The title of the episode was more blunt: “College Degrees Are Becoming Useless.”

Recommended Video

The Sun Microsystems cofounder, known for his contrarian views and unwavering certainty in technological possibilities, painted a future where artificial intelligence (AI) will fundamentally transform the job market. He asserted that “there isn’t a job where AI won’t be able to do 80% of 80% of all jobs” within the next three to five years. He explained that the vast majority of all job functions will be replicable by AI, hence the 80% of 80% estimate. It recalled Sam Altman’s claim that AI will result in “intelligence too cheap to meter.”

Looking 10 to 15 years out, Khosla said, he believes “there’s no chance there’s a job that humans do that AI can’t do almost as well.” He allowed for some minor exceptions and said even heart or brain surgery an AI should theoretically be able to perform to a high level, although regulation may not allow it. This rapid pace of change, faster than the world has seen in the past 50 years, demands a radical shift in how young people approach their careers, he argued.

For a 22-year-old wondering where to focus their efforts, Khosla’s advice is clear: “You have to optimize your career for flexibility, not a single profession.” He emphasized that the value of learning lies not in mastering one specific trade like welding, finance, or even accounting, but in cultivating “the ability to learn” in its own right. He claimed that at 70 years old, he is learning at a much faster pace than ever before, and every young person should strive for this capability. This includes thinking from first principles and jumping into diverse fields, whether physics, biology, or finance, because AI tools will facilitate the rapid acquisition of new knowledge.

Khosla argued that even disciplines like computer science are valuable less for programming expertise (which AI increasingly handles) and more for the “process of thinking” and understanding systems and architectures they impart. The ultimate goal for a young individual, he suggests, is to choose a path where “your knowledge compounds and your capability compounds over time,” mirroring the principle of financial compounding in knowledge acquisition.

The quality of the entrepreneur

For aspiring entrepreneurs, Khosla advises a strategic focus, since he believes that anybody in any industry not using AI will be rendered obsolete by somebody who is using the tool. While AI may democratize technology, he said, success will hinge on the innate “quality of the entrepreneur”—their ability to think strategically, envision long-term goals, select the right teams, and wisely choose who to trust for advice. Khosla believes the current shortage is not of technology or capital, but of “great entrepreneurs who know how to make these choices.”

Beyond individual careers, Khosla and Kamath talked about the wider implications of AI on the economy. Khosla said it should drive down the cost of many things, acting as a deflationary force on many services, and he envisioned an AI-powered utopian future where services like education, medical expertise, and legal advice become “almost free.” He speculated that in 20 to 25 years, $10,000 might buy more goods and services than $50,000 does today, thanks to the deflationary impact of machines providing abundant services.

The career path open to Gen Z

Khosla is far from the only thought leader weighing in on the employment prospects for Gen Z in the age of AI. Anthropic CEO Dario Amodei and Nvidia CEO Jensen Huang have engaged in an ever-more-heated war of words over the former’s doomsday prediction that 50% of all white-collar jobs will be wiped out. Geoffrey Hinton, the “godfather of AI,” has largely agreed with Amodei, saying that only the “very skilled” will remain employed. Huang and Federal Reserve chair Jerome Powell have largely agreed with Khosla, arguing that creativity and constant learning will create new jobs for the economy in a virtuous cycle.

Goldman Sachs chief economist Jan Hatzius has looked at the data and echoed Khosla’s argument that college degrees are losing value, finding that the “safety premium” of a college degree is disappearing. Berkeley economist Brad DeLong agrees that the college degree is losing its status but casts the blame away from AI and toward the policy uncertainty plaguing the economy, arguing that many Gen Z college graduates are going unhired because conditions are just too risky for most companies. Goldman seems to agree with DeLong, finding in July that AI was overhyped as a reason for most corporate layoffs. Meanwhile, the Federal Reserve isn’t completely sold on the revolutionary prospects of AI, arguing that it may be a revolutionary invention like the electric dynamo, but may end up being a one-off boost to productivity, like the light bulb.

Gen Z, for its part, seems to be craving more human connection. Starbucks recently announced it would sunset its mobile-only locations, thought to be more appealing to Gen Z and a desire for “frictionless” experience, in favor of a renewed emphasis on hospitality and human-to-human connection. The generation has been weathering criticism of late that they lack the social skills necessary for success, with the stereotypical “Gen Z stare” at the center of the conversation. Careers site Glassdoor, for its part, has punctured the myth of “conscious unbossing” by Gen Zers, finding that they are becoming managers at exactly the same historical rate as any other generation, AI notwithstanding.

Ultimately, Khosla’s message for the next generation is one of relentless pursuit of learning and adaptability. In a world rapidly being reshaped by AI, the ability to continuously reinvent oneself and embrace new knowledge may be the ultimate differentiator for survival and success. The human capacity to learn new things, after all, is endless.

For this story, Fortune used generative AI to help with an initial draft. An editor verified the accuracy of the information before publishing. 

The Fortune 500 Innovation Forum will convene Fortune 500 executives, U.S. policy officials, top founders, and thought leaders to help define what’s next for the American economy, Nov. 16-17 in Detroit. Apply here.
About the Author
Nick Lichtenberg
By Nick LichtenbergBusiness Editor
LinkedIn icon

Nick Lichtenberg is business editor and was formerly Fortune's executive editor of global news.

See full bioRight Arrow Button Icon
Add Fortune on Google for similar content.

Latest in Success

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Fortune Secondary Logo
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • World's Most Admired Companies
  • See All Rankings
  • Lists Calendar
Sections
  • Finance
  • Fortune Crypto
  • Features
  • Leadership
  • Health
  • Commentary
  • Success
  • Retail
  • Mpw
  • Tech
  • Lifestyle
  • CEO Initiative
  • Asia
  • Politics
  • Conferences
  • Europe
  • Newsletters
  • Personal Finance
  • Environment
  • Magazine
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
  • Group Subscriptions
About Us
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • TikTok icon
  • YouTube icon

Latest in Success

Cleveland’s WNBA team doesn’t play until 2028 but Progressive just scored jersey sponsorship
SuccessSports
Cleveland’s WNBA team doesn’t play until 2028 but Progressive just scored jersey sponsorship
By Joe Reedy and The Associated PressJuly 21, 2026
2 hours ago
Lauren Sánchez Bezos put $34 million behind reinventing what clothes are made of—and stirred a debate about Amazon
Environmentphilanthropy
Lauren Sánchez Bezos put $34 million behind reinventing what clothes are made of—and stirred a debate about Amazon
By Sydney LakeJuly 21, 2026
4 hours ago
Jamie Dimon says insecurity, not ego, is what destroys the careers of top CEOs
C-SuiteJamie Dimon
Jamie Dimon says insecurity, not ego, is what destroys the careers of top CEOs
By Marco Quiroz-GutierrezJuly 21, 2026
5 hours ago
Two students stand next to each other and look at the papers they are holding.
AIEducation
Study finds AI boosted homework scores 18%—then tanked exam results 20%
By Sasha RogelbergJuly 21, 2026
7 hours ago
math
AIScience
Mathematicians grapple with a ‘very rapid and very unsettling change’ as AI cracks yet another century-old problem
By Eva RoytburgJuly 21, 2026
7 hours ago
Welder on a navy boat
SuccessCareers
Jamie Dimon says six-figure shipyard jobs are the new ‘American Dream’—but candidates will need to endure hours of extreme heat, cold, and rain
By Preston ForeJuly 21, 2026
8 hours ago

Most Popular

Mark Cuban says he has the solution to growing income inequality, and it's to reward every employee—from CEO to janitor—with company stock
Success
Mark Cuban says he has the solution to growing income inequality, and it's to reward every employee—from CEO to janitor—with company stock
By Sasha RogelbergJuly 20, 2026
1 day ago
‘I want to die broke’: Billionaire philanthropist Denny Sanford dies after giving away $4 billion
Success
‘I want to die broke’: Billionaire philanthropist Denny Sanford dies after giving away $4 billion
By Sydney LakeJuly 20, 2026
1 day ago
'Dr. Doom' Nouriel Roubini says we're headed for universal basic income or 'some form of socialism' as AI revolutionizes work—He calls that optimistic
AI
'Dr. Doom' Nouriel Roubini says we're headed for universal basic income or 'some form of socialism' as AI revolutionizes work—He calls that optimistic
By Jason MaJuly 18, 2026
3 days ago
The Treasury is walking a tightrope on U.S. debt by relying so much on short-term rates that are at the mercy of a suddenly very hawkish Fed
Economy
The Treasury is walking a tightrope on U.S. debt by relying so much on short-term rates that are at the mercy of a suddenly very hawkish Fed
By Jason MaJuly 20, 2026
1 day ago
Current price of silver as of Monday, July 20, 2026
Personal Finance
Current price of silver as of Monday, July 20, 2026
By Joseph HostetlerJuly 20, 2026
2 days ago
Jamie Dimon won't put more of his own money into the long end of the bond market right now—thanks to the $39 trillion national debt
Economy
Jamie Dimon won't put more of his own money into the long end of the bond market right now—thanks to the $39 trillion national debt
By Eleanor PringleJuly 21, 2026
13 hours ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.