• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
NewslettersThe Capsule

The last mile of the immunization campaign approaches

By
Sy Mukherjee
Sy Mukherjee
and
David Z. Morris
David Z. Morris
Down Arrow Button Icon
By
Sy Mukherjee
Sy Mukherjee
and
David Z. Morris
David Z. Morris
Down Arrow Button Icon
April 21, 2021, 5:03 PM ET

Good afternoon, readers.

An immunization campaign against a virus evolves just as a pathogen itself does. First, you need to make the product. Then, you need to ramp up supply and delivery systems to get shots into arms. But the next step comes with a whole different set of tactics.

You see, we’re about two weeks to one month away from the COVID vaccine supply-and-demand curve reversing itself. In other words: The U.S. will soon reach the point when the public’s demand and enthusiasm for a vaccine starts to lag behind a glut of supply rather than the other way around, according to a new report from the think tank Kaiser Family Foundation.

That’s due to a number of factors. For one thing, vaccine eligibility has ramped up considerably, with all American adults 16 and over eligible since the beginning of this week. The brand new distribution systems and partnerships necessitated by the pandemic have also become more stable, although there are still plenty of production hiccups and inequities that will be critical to track.

But the fact is that more than 86 million Americans have already been fully vaccinated against COVID, according to the Centers for Disease (CDC). That number climbs to more than 133 million when including those who have received at least one shot.

The clip of vaccinations, however, already appears to be falling. And that presents the next major challenge – convincing the roughly 20% of adults who are most ardently opposed to vaccination to get a shot so that we can truly achieve herd immunity.

“Federal, state, and local officials, and the private sector, will face the challenge of having to figure out how to increase willingness to get vaccinated among those still on the fence, and ideally among the one-fifth of adults who have consistently said they would not get vaccinated or would do so only if required,” writes KFF in its report.

We’ll find out soon enough which tactics work the best in that undertaking.

Read on for the day’s news.

Sy Mukherjee
sy.mukherjee@fortune.com
@the_sy_guy

DIGITAL HEALTH

Alexa, where can I get a COVID vaccine? Amazon announced on Wednesday that its Alexa-compatible devices can now assist users in finding COVID vaccination sites. "Alexa, where can I get a COVID vaccine?" is the question and Amazon's tech, which can also direct owners to call nearby vaccination sites to check on appointment availabilities, provides the answer. It's unclear just how effective it is given that some appointment-setting sites, depending on where you live, might be a bit of a mess. But given Alexa's vast user network, it's a feature that may be used on a wide scale before the vaccine supply-demand dynamic flips.  (The Verge)

INDICATIONS

The slow-but-steady turnaround on J&J's COVID vaccine. With continuing caution over (extremely rare) blood clots associated with Johnson & Johnson's and AstraZeneca's COVID vaccines, European regulators are still recommending that these shots (and Johnson & Johnson's specifically) continue to be used. While noting the possible link between the J&J jab and blood clots in a tiny slice of the population, the European Medicines Agency (EMA) pointed out COVID is still the bigger threat. "COVID-19 is associated with a risk of hospitalization and death. The reported combination of blood clots and low blood platelets is very rare, and the overall benefits of COVID-19 Vaccine Janssen in preventing COVID-19 outweigh the risks of side effects,” the agency said. Johnson & Johnson announced it will resume sending vaccine doses to Europe following the guidance. (Fortune)

THE BIG PICTURE

Big Soda continues to show its clout. The soda pop and sugary drinks industry notched another win as California legislators shelved a proposal to undo a 2018 agreement, largely manufactured by the beverage industry, that would prevent the taxation of high-sugar beverages. Kaiser Health News reports that the beverage industry, including giants such as Pepsi and Coca-Cola, spent $5.9 million over the past four years lobbying legislators in the Golden State, and had donated to causes supported by nearly every lawmaker and state official. (Kaiser Health News)

REQUIRED READING

A tour inside the post-pandemic gym, by Rachel King

Carbon emissions are going to balloon post-COVID, by Sophie Mellor

LinkedIn adds more caretaker titles as women leave the workforce, by Maria Aspan

About the Authors
By Sy Mukherjee
See full bioRight Arrow Button Icon
By David Z. Morris
See full bioRight Arrow Button Icon

Latest in Newsletters

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Fortune Secondary Logo
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • Future 50
  • World’s Most Admired Companies
  • See All Rankings
Sections
  • Finance
  • Fortune Crypto
  • Features
  • Leadership
  • Health
  • Commentary
  • Success
  • Retail
  • Mpw
  • Tech
  • Lifestyle
  • CEO Initiative
  • Asia
  • Politics
  • Conferences
  • Europe
  • Newsletters
  • Personal Finance
  • Environment
  • Magazine
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
  • Group Subscriptions
About Us
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
Fortune Secondary Logo
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Latest in Newsletters

NewslettersCIO Intelligence
Lenovo’s CIO says patience is a virtue in AI investing, but the clock is ticking
By John KellMarch 4, 2026
45 minutes ago
NewslettersMPW Daily
What Jasmine Crockett’s loss says about race, gender, and electability in Democratic politics
By Emma HinchliffeMarch 4, 2026
2 hours ago
Colleagues at business meeting in conference room
NewslettersCFO Daily
Finance leaders are divided on how they’d use potential tariff refunds—with just 18% saying they’d fully roll back price increases
By Sheryl EstradaMarch 4, 2026
5 hours ago
NewslettersTerm Sheet
The French AI startup gunning for Workday, Oracle, and SAP
By Lily Mae LazarusMarch 4, 2026
6 hours ago
Fortune Editor-in-Chief Alyson Shontell and Khosla Ventures Founder Vinod Khosla: Graphic for Fortune 500 Titans and Disruptors of Industry podcast. Episode title: "AI and the end of work?"
NewslettersCEO Daily
Famed investor Vinod Khosla predicts free AI labor will lead to an era of few jobs and great abundance
By Alyson ShontellMarch 4, 2026
7 hours ago
NewslettersFortune Tech
The curious case of Nvidia’s employee stock compensation change-up
By Alexei OreskovicMarch 4, 2026
7 hours ago

Most Popular

placeholder alt text
Economy
Interest on the $38.8 trillion national debt has tripled since 2020, and it already costs taxpayers more than defense and Medicaid
By Nick LichtenbergMarch 2, 2026
2 days ago
placeholder alt text
Personal Finance
Current price of silver as of Tuesday, March 3, 2026
By Joseph HostetlerMarch 3, 2026
1 day ago
placeholder alt text
Real Estate
Meet a burned out 28-year-old who pays $168 a month in China's faux Venice to retire early from her Shanghai finance gig
By Albee Zhang and The Associated PressMarch 2, 2026
2 days ago
placeholder alt text
Cybersecurity
Cities join Amazon in cutting ties with license-plate reader Flock following Ring's Super Bowl ad—that Flock 'didn't have anything to do with'
By Catherina GioinoMarch 3, 2026
23 hours ago
placeholder alt text
Middle East
Iran’s Islamic Revolutionary Guard controls a sprawling business empire that dominates the economy
By Jason MaMarch 2, 2026
2 days ago
placeholder alt text
Personal Finance
Current price of gold as of March 3, 2026
By Danny BakstMarch 3, 2026
1 day ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.