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Brainstorm Health: Theranos and Hype, Emergency Care Drones, FDA Vs Nicotine

March 15, 2018, 8:32 PM UTC

Happy Thursday. Yesterday, the Securities and Exchange Commission reached a settlement with Elizabeth Holmes, the turtleneck-togged founder of the once-darling of the startup set, Theranos, after alleging that she and another Theranos executive had engaged in an “elaborate, years-long fraud in which they exaggerated or made false statements about the company’s technology, business, and financial performance.” (Holmes, who agreed to pay a $500,000 fine, forfeit shares, and give up voting control of Theranos, did not admit or deny the allegations; there is also an ongoing federal criminal probe into the company.)

(I urge all of you to read not just Carreyrou’s reporting series, but also Roger’s candid and reflective essay, from December 2015, which laid out how the company had misled him—and, more importantly, how he had misled himself. Roger’s essay, in my view, is a testament to his great character; it’s also a glimpse into how difficult it can be to report on companies and new technologies, especially in an age when advances are coming so swiftly.)

Carreyrou, to his great credit, managed to pierce the wall of secrecy that Holmes had constructed around her startup—a secrecy that is particularly common in health, science, and medtech startups, in my experience. [My colleague Polina Marinova has an excellent essay on the subject in Fortune’s Term Sheet today (“The Big Lesson Silicon Valley Can Learn From the Theranos Scandal”), which you can also read here.]

And to be sure, the sad Theranos saga is a sobering reminder of how essential a healthy skepticism and due diligence are when it comes to evaluating companies—particularly those that are secretive or excessively cryptic about the technologies they’re hawking.

But that said, skepticism is not the same thing as cynicism. And this may sound odd, admittedly, given yesterday’s Theranos news, but I would argue that we need a little hype now and again in the startup world—just as the human body sometimes needs a rush of adrenaline. Maybe not “hype” in the sense that many think of it (and as Merriam-Webster defines it): a “deception” or “put-on”—but rather as the technology research firm Gartner uses the term in its annual and widely read “Hype Cycle for Emerging Technologies.”

Each year, Gartner’s Hype Cycle, highlights “a set of technologies that will have broad-ranging impact across the business…It features technologies that are the focus of attention because of particularly high levels of hype, or those that may not be broadly acknowledged but that Gartner believes have the potential for significant impact.”

Read through old Hype Cycle reports—like this one from 2011—and you’ll see that many of the technologies then considered at “the Peak of Inflated Expectations” seven years ago, according to Gartner, are technologies that are actually coming of age today, including:

… wireless power, Internet TV, NFC payment and private cloud computing. Other newly featured high-impact trends include “big data,” the Internet of Things and natural language question answering.

Invention—as brilliant as it may be—dies without adoption. Adoption often fails without continued investment. Investment often follows vision. And vision needs to be shared and promoted…and, yes, sometimes hyped in order to find an audience amid all of the other competing visions, investments, and inventions.

Be skeptical—absolutely—when someone is telling you they’re changing the world. But don’t dismiss everyone out of hand who claims they are. Otherwise, the world will miss out on some pretty outlandish world-changing ideas—from autonomous vehicles to cancer-fighting checkpoint inhibitors to smartphones that can warn of an impending stroke to deep-learning machines that may solve some of the biggest mysteries in human disease. All of these were far-fetched, and thankfully, promoted by true believers.

To paraphrase Gordon Gekko, a little hype is good.

Clifton Leaf, Editor in Chief, FORTUNE


Drones for emergency care? New York-based health system Northwell Health is looking to the skies (with the help of drone technology) for possibly deploying digital health care in emergency situations like an opioid overdose or national security catastrophe, Northwell chief technology officer Purna Prasad tells FierceHealthcare. “This is actually our next foray into telehealth,” he told the publication. “There may be places where there is no network connection, or there maybe be places where people just don’t have the wherewithal to have any type of mobile phone for two-way video conferencing. Can the drone provide that last mile of connectivity not only for audio, video and data, but also in delivering emergency care?” (FierceHealthcare)


Adaptimmune shares soar on cancer trial results. Shares of biotech Adaptimmune soared 20% or more in Thursday trading after the company announced strong clinical study results for a new kind of cancer treatment. Adaptimmune is developing so-called T-cell therapies that recruit the body's immune system to fight tumors—and, strikingly, the treatment is showing early promise in fighting solid tumors. The company is also partnered with pharma giant GlaxoSmithKline on a drug program.


The FDA continues its blitz on nicotine. Food and Drug Administration (FDA) Commissioner Scott Gottlieb is continuing an anti-nicotine effort he launched last year, when his agency declared that it would fight to make tobacco products less harmful by attempting to slash nicotine levels. The FDA now wants to set a maximum nicotine level in both cigarettes and other tobacco products in an effort to stem addiction. (Reuters)


The Big Lesson Silicon Valley Can Learn From the Theranos Scandalby Polina Marinova

How Debt Could Blow Up the Trump Economyby Shawn Tully

NCAA Basketball Is Huge Business. Here's Who's Making the Most Cashby Christina Austin

IBM Strikes Partnership to Take on Amazonby Robert Hackett

Produced by Sy Mukherjee

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