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Brainstorm Health: Tiny Killers, OxyContin Marketing, Flu Season Update

February 12, 2018, 3:54 PM UTC

Happy Monday, Dailies. What do an Olympic outbreak of norovirus in Pyeongchang, a death from Lassa fever in Guinea, and a severe eruption of flu in the United States have in common? Each—in addition to happening right now (or very recently)—is a reminder of how frail the human organism can be compared with the microorganisms that compete with us for earthly dominance.

The recent Lassa fever death in Guinea—the first in more than two decades, as the Washington Post notes—is worrisome for a number of reasons, but one of those is where the Guinean victim died: next door in Liberia. The cross-border fatality conjures up bad memories of another hemorrhagic fever, Ebola, which freely crossed borders in the horrific 2014 West African outbreak. (Also raising concern is how long it apparently took health officials to publicly report the death. The infected person died nearly a month ago, on Jan. 11.)

And the flu? Its power to sicken and kill is made clear year after year after year—and still we seem surprised by its morbid rage…year after year after year.

These little invisible beasts—whether they be RNA-based noroviruses, arenaviruses like Lassa, or influenza viruses—evolve as we do…only much, much faster. And many of them are world travelers to boot, collecting frequent flier miles as if they were globetrotting CEOs.

For those curious and intrepid, the NIH has a handy manifest of Emerging Infectious Diseases, or EIDs, which it breaks down into three categories, based on the priority of the threat.

The scariest of these EIDs, from a population health standpoint, aren’t the ones that kill the most, but rather the ones that get lots of people pretty darn sick. The pathogens on this list also disseminate with moderate ease and, say health officials, “require specific enhancements for diagnostic capacity” in order to identify them rapidly—a level of readiness we simply don’t have for many new infectious diseases.

Why do I bring this up on a beautiful Monday morning? To remind us that we—and I speak here of both the American “we” and the global “we”—don’t yet have a good defensive plan to deal with these threats. The nightly news reports about the brutal seasonal flu, now widespread across our great land, haven’t jumpstarted efforts to build (and fund) such a plan.

And if that hasn’t done it—and if Zika and Ebola and SARS didn’t do it before that—I don’t want to imagine what will.

Clifton Leaf, Editor in Chief, FORTUNE


A video game helps calm schizophrenia patients. A small pilot study of schizophrenia patients found that a particular video game where the user has to land a rocket helped the patients control verbal hallucinations. The study participants were asked to develop strategies for landing the rocket mentally; this, in turn, allowed the patients to strategize ways of blocking out hallucinatory voices inside their heads. (BBC)


David Hung exits Axovant after Alzheimer's debacle. Axovant shares tumbled another 20% Monday after CEO David Hung, the former chief of Medivation who orchestrated the latter company's sale to Pfizer, resigned from the post after less than a year on the job. Axovant had a devastating setback in its Alzheimer's drug program last year, leading industry observers to question whether parent company Roivant's unusual approach to drug development will yield substantial successes any time soon. (Nasdaq)

OxyContin manufacturer's marketing rollback. OxyContin maker Purdue Pharma will no longer market its powerful, flagship opioid to doctors, a marked reversal precipitated by the opioid painkiller addiction and overdose crisis. The company will also cut its U.S. sales staff in half—but, given Purdue's prominent role in boosting OxyContin as a pain treatment, some public health experts are questioning whether the move comes too late. (Fortune)


The flu's killing 4,000 Americans per week. Just how bad is this year's flu season? It's killing up to 4,000 Americans every week, according to the Centers for Disease Control (CDC). The flu season is now likely on pace to claim even more lives than the 2009-2010 swine flu epidemic, and officials say it will linger for weeks to come. (Fortune)


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Produced by Sy Mukherjee

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