Natera, a San Carlos, Calif.-based provider of a non-invasive prenatal genetics test, has raised $54.6 million in new VC funding. OrbiMed Advisors and Harmony Partners co-led the round, and were joined by return backers Claremont Creek Ventures, Lightspeed Venture Partners, Founders Fund and Sequoia Capital. www.natera.com
Dwolla, a Des Moines, Iowa-based digital wire transfer service, has raised around $16.5 million in Series C funding. Andreessen Horowitz led the round, and was joined by return backers Village Ventures, Thrive Capital, and Union Square Ventures. www.dwolla.com
VMTurbo, a Burlington, Mass.-based provider of software-defined control for cloud and virtualized environments, has raised $7.5 million in Series C funding. Globespan Capital led the round, and was joined by return backers Bain Capital Ventures and Highland Capital Partners. www.vmturbo.com
Curious, a matching platform for teachers and learners, has raised $7.5 million in VC funding.Redpoint Ventures led the round, and was joined by Curious founder Justin Kitch (whose last venture, Homestead, was acquired by Intuit for $170 million). www.curious.com
Pixability, a Cambridge, Mass.-based online video marketing company, has raised $4.1 million in new VC funding led by Quad/Graphics Inc. (NYSE: QUAD). Progress Partners served as placement agent.www.pixability.com
MindMixer, an Omaha-based online engagement platform for civic, education and healthcare organizations, has raised $4 million in new VC funding. Nelnet led the round, and was joined by return backers Dundee Venture Capital and Optimas Group. www.mindmixer.com
Workspot, a Menlo Park, Calif.-based bring-your-own-device solution for the mobile workplace, has raised $1.9 million in seed funding. Backers include Kleiner Perkins Caufield & Byers, Norwest Venture Partners, Redpoint Ventures, Peter Wagner and Gaurav Garg. www.workspot.com
Leap2, a Kansas City-based search platform that incorporates real-time social and local context, has raised $1.6 million in VC funding. Dundee Venture Capital led the round, and was joined by OpenAir Equity, Linseed Capital and Wichita Technology Corp. www.leap2search.com
AnTech Ltd., a UK-based developer of directional coiled tubing drilling products and services, has raised an undisclosed amount of VC funding from Saudi Aramco Energy Ventures and Calculus Capital. www.aramcoventures.com
Expect Labs, a San Francisco-based platform for powering “intelligent digital assistants,” has raised an undisclosed amount of VC funding from Intel Capital, Samsung Venture Investment Corp. andTelefonica Digital. www.expectlabs.com
Sign up for Dan’s daily email newsletter on deals and deal-makers: GetTermSheet.com