• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia

Trendingnow

1

'Dr. Doom' Nouriel Roubini says we're headed for universal basic income or 'some form of socialism' as AI revolutionizes work—He calls that optimistic

2

Power companies are using eminent domain to seize land for data centers as 70% of Americans say not in my backyard

3

Red Lobster’s 37-year-old CEO waited tables before joining the C-suite—he says it was a crash course in managing ‘difficult people and situations’

1

'Dr. Doom' Nouriel Roubini says we're headed for universal basic income or 'some form of socialism' as AI revolutionizes work—He calls that optimistic

2

Power companies are using eminent domain to seize land for data centers as 70% of Americans say not in my backyard

3

Red Lobster’s 37-year-old CEO waited tables before joining the C-suite—he says it was a crash course in managing ‘difficult people and situations’
HealthVaccines

Polio is a deadly disease with a vaccine that RFK Jr.’s adviser wants to ban. Here’s how the immunization works

By
Lindsey Leake
Lindsey Leake
Down Arrow Button Icon
By
Lindsey Leake
Lindsey Leake
Down Arrow Button Icon
December 13, 2024, 4:30 PM ET
The polio vaccine has all but obliterated the illness that once killed thousands and paralyzed 15,000 people nationwide every year.
The polio vaccine has all but obliterated the illness that once killed thousands and paralyzed 15,000 people nationwide every year.Marina Demidiuk—Getty Images
Add Fortune on Google for similar content.

There’s a reason you rarely hear about people catching polio—let alone dying from the highly infectious disease—particularly in the U.S. And if you’re under the age of 70, you’ve likely never had to live in fear of acquiring it yourself. The polio vaccine has all but obliterated the illness that once killed thousands and paralyzed 15,000 people nationwide every year.

Recommended Video

The above statistic hails from the Department of Health and Human Services (HHS), the agency President-elect Donald Trump has chosen outspoken vaccine skeptic Robert F. Kennedy Jr. to run. When the once and future commander-in-chief announced his HHS pick on X on Nov. 14, he wrote, “The Safety and Health of all Americans is the most important role of any Administration,” and that Kennedy would help “end the Chronic Disease epidemic.” Trump also said public health has suffered from the “deception, misinformation, and disinformation” of pharmaceutical companies.

Vaccine disinformation is rampant anew as it’s come to light that an advisor of Kennedy’s petitioned the Food and Drug Administration (FDA) to rescind its approval of the polio vaccine. The New York Times reported Dec. 13 that attorney Aaron Siri has been helping Kennedy vet candidates for top HHS jobs, a process that has included uncovering their vaccine views. Siri took to X later that afternoon to call the Times article a “hit piece” that “stokes fear,” and stressed that “assuring the safety of these injections is critical.”

The website of Siri & Glimstad LLP touts Siri as a managing partner who has fielded high-profile vaccine injury and policy cases, including “extensive litigation against federal agencies for transparency.” The law firm claims its clients have been awarded more than $5.2 billion in vaccine injury compensation.

In 2022, Siri filed the FDA petition on behalf of the nonprofit Informed Consent Action Network, alleging clinical trials of the polio vaccine weren’t rigorous enough to confirm its safety. The petition says the FDA “could not have fulfilled its statutory duty to assure the safety of [the vaccine] prior to licensing it for injection into infants, toddlers, and children.” Fortune 500 Europe company Sanofi manufactures the polio vaccine cited in the petition; head of vaccines Ayman Chit told the Times that the vaccine has undergone hundreds of studies, including safety follow-ups as long as six months.

Trump told TIME last month he planned to “have a big discussion” about childhood vaccination programs with Kennedy, who “does not disagree with vaccinations, all vaccinations.”

Is the polio vaccine safe?

While an oral polio vaccine (OPV) is administered in some countries, inactivated polio vaccine (IPV) has been the only available form of immunization in the U.S. since 2000. It’s not only safe but also effective. According to the Centers for Disease Control and Prevention (CDC), two doses of IPV provide at least 90% protection, while three doses offer at least 99% protection.

The risks and possible side effects of the polio vaccine are comparable to those of other vaccines, the CDC says, such as pain, soreness, swelling, and/or redness at the injection site. Fainting and dizziness are also possible. More serious reactions, including allergic reactions, are rare.

Three billion children have been vaccinated against polio since 1988, according to the Global Polio Eradication Initiative, meaning 20 million people who would’ve otherwise been paralyzed by polio are walking today.

The vaccine has helped eradicate two of the three wild poliovirus strains, according to the World Health Organization (WHO). Types 2 and 3 were eradicated in 1999 and 2020, respectively. Type 1 remained endemic in only Pakistan and Afghanistan as of 2022.

What is polio?

Poliomyelitis, or polio, is a distinctly contagious illness caused by a virus called poliovirus. The virus targets the nervous system, which is why it sometimes triggers spinal and respiratory paralysis—and death.

Polio primarily infects children under 5 and has done so around the globe for millennia. According to WHO, children with “withered limbs,” a hallmark of the ailment, are shown using canes in ancient Egyptian images. British physician Michael Underwood documented the first known clinical description of polio in 1789, and German doctor Jakob Heine formally recognized the condition in 1840.

Polio was “the most feared disease in the world” throughout the late 19th and early 20th centuries, WHO says. It killed or paralyzed more than half a million people every year by the mid-20th century, and left many survivors with lifelong complications from wheelchairs to artificial respirators.

The first polio vaccine, developed by U.S. physician Jonas Salk, became available in 1955.

This 1955 file photo shows the first polio vaccine being shipped to Europe on an <a href="https://fortune.com/company/american-airlines-group/" target="_blank">American Airlines</a> plane.
This 1955 file photo shows the first polio vaccine being shipped to Europe on an American Airlines plane.
Universal History Archive/Universal Images Group/Getty Images

How does polio spread?

Polio typically spreads from person to person via fecal-oral transmission, according to the CDC, but it can also spread through a sick person’s respiratory droplets. You might catch it from touching a contaminated object and putting your fingers in your mouth, or simply being in close contact with someone who has polio. People carrying the virus can infect others for up to two weeks after symptoms appear, and asymptomatic people can still make others sick.

Though less common, polio can also circulate when people consume contaminated food or drink. Proper hand washing with soap and water is more important than ever when it comes to polio prevention, as the CDC notes alcohol-based hand sanitizers don’t kill poliovirus.

Wild poliovirus has been eradicated in the U.S., but an infected person traveling from abroad can spur an outbreak. Anyone not fully vaccinated against polio is susceptible to infection. In 2022, an unvaccinated man in New York contracted paralytic polio from community transmission; the CDC confirmed genetic sequencing had tied New York wastewater samples to those in London and Jerusalem.

What are the symptoms of polio?

While most people with polio are asymptomatic, according to the CDC, about 25% of patients will exhibit these flu-like symptoms, which last two to five days:

  • Fever
  • Headache
  • Nausea
  • Sore throat
  • Stomach pain
  • Tiredness

The flu-like symptoms may not seem too bad, but polio brings devastating complications for some. Up to 5% of polio patients develop meningitis, the inflammation of the tissues surrounding the brain and spinal cord, the CDC estimates. Up to 0.5% develop paralysis of or weakness in the arms and/or legs—and up to 10% of those paralyzed die.

Even people with mild infections can experience post-polio syndrome (PPS) decades later. Symptoms of this non-contagious disease include joint pain, muscle weakness, and mental and physical fatigue. Up to 40% of polio survivors get PPS, which begins 15 to 40 years after infection.

Seek emergency medical care if you suspect you or a loved one has developed polio symptoms.

How is polio treated?

No cure for polio exists, which is why medical and public health officials worldwide urge vaccination to prevent the illness. Polio survivors with muscle weakness may benefit from physical or occupational therapy.

If you grew up in the U.S., chances are you received your four IPV polio vaccine doses at these CDC-recommended ages:

  • 2 months
  • 4 months
  • 6–18 months
  • 4–6 years

If you’re unsure of your polio vaccination status, it’s not too late. The CDC recommends adults get three IPV doses, with the second one to two months after the first, and the third six to 12 months after the second.

For more on vaccines:

  • Yes, you can get the COVID, flu, and RSV vaccines at once. Here are the pros and cons
  • New COVID vaccines are here. What to know about latest shots in wake of nation’s biggest summer surge
  • New flu shots have arrived. Here’s the best time to get your annual vaccine
  • RSV can be deadly, especially for older adults. What to know about symptoms and the new vaccine
  • Pneumonia can be a deadly complication of COVID, the flu, and RSV: What to know about pneumococcal vaccination

Subscribe to Well Adjusted, our newsletter full of simple strategies to work smarter and live better, from the Fortune Well team. Sign up for free today.

About the Author
By Lindsey Leake
LinkedIn iconTwitter icon
See full bioRight Arrow Button Icon
Add Fortune on Google for similar content.

Latest in Health

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Fortune Secondary Logo
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • World's Most Admired Companies
  • See All Rankings
  • Lists Calendar
Sections
  • Finance
  • Fortune Crypto
  • Features
  • Leadership
  • Health
  • Commentary
  • Success
  • Retail
  • Mpw
  • Tech
  • Lifestyle
  • CEO Initiative
  • Asia
  • Politics
  • Conferences
  • Europe
  • Newsletters
  • Personal Finance
  • Environment
  • Magazine
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
  • Group Subscriptions
About Us
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Latest in Health

A decade after the ‘Godfather of AI’ said radiologists were obsolete, their salaries are up to $571K and demand is growing fast
AIthe future of work
A decade after the ‘Godfather of AI’ said radiologists were obsolete, their salaries are up to $571K and demand is growing fast
By Marco Quiroz-GutierrezJuly 19, 2026
23 hours ago
How United’s ‘premiumization’ strategy got passengers to swallow higher airfares without a fight
HealthAirline industry
How United’s ‘premiumization’ strategy got passengers to swallow higher airfares without a fight
By Phil WahbaJuly 19, 2026
1 day ago
Diarrhea-causing lettuce may have spread as wide as 27 states, Taylor Farms recall suggests
HealthFood and drink
Diarrhea-causing lettuce may have spread as wide as 27 states, Taylor Farms recall suggests
By Savannah Peters and The Associated PressJuly 18, 2026
2 days ago
Walmart removes four Taylor Farms salads as recalls spread
RetailFood and drink
Walmart removes four Taylor Farms salads as recalls spread
By Jaewon Kang, Jessica Nix, Fabiola Zerpa and BloombergJuly 18, 2026
2 days ago
Backstabbing is the new office norm: Gen Z and millennials are blame-shifting, snitching, and setting others up to fail—but so are managers
Successreturn to office
Backstabbing is the new office norm: Gen Z and millennials are blame-shifting, snitching, and setting others up to fail—but so are managers
By Orianna Rosa RoyleJuly 18, 2026
2 days ago
The Best Vitamins for Kids (2026): Support Their Immunity, Growth, and More
HealthDietary Supplements
The Best Vitamins for Kids (2026): Support Their Immunity, Growth, and More
By Emily PharesJuly 17, 2026
3 days ago

Most Popular

'Dr. Doom' Nouriel Roubini says we're headed for universal basic income or 'some form of socialism' as AI revolutionizes work—He calls that optimistic
AI
'Dr. Doom' Nouriel Roubini says we're headed for universal basic income or 'some form of socialism' as AI revolutionizes work—He calls that optimistic
By Jason MaJuly 18, 2026
2 days ago
Power companies are using eminent domain to seize land for data centers as 70% of Americans say not in my backyard
AI
Power companies are using eminent domain to seize land for data centers as 70% of Americans say not in my backyard
By Aaron Walayat and The ConversationJuly 19, 2026
1 day ago
Red Lobster’s 37-year-old CEO waited tables before joining the C-suite—he says it was a crash course in managing ‘difficult people and situations’
Success
Red Lobster’s 37-year-old CEO waited tables before joining the C-suite—he says it was a crash course in managing ‘difficult people and situations’
By Preston ForeJuly 19, 2026
1 day ago
Indeed chief economist: Aging Baby Boomers are America's real labor problem, not AI
Commentary
Indeed chief economist: Aging Baby Boomers are America's real labor problem, not AI
By Svenja GudellJuly 18, 2026
2 days ago
A decade after the ‘Godfather of AI’ said radiologists were obsolete, their salaries are up to $571K and demand is growing fast
AI
A decade after the ‘Godfather of AI’ said radiologists were obsolete, their salaries are up to $571K and demand is growing fast
By Marco Quiroz-GutierrezJuly 19, 2026
23 hours ago
'Right to repair' is coming to cars, but there's still this big blind spot as consumers demand more autonomy
Politics
'Right to repair' is coming to cars, but there's still this big blind spot as consumers demand more autonomy
By Joshua HongJuly 19, 2026
1 day ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.