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Human in the Loop: When to Trust the Machine

June 01, 2026 00:00 AM UTC
- Updated June 02, 2026 01:46 AM UTC

Agentic systems are now fully embedded with workflows, making decisions, flagging risks, and acting autonomously at scale. So the question keeping COOs up at night isn't whether to automate. It's something harder: when do you trust the machine, and when do you take back the wheel? This session will examine real examples of organizations navigating this balance with intention: where they've deployed agentic systems, what they've learned about when to trust the machine and when to pull back. Hear what works, what doesn't, and how to build operating models where human judgment and AI capability harmonize to unlock true competitive advantage. Sarah Franklin, Chief Executive Officer, Lattice Francine Katsoudas, EVP and Chief People, Policy and Purpose Officer, Cisco Moderator: Kristin Stoller, Editorial Director, Fortune; Co-Chair, Fortune COO Summit

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