6 Best NAD Supplements of 2025: Expert Reviewed and Tested

We worked with a certified nutrition coach to evaluate and select the top NAD+ supplements of 2025, providing a list of clinically backed and third-party tested options for beginners and advanced users of NAD+ alike.

Best NAD+ Supplements of 2025

• Best NAD+ Supplement Overall: Omre NMN+Resveratrol
• Best NAD+ Boosting Supplement: PartiQlar NR
• Best NAD+ Supplement for Women: Wonderfeel Youngr NMN
• Best Powder NAD+ Supplement: ProHealth NMN Pro Powder 1000
• Best NAD+ Supplement for Men: Nutricost NAD+
• Best NAD+ Supplement for Energy: Innerbody Labs NAD+ Support

Best NAD+ Supplements Comparison Table

Best NAD+ Supplement Overall: Omre NMN + Resveratrol

Omre NMN + Resveratrol

An NAD+ supplement that includes micronized resveratrol for cellular health

Fortune score

4.5/5

Check Price

at Omre

Key product features

• Our thoughts: We like the clinically backed dosages of key ingredients
• NMN per serving: 500 mg
• Serving size: 2 capsules
• Who it’s for: Those looking to take a single supplement that helps with energy, anti-aging, and improved cognition
• What makes it different: Includes BioPerine, a black pepper extract that may help with absorption

Pros and Cons

Pros

• Made in the USA
• Ingredient transparency on the product page
• Over 99% purity NMN

Cons

• Only available online, not in stores
• More expensive than other options on our list
• May cause mild digestive issues

Our Thoughts on Omre NMN + Resveratrol

Omre NMN + Resveratrol is our pick for the best overall NAD+ supplement because it has clinically backed dosages of both NMN and micronized trans-resveratrol, which work together to boost NAD+ production and improve cellular health. The supplement also includes the black pepper extract BioPerine, which may further help with absorption. All together, these components may potentially help improve energy and cognition while slowing the effects of aging. 

Our tester Pete put Omre NMN + Resveratrol to the test and immediately liked the product’s sleek packaging and gold label. He also found the instructions to be easy to follow, and gave the supplement a 5 out of 5 for both first impressions and ease of instructions. “Just take two capsules daily in the morning with food, or as recommended by your healthcare professional,” he explained. 

After scrutinizing the pills and taking his first dose, Pete deducted a few points for swallowability, giving the supplement a 3 out of 5 in this category. “It’s an average-size clear capsule with an off-white powder inside,” he said. “The capsule is about 1 inch in length and 1 cm in diameter. It has no taste.” That said, he awarded it a 5 for side effects and said he experienced no unwanted outcomes after consuming the capsules. 

Pete appreciated how transparent the website and label is on this product, and the 99% purity of the ingredients. “The supplement contains 500 mg of NMN powder, 500 mg of resveratrol, and 5 mg of Bioperine black pepper extract,” he said. “Both the NMN and resveratrol are designed to support healthy aging, and Bioperine is added to enhance the absorption of the resveratrol. The website says the product is third-party tested and they provide Certificates of Analysis on the site.”

Unfortunately that purity and transparency doesn’t come for cheap. The biggest area that Pete dinged the Omre NMN + Resveratrol is price, which is around $2 per serving. This is far from the most expensive NAD+ supplement we tested, but it isn’t the cheapest either, he noted. 

Best NAD+ Boosting Supplement: PartiQlar NR

PartiQlar NR

A NAD+ boosting supplement

Fortune score

4/5

Check Price

at PatiQlar

Key product features

• Our thoughts: These capsules may help boost natural NAD+ levels
• NR per serving: 500 mg
• Serving size: 1 capsule
• Who it’s for: Folks who want to boost their own NAD+ production
• What makes it different: PartiQlar’s product may also help improve energy levels

Pros and Cons

Pros

• Third-party tested with transparency around results
• Budget-friendly
• No artificial additives

Cons

• Doesn’t contain NAD+
• More research is needed

Our Thoughts on PartiQlar NR

Looking to boost your own body’s NAD production, rather than taking a supplement? That’s where PartiQlar’s NR comes in. This product packs 500 milligrams of nicotinamide riboside, a form of vitamin B3 that your body converts to NAD+. NR not only helps potentially increase your NAD+ levels, but it also may offer a lift in daily energy. However, more research is needed to build a true connection between NR supplements and increased NAD+ levels.

Upon first receiving the product, our tester Pete gave his first impression a 5 out of 5 rating. PartiQlar’s NR comes in a small, slim plastic container with an easy-to-open screw lid. The dark gray label and white text are easy to read. Plus, the bottle is easy enough to fit into a work bag or travel tote.

Pete also gave the swallowability a 5 out of 5. “This supplement comes in a small, clear capsule, which is only about three quarters of an inch in length and a half centimeter in diameter,” he describes. “The recommended serving size is only one capsule daily, which is manageable.”

The product had no taste or aftertaste that Pete noticed after swallowing the capsule, giving the brand a 5 out of 5 in this category, too.

“I had no digestive issues or negative side effects,” Pete said, giving the experience a 5 out of 5. “I didn’t experience any noticeable benefits from using this product, but I only took it for one day.” So, upon longer-term use, you may notice more benefit.

Overall, Pete thinks this product has a solid formula, though you do need to manage your expectations. “While the current research on both NR and NMN supplements is promising, these supplements are still relatively new and the actual benefits are still being studied,” he said. “That said, the 500 milligram dose included in this supplement is a strong dose and one that would be effective based on the current scientific literature at increasing NAD+ levels in the body.”

Best NAD+ Supplement for Women: Wonderfeel Youngr NMN

Wonderfeel Youngr NMN

A NAD+ supplement for anti-aging and cellular health

Fortune score

4/5

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at Wonderfeel

Key product features

• Our thoughts: A great value for a product that exceeds the clinical dosages
• NMN per serving: 900 mg
• Serving size: 2 capsules daily
• Who it’s for: Women looking for a clinically backed anti-aging supplement
• What makes it different: It was developed by a Harvard doctor with nearly 30 years of NAD+ research.

Pros and Cons

Pros

• Third-party tested
• Manufactured in cGMP-certified USA facilities
• Vegan, non-GMO, gluten-free

Cons

• May not be suitable for folks who are pregnant or nursing
• Only available online, not in stores
• Effects may not be immediate

Our Thoughts on Wonderfeel Youngr NMN

As with most other supplements, NAD and NMN supplements aren’t gender-specific—most formulas work for most folks. That said, we chose Wonderfeel Younger NMN as the best NAD+ supplement for women because it’s been specifically formulated with clinically backed dosages of NMN, resveratrol, ergothioneine, and more to improve cellular energy and slow the aging process. The supplement was engineered by a Harvard doctor with nearly 30 years of experience in NAD+ study and development. Not only is Wonderfeel transparent about its third-party testing, but the product is also vegan, gluten-free, and non-GMO—and it was manufactured in the USA in cGMP-certified facilities.

While this isn’t necessarily a gender-specific product, we found it to be a good option for women due to the metabolic effects and reduction in energy we tend to experience from perimenopause onward. This product has a powerful 900mg dose of NMN, plus other research-backed ingredients like resveratrol and antioxidants.

Our tester Gwen gave the product a 5 for first impressions. “The container is designed to look like a pill, which I think is cute,” she said. “I also like that it’s small enough to fit easily in my bag.” Gwen also thought the two-pills-a-day morning instructions to be easy enough to follow and gave the supplement another 5 in this category. 

Our tester Pete, a certified nutrition coach, also appreciated the formulation, which includes a high dosage of NMN and other ingredients. “The full two-capsule serving size contains 1,000 mg of NMN,” he said. Most studies on humans are using dosages between 250 and 500 mg per day so this is above that. That said, dosages up to 1,200 mg/day have been studied with no serious adverse effects reported.” After taking two capsules, he reported no noticeable side effects and gave the supplement another 5 for this. 

The only major area where Pete discounted this supplement is in the price category. Pete gave the Wonderfeel a 1 out of 5; however, this is in comparison to all the supplements we’ve tested across the board. At $1.73 per serving, Wonderfeel is actually priced pretty well compared to the other NAD+ supplements in our test roster, which range from 73 cents a serving to more than $3. We think it’s a good value for its dosage strength and formula. 

Best Powder NAD+ Supplement: ProHealth NMN Pro Powder

ProHealth NMN Pro Powder 1000

A NAD+ powder with clinically backed dosages of NMN

Fortune score

4/5

Check Price

at ProHealth

Key product features

• Our thoughts: This powder stands out for its efficacy and bioavailability
• NMN per serving: 1000 mg
• Serving size: 1 scoop
• Who it’s for: Men who want to drink their NAD+ for potentially quicker absorption
• What makes it different: ProHealth has a long-standing reputation for the purity and potency of its formulations

Pros and Cons

Pros

• Third-party tested with transparency around results
• ProHealth Longevity has been in business since 1988
• Cheaper than most capsule supplements, especially with subscribe and save

Cons

• Tester found it had a sweet aftertaste
• Takes more time to consume than capsules
• Pricey

Our Thoughts On ProHealth NMN Pro Powder

We chose ProHealth NMN Pro Powder 1000 as our best NAD+ powder supplement. We love the powder formula’s purity, third-party testing, and ease of use appeal to those who value transparency and simplicity. The powder format of this drink not only makes it a great option for those who are tired of swallowing pills, but also allegedly speeds up absorption and bioavailability. Overall, we felt it to be a quality daily choice for supporting metabolism, energy levels, endurance, and cognitive health.  

Our tester Kate described the powder’s container as having a “clean and classy” appearance. She gave the product a 5 for both first impressions and ease of instructions. “It says to take one to two scoops a day,” she said. “The directions are easy to find and are listed out on the back of the bottle.” 

Mixability can be an issue with powders, but it took Kate less than 60 seconds to shake ProHealth NMN’s powder into smooth perfection in a 10ml glass of water. “It dissolved really well!” she said. “There are no visible chunks or grittiness. It really just looks like water.” After further praising the consistency, she gave the powder a 5 out of 5 in this category.

However, the taste of the mixture only earned a 3 out of 5. “It is very, very sweet,” she said. “It has a strong pineapple and mango flavor to it, which isn’t my favorite. My other tester didn’t mind the sweetness so I really think this would be a personal preference for the taste.” Kate also noted the same sweet aftertaste after finishing the powder, though she experienced no other side effects or digestive issues. “I actually had a great amount of energy after taking it,” she said. 

Ultimately she reported an overall positive experience with the product. “I would recommend this for someone who is not looking for a budget-friendly NAD+ product,” she said. “But I loved the packaging and the quality of the product, so it does make sense for this price point.” 

Best NAD+ Supplement for Men: Nutricost NAD+

Nutricost NAD+

A single-ingredient NAD+ supplement

Fortune score

4/5

Check Price

at Nutricost

Key product features

• Our thoughts: We like this easy to swallow, high potency NAD+
• NAD per serving: 1,000 mg
• Serving size: 2 capsules
• Who it’s for: Folks looking for a straightforward, simple NAD+ formula
• What makes it different: Manufactured in an NSF Certified, GMP compliant, and FDA registered facility

Pros and Cons

Pros

• High potency per serving
• No artificial additives or fillers
• Vegan and gluten-free

Cons

• Difficult to find in stores
• No complementary ingredients for synergistic benefits
• More expensive than some other options on our list

Our Thoughts on Nutricost NAD+

Nutricost NAD+ is our pick for the best NAD+ supplement for men because it has a straightforward, minimalist formula and effective dosage of 1,000 milligrams per serving. Although there’s nothing gender-specific about its efficacy or health benefits, men may particularly appreciate this straightforward composition. It’s also vegan, gluten-free, and manufactured in an NSF Certified, GMP compliant, and FDA registered facility. Plus, each bottle contains 60 servings, so you can shop less frequently.

Pete tested Nutricost’s NAD+ supplement, rating it a 5 out of 5 for his first impression. “It’s a white plastic bottle with a blue screw top lid that opens and closes easily. The label has a matte finish that’s easy to read. The container is small enough to be travel friendly,” he said. The directions were simple and easy to follow, and Pete rated them a 5 out of 5 in this category. 

Unfortunately, he did have to rate the swallowability of Nutricost’s NAD+ as a 3 out of 5. The capsules are standard size, Pete said, about one inch in length and one centimeter in diameter and are clear with a white powder inside. The serving size is two capsules per day but they weren’t the most convenient to swallow. That said, Pete did find the capsules to be tasteless and odorless when testing them, which was a plus. 

After trying these NAD+ supplements a few times, he didn’t experience any side effects, rating it a 5 out of 5 in this category. Though, he didn’t necessarily feel immediate benefits either. 

Our team also loved the dosage this product provides. Nutricost’s NAD provides 1,000 milligrams of NAD per serving, which is large compared to other options. “This is a higher dosage than most NAD supplements on the market,” Pete said. “They’re typically between 250 and 500 milligrams per serving.”

Best NAD+ Supplement for Energy: Innerbody Labs NAD+ Support

Innerbody Labs NAD+ Support

A formula to enhance cellular energy and metabolism through both NMN and NR

Fortune score

4/5

Check Price

at Innerbody Labs

Key product features

• Our thoughts: We like that it contains added compounds (TMG, spermidine, and BioPerine) to optimize absorption of NAD+
• NAD per serving: 700 mg NMN
• Serving size: Three capsules
• Who it’s for: Folks feeling fatigued or mentally foggy
• What makes it different: Contains dual NAD+ precursors: 700mg of NMN and 400mg of NR

Pros and Cons

Pros

• Includes NMN and NR for enhanced NAD+
• Contains BioPerine for increased absorption
• Save up to 30% by buying multiple bottles at once

Cons

• More complex formula than other options on our list
• Expensive
• Not available in stores

Our Thoughts on Innerbody Labs NAD+ Support

Innerbody Labs NAD+ Support is our pick for the best NAD+ Supplement for Energy because it helps target cellular metabolism from multiple angles. By combining NMN (700 milligrams) and NR (400 milligrams), it fuels the body’s NAD+ pathways that power cellular energy. Research shows that boosting NAD+ helps activate sirtuins and improve mitochondrial function, essential for both energy and endurance.

Gwen tested Innerbody’s NAD+ Support, rating it a 5 out of 5 for her first impression. “The container for this product is incredibly sleek and simple,” she said. “I love the clean white background and the pops of red. I also like that it’s not overly cluttered with information on the front.” Gwen also noted that the supplement facts are clear and easy to understand, rating it a 5 out of 5 for ease of understanding and following the directions.

She rated the swallowability a 3 out of 5: “The capsule is a standard size, I wouldn’t say that it’s too large or difficult to swallow,” Gwen said. “The serving size is three capsules, though. This isn’t problematic for me because I’m used to taking a bunch of supplements, but some folks may need to take the pills individually,” she said. If you prefer fewer pills per serving, we recommend you go with Nutricost NAD.

Gwen didn’t notice any taste with this product. “It doesn’t taste chalky or have any kind of aftertaste that I noticed,” she said, rating it a 5 out of 5 for taste. She didn’t experience any side effects or digestive upset, either.

What are NAD+ Supplements?

Nicotinamide adenine dinucleotide (NAD+) is a vital coenzyme present in every living cell, essential for converting nutrients into usable energy (ATP) and maintaining proper cellular function. It plays critical roles in DNA repair, gene expression, metabolism, and cell signaling, all of which are central to energy production and longevity. However, NAD+ levels naturally decline with age, oxidative stress, and unhealthy lifestyle factors, leading to decreased metabolic and cognitive function and faster cellular aging. 

NAD+ supplements are formulated to help replenish these declining levels. Most products do not contain NAD+ itself but precursor molecules (like nicotinamide riboside [NR], nicotinamide mononucleotide [NMN], or niacin) that are converted into NAD+ within the body. This process boosts cellular NAD+ and enhances mitochondrial energy production. By restoring NAD+ balance, these supplements may support sustained energy, improved focus, and more efficient cellular repair mechanisms.

What do NAD+ Supplements Do in the Body?

NAD+ supplements work at the cellular level of your body to restore energy, repair tissues, and improve metabolic resilience. While not a cure-all, maintaining healthy NAD+ levels may contribute to greater vitality and longevity through reduced oxidative stress.

How We Tested and Selected the Best NAD+ Supplements

We tested and evaluated NAD+ supplements and scored them on a scale of 1-5 for factors such as first impressions, easy-to-follow directions, swallowability, side effects, and value. Our testers evaluate the products based on their own individual experiences and preferences. We then review their testing feedback and data to share our findings and recommendations with you.

Formula

When selecting and testing NAD+ supplements, we worked with a certified nutrition coach to ensure each formula meets the highest standards for efficacy and safety. The evaluation process focuses on clinically supported dosages that reflect current research, seeking NAD+ products that deliver the optimal amounts shown in peer-reviewed studies. Ingredient quality and transparency are top priorities, and we favored NAD+ supplements made in GMP-certified facilities, with third-party testing, and free of unnecessary additives.

Taste and Texture

Flavor is a big part of our testing process. We asked our testers to provide feedback on the taste, aftertaste, and swallowability of the NAD+ supplements.

Form

Serving sizes for NAD+ supplements range from a single capsule to multiple pills. Whenever possible, we chose NAD+ products that required fewer capsules per serving for added convenience. We also tested NAD+ supplements in various forms, such as a mixable powder and face cream, for folks who like to vary the way they ingest the supplement.

Third-Party Testing

We selected NAD+ supplements that have been verified through third-party testing for safety, purity, and label accuracy. This process also screens for harmful substances like heavy metals and pesticides.

For athletes, third-party testing is crucial to confirm there are no banned substances—products should be sport certified. Since the FDA does not regulate supplements, independent verification is essential for safety, accuracy, and consumer trust.

Value

When considering value, we place a higher value on brands that source their ingredients in America and have certifications, such as Informed Choice.

How to Find the Best NAD+ Supplement for You

NAD+ supplement needs vary based on your age, lifestyle, and any specific health goals you may have related to energy or cellular support.

Consider these factors when choosing the most suitable NAD+ supplement for you.

Your Body’s Needs

NAD+ supplements can play a helpful role in supporting energy metabolism and cellular repair, but they aren’t essential for everyone. Think of them as an optional boost to complement healthy habits—like proper nutrition, exercise, and good sleep—rather than a necessary cornerstone of wellness.

Formula

Everyone has different dietary needs, so it’s worth checking the ingredient list before purchasing. Some NAD+ formulas include added vitamins, collagen, or supportive compounds, which might align differently with various diet types or fitness goals. If a supplement includes additional nutrients, compare them with your recommended daily values (RDVs) to avoid excess intake. Choosing a formula that complements your existing nutrition can help you make the most of your NAD+ supplement.

Cost

NAD+ supplements are typically taken daily, and can be pricey, so consider your budget before purchasing. Cleaner formulations, meaning those without artificial sweeteners or additives, may cost more because of their higher quality and ingredient sourcing.

Third-Party Testing

Because the FDA does not regulate supplements, third-party testing provides independent verification of a NAD+ supplement’s safety, purity, and label accuracy. This process protects against risks like mislabeling, contamination, or banned substances, giving you confidence in the products you choose. Independent testing is crucial for ensuring both product quality and safety.

Benefits of NAD+ Supplements

Much like a NMN supplement or collagen powder, NAD+ supplements can offer an array of health benefits, potentially helping your longevity and metabolic health. Here are a few:

• Enhanced energy production: NAD+ helps to combat fatigue and improve endurance at the cellular level by converting nutrients into usable energy
• Improved cognitive and cellular health: NAD+ supports brain health by protecting neurons from oxidative stress and inflammation, promoting better memory, mental clarity, and overall cognitive function
• Metabolic and anti-aging support: Maintaining optimal NAD+ levels has been linked to better metabolic regulation, improved insulin sensitivity, reduced inflammation, and protection against age-related decline

How to Take NAD+ Supplements

Most NAD+ supplements come in capsule, tablet, powder, or even liquid form; they are typically taken daily. For best results: 

• Take NAD+ supplements in the morning, preferably with or after breakfast for optimal absorption and energy support throughout the day
• Start with the lowest recommended dose and increase gradually
• Consistency is key; regular daily use maintains steady NAD+ levels
• NAD+ supplements can be paired with ingredients like resveratrol or TMG for synergistic support, but we recommend talking with your doctor regarding combinations and medication interactions before starting or combining supplements

How Much NAD Should You Take Daily?

Clinical research indicates that the most effective daily dosage for NAD+ precursors (such as nicotinamide riboside or nicotinamide mononucleotide) typically falls within the range of 250 milligrams to 500 milligrams per day for most adults, though some studies safely use up to 1,000mg per day for more robust increases in NAD+ levels.

Are There Any Risks of Taking NAD+ Supplements?

NAD+ supplements are generally considered safe and well-tolerated for most people, with minor side effects such as nausea, headache, mild digestive upset, flushing, or fatigue possible. There are some risks: long-term safety of taking an NAD+ supplement is still being studied, especially for high doses or prolonged periods of use. NAD+ supplements may interact with medications or other health conditions, so we recommend speaking with your doctor before starting an NAD+ product.

Frequently Asked Questions