• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
InvestingCentene

Centene stock uncertainty as ACA subsidy expiration looms: What investors need to know about rising medical costs and 2026 Marketplace risk

Ashley Lutz
By
Ashley Lutz
Ashley Lutz
Executive Director, Editorial Growth
Down Arrow Button Icon
Ashley Lutz
By
Ashley Lutz
Ashley Lutz
Executive Director, Editorial Growth
Down Arrow Button Icon
September 12, 2025, 12:26 PM ET
Sarah London, chief executive officer of Centene Corp.
Sarah London, chief executive officer of Centene Corp.Michael Nagle/Bloomberg via Getty Images

Centene‘s stock has experienced a significant decline—more than 42% in the past six months—primarily due to the withdrawal of its 2025 financial guidance following some troubling developments in its core health insurance business.

Recommended Video

Centene’s recent stock drop is closely linked to a combination of higher-than-expected medical costs amid challenging trends in the Affordable Care Act (ACA) market and anticipation of the scheduled end to enhanced ACA subsidies at the end of 2025. While shares jumped earlier this week after Centene affirmed its guidance, which was higher than analysts’ estimates, it faces an uncertain road ahead.

Centene’s stock drop and ACA subsidies

  • Stock performance: Centene’s shares fell sharply in early July, reaching their lowest levels in nearly a decade. This plunge was triggered by worse-than-expected financial results, withdrawals of 2025 earnings guidance, and recognition of higher-than-expected medical costs as well as rising morbidity in its ACA and Medicaid populations.
  • ACA subsidies set to end: The enhanced ACA premium subsidies passed under the American Rescue Plan (ARP) and extended under the Inflation Reduction Act (IRA) are scheduled to sunset on Dec. 31. Without congressional action, this will result in significantly reduced subsidies or their outright elimination for many Marketplace members.
  • Investor implications: The looming expiration of subsidies is projected to shrink the pool of healthier, subsidized Marketplace enrollees. This would create an adverse selection problem—leaving a riskier, potentially sicker population in the insured pool—which could further drive up medical costs for ACA plans and erode Centene’s margins.

Centene’s business outlook

  • Short-term: The company faces major headwinds as it grapples with higher costs, deteriorating risk pools, and policy uncertainty about ACA subsidies for 2026 and beyond. Its Q2 2025 loss was its first in over a decade, leading to guidance withdrawals and widespread analyst downgrades. Efforts to reprice 2026 plans are underway to account for this new, tougher landscape.
  • Medium- to long-term: The outlook hinges on whether Congress acts to extend ARP/IRA subsidies. If not, Centene faces further pressure in its ACA business, with potential for increased uninsured rates and higher per-member costs as healthier enrollees exit the market.

Trends in healthcare costs

  • Medical cost inflation: U.S. healthcare cost growth is expected to remain elevated in 2025, with employer-sponsored plans near 8.5% and group market rates close to 7.5%.
  • Drivers: The expiry of enhanced ACA subsidies could push more people to go uninsured, resulting in a sicker insured population and higher claims costs. Ongoing challenges such as rising chronic disease prevalence, drug costs (including new price reforms), and healthcare workforce shortages will continue to put pressure on prices.
  • Mitigating factors: Enactment of new drug price controls and pent-up demand from the pandemic leveling off may help moderate some inflation, but most projections see healthcare costs outpacing GDP growth through this decade.

Investor takeaway: Centene stock faces a challenging outlook driven by ACA pressures, higher healthcare costs, and the policy risk posed by the scheduled end of enhanced federal subsidies after 2025.

For this story, Fortune used generative AI to help with an initial draft. An editor verified the accuracy of the information before publishing.

The Fortune 500 Innovation Forum will convene Fortune 500 executives, U.S. policy officials, top founders, and thought leaders to help define what’s next for the American economy, Nov. 16-17 in Detroit. Apply here.
About the Author
Ashley Lutz
By Ashley LutzExecutive Director, Editorial Growth

Ashley Lutz is an executive editor at Fortune, overseeing the Success, Well, syndication, and social teams. She was previously an editorial leader at Bankrate, The Points Guy, and Business Insider, and a reporter at Bloomberg News. Ashley is a graduate of Ohio University's Scripps School of Journalism.

See full bioRight Arrow Button Icon

Latest in Investing

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Fortune Secondary Logo
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • Future 50
  • World’s Most Admired Companies
  • See All Rankings
Sections
  • Finance
  • Fortune Crypto
  • Features
  • Leadership
  • Health
  • Commentary
  • Success
  • Retail
  • Mpw
  • Tech
  • Lifestyle
  • CEO Initiative
  • Asia
  • Politics
  • Conferences
  • Europe
  • Newsletters
  • Personal Finance
  • Environment
  • Magazine
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
  • Group Subscriptions
About Us
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Latest in Investing

The one metric Warren Buffett says can crash the stock market just hit a dizzying new high
InvestingFinance
The one metric Warren Buffett says can crash the stock market just hit a dizzying new high
By Shawn TullyApril 19, 2026
18 hours ago
benioff
CommentarySalesforce
AI’s next act: how Salesforce is turning efficiency gains into revenue
By Keith Ferrazzi and Wendy SmithApril 18, 2026
2 days ago
broker
EnergyMarkets
Oil is back to early war days, S&P 500 jumps to all-time high
By Stan Choe and The Associated PressApril 17, 2026
2 days ago
Current price of Ethereum for April 17, 2026
Personal FinanceEthereum
Current price of Ethereum for April 17, 2026
By Joseph HostetlerApril 17, 2026
3 days ago
Current price of Bitcoin for April 17, 2026
Personal FinanceCryptocurrency
Current price of Bitcoin for April 17, 2026
By Joseph HostetlerApril 17, 2026
3 days ago
broker
CommentarySoftware
The 3 forces quietly dismantling the business model that made enterprise software fabulously profitable
By Michael Jacobides and Stefano PuntoniApril 17, 2026
3 days ago

Most Popular

'We should absolutely be concerned about non-college-educated men today': higher rents, living at home, falling out of the labor market
Economy
'We should absolutely be concerned about non-college-educated men today': higher rents, living at home, falling out of the labor market
By Catherina GioinoApril 18, 2026
2 days ago
Thousands of CEOs admit AI had no impact on employment or productivity—and it has economists resurrecting a paradox from 40 years ago
AI
Thousands of CEOs admit AI had no impact on employment or productivity—and it has economists resurrecting a paradox from 40 years ago
By Sasha RogelbergApril 19, 2026
11 hours ago
The record-setting U.S. drought is so bad that 97% of the Southeast and two-thirds of the West are parched
North America
The record-setting U.S. drought is so bad that 97% of the Southeast and two-thirds of the West are parched
By Seth Borenstein and The Associated PressApril 18, 2026
1 day ago
The $6 billion Vatican Bank was beset by scandals, disastrous investments—and ties to the Mafia. How Pope Francis tried to fix it
Banking
The $6 billion Vatican Bank was beset by scandals, disastrous investments—and ties to the Mafia. How Pope Francis tried to fix it
By Marco Quiroz-GutierrezApril 18, 2026
1 day ago
Elon Musk bans résumés and cover letters in hiring for his chip team. These are the 3 bullet points he’s looking for instead
Future of Work
Elon Musk bans résumés and cover letters in hiring for his chip team. These are the 3 bullet points he’s looking for instead
By Jake AngeloApril 19, 2026
11 hours ago
Putin finally admits Russia's economy is in trouble and grasps for answers, after warnings about a financial crisis have been piling up
Economy
Putin finally admits Russia's economy is in trouble and grasps for answers, after warnings about a financial crisis have been piling up
By Jason MaApril 18, 2026
1 day ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.