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VC Alexa von Tobel launches new podcast ‘Inspired,’ looking to reset American ambition

Allie Garfinkle
By
Allie Garfinkle
Allie Garfinkle
Term Sheet Editor
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Allie Garfinkle
By
Allie Garfinkle
Allie Garfinkle
Term Sheet Editor
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July 14, 2025, 4:09 PM ET
Alexa von Tobel, Inspired Capital cofounder.
Alexa von Tobel, Inspired Capital cofounder.Inspired
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The Latin root of the word “ambition” literally means “to go around,” hinting that ambition isn’t just about drive—it’s the unrelenting ability to face a roadblock and, come hell or high water, find a way around it.

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In ancient Rome, ambition had political roots—those who were truly ambitious would “go around” canvassing for votes. Historically, ambition hasn’t always been seen as a virtue (just ask Macbeth). But in the United States, ambition became a defining ideal, championed by Founding Fathers like John Adams, who wrote about it as a virtue essential to Americans.

Alexa von Tobel, Inspired Capital cofounder and LearnVest founder, argues that this American ambition has corroded in recent years—and that it’s time for a reset, one that revives ambition to its most sweeping, optimistic form. This is especially true for VCs and entrepreneurs, she exclusively tells Fortune. 

“During a period of capital being effectively free, it became very easy to start companies,” said von Tobel, referencing ZIRP (zero interest rate policy) induced booms. “We were creating a lot of direct-to-consumer this and that, and building out incremental ideas—because capital effectively was everywhere. And in some ways, it was great: Entrepreneurship became mainstream. But as entrepreneurship became mainstream and capital was easy to access, we just started seeing a lot of incremental ideas. Coming out of COVID, some of that’s beginning to reset.”

Von Tobel has been thinking about this as an investor, backing companies like ShopMy, Solace, and Teamshares. (In 2024, Inspired raised $330 million for its third fund.) A long-time podcast host, she’s also been considering the state of entrepreneurial ambition from a narrative perspective: From 2019 to 2024, von Tobel hosted The Founders Project podcast for about 250 episodes via Inc. Now, she’s re-launched the podcast on her own as Inspired—taking its name from her firm and her ethos. 

The bi-weekly episodes are generally about an hour long and feature von Tobel interviewing entrepreneurs about taking truly ambitious swings and what it takes to make a vision reality. 

“I worry about the world,” von Tobel told Fortune. “As somebody who deeply cares about making the world a better place, I believe we have more problems than we’ve ever seen. And when I really dug deep on what I hope we see more of in the world it’s—no pun intended—inspiring people to dream bigger, think bigger.”

Von Tobel’s first guest on the new podcast, which launched last week, is Ben Lamm, founder and CEO of Colossal Biosciences, famous for its de-extinction efforts. This year, those efforts transcended science fiction, as Colossal revealed it had successfully genetically engineered the long-extinct dire wolf. Astro Teller, Captain of Moonshots at Google X, and Dr. Becky Kennedy, founder and CEO of Good Inside, are also scheduled as guests. 

“If someone says to me, ‘I want to be a lawyer’ I want them to say, ‘I want to be a Supreme Court justice,’” said von Tobel. “It’s truly just pushing yourself to say: Is this the point 0.01% of how big we can go to solve a problem and make the world better? Is this idea capable of improving four billion lives? Now, we’re at the scale we should be thinking about.”

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Allie Garfinkle
By Allie GarfinkleTerm Sheet Editor
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Allie Garfinkle is a senior writer and editor at Fortune, where she runs Term Sheet; leads coverage of private capital, investors, and startups; and co-chairs the Brainstorm conference series.

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