• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
Health

A New Suitor Has Reportedly Replaced J&J in This Over $20 Billion Biotech Deal

By
Reuters
Reuters
Down Arrow Button Icon
By
Reuters
Reuters
Down Arrow Button Icon
December 14, 2016, 7:32 AM ET
A logo is seen in front of the entrance at the headquarters of French drugmaker Sanofi in Paris
A logo is seen in front of the entrance at the headquarters French drugmaker Sanofi in Paris October 30, 2014. REUTERS/Christian Hartmann/File PhotoPhotograph by Christian Hartmann—Reuters

Switzerland’s Actelion is in talks with French drugmaker Sanofi about a deal, sources said on Wednesday, after U.S. healthcare group Johnson & Johnson abandoned efforts to buy the company.

Actelion’s (ALIOF) shares traded 10% lower amid concern among investors that J&J’s exit made a successful deal for Europe’s biggest biotech group less likely.

Sanofi (SNYNF) declined to comment.

The French drugmaker was trumped in August by Pfizer’s $14 billion bid for U.S. cancer drug company Medivation and is still eager for deals to broaden its drug line-up.

However, analysts said Sanofi CEO Olivier Brandicourt could ill afford to fail in a second high-profile bid.

Actelion told J&J (JNJ) it was confident it could attract an offer significantly higher than the approximately 250 Swiss francs per share the U.S. company had offered, according to one person familiar with the matter.

There were also disagreements about the proposed deal’s structure, the person added.

Actelion shares had closed at 208.50 Swiss francs on Tuesday, a 25% premium to their price before J&J’s bid became public two weeks and giving the company a market capitalization of 22.5 billion Swiss francs ($22.2 billion).

“I presume these parties are prepared to make offers that are more attractive than that which J&J was envisaging,” said Eleanor Taylor Jolidon, a fund manager at Union Bancaire Privee in Geneva, which is among Actelion’s top 40 investors.

“Otherwise, the board of directors would not have acted in the interests of the stakeholders by creating a situation in which J&J walked away.”

 

CEO’s Pivotal Role

The Swiss company, founded by its chief executive Jean-Paul Clozel in 1997, confirmed talks over a “possible strategic transaction” but did not name the counterparty.

A spokesman declined further comment but sources with knowledge of the matter identified Sanofi.

Analysts have previously named Sanofi as a potential buyer for Actelion, whose portfolio of drugs against deadly pulmonary arterial hypertension—elevated pressure in arteries connecting the heart and lungs—would supplement Sanofi’s Genzyme rare disease unit.

Even so, a competitive auction could drive up its price to unrealistic levels.

“Winning a bidding war when it comes to acquiring biopharmaceutical companies almost always equates to way over-paying,” wrote Tim Anderson, an Bernstein analyst.

“These are not bragging rights,” he said. “If Actelion were to go out at around $30 billion, this equates to around 13 times sales and 30 times earnings before interest and taxes. These are high figures.”

A source close to J&J said the main problem was Clozel did not want to sell. “It wasn’t about price, he simply doesn’t want to give up control,” the source said.

Clozel and his wife, Chief Scientific Officer Martine Clozel, have built up a world-leading drug portfolio at Actelion to treat pulmonary arterial hypertension.

They aim to expand in drugs for multiple sclerosis and clostridium difficile, but regulatory approvals for those are years away.

The company is also counting on its new pulmonary arterial hypertension treatments Opsumit and Uptravi, which combined are forecast to bring in nearly 4.5 billion francs in annual sales by 2020.

Clozel has rebuffed past pressure from some shareholders to do a deal, maintaining Actelion is better off staying independent. Five years ago, he successfully fended off an effort by activist hedge fund Elliott Management to put Actelion up for sale.

About the Author
By Reuters
See full bioRight Arrow Button Icon

Latest in Health

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • Future 50
  • World’s Most Admired Companies
  • See All Rankings
Sections
  • Finance
  • Leadership
  • Success
  • Tech
  • Asia
  • Europe
  • Environment
  • Fortune Crypto
  • Health
  • Retail
  • Lifestyle
  • Politics
  • Newsletters
  • Magazine
  • Features
  • Commentary
  • Mpw
  • CEO Initiative
  • Conferences
  • Personal Finance
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
About Us
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Most Popular

placeholder alt text
Economy
Elon Musk warns the U.S. is '1,000% going to go bankrupt' unless AI and robotics save the economy from crushing debt
By Jason MaFebruary 7, 2026
1 day ago
placeholder alt text
Success
Even with $850 billion to his name, Elon Musk admits ‘money can’t buy happiness.’ But billionaire Mark Cuban says it’s not so simple
By Preston ForeFebruary 6, 2026
2 days ago
placeholder alt text
Success
Gen Z Patriots quarterback Drake Maye still drives a 2015 pickup truck even after it broke down on the highway—despite his $37 million contract
By Sasha RogelbergFebruary 7, 2026
1 day ago
placeholder alt text
AI
AI can make anyone rich: Mark Cuban says it could turn 'just one dude in a basement' into a trillionaire
By Sydney LakeFebruary 7, 2026
1 day ago
placeholder alt text
Future of Work
Anthropic cofounder says studying the humanities will be 'more important than ever' and reveals what the AI company looks for when hiring
By Jason MaFebruary 7, 2026
1 day ago
placeholder alt text
Energy
Next-gen nuclear's tipping point: Meta and hyperscalers start deals with Bill Gates’ TerraPower, Sam Altman-backed Oklo, and more
By Jordan BlumFebruary 7, 2026
22 hours ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.


Latest in Health

Joanna Griffiths, the founder and president of Knix
SuccessEntrepreneurs
The founder of $400 million company Knix sees a hypnotherapist to ‘rewire’ her brain and work through her fear of failure
By Emma BurleighFebruary 8, 2026
6 hours ago
trump
PoliticsElections
As Republicans slash $1 trillion out of Medicaid, Democrats see ‘a banger of an issue’ to campaign on
By Ali Swenson, Jeff Amy and The Associated PressFebruary 7, 2026
1 day ago
Eileen GU, wearing a red and while Beijing Olympics coat, smiles with her skis.
SuccessSports
Freestyle skier Eileen Gu says she suffered ‘post-Olympic depression’: ‘You can win the Olympics and still just enter the deepest rut of your life’
By Sasha RogelbergFebruary 7, 2026
1 day ago
North Americademographics
U.S. births dropped last year, offsetting 2024’s increase and dashing hopes for an upward trend
By Mike Stobbe and The Associated PressFebruary 6, 2026
2 days ago
Birch mattress
Healthmattresses
Birch Mattress Review 2026: Tested by Experts
By Christina SnyderFebruary 6, 2026
2 days ago
A woman holds up a peace sign as she runs in the New York City Marathon.
RetailLuxury
Gen Z’s latest status symbol is running a marathon—and it’s terrible news for Gucci, Louis Vuitton, and Hermès
By Sasha RogelbergFebruary 6, 2026
2 days ago