Hollywood lost an icon Tuesday evening with the death of Garry Marshall. The influential filmmaker died from complications of pneumonia following a stroke at a hospital in Burbank, California. He was 81 years old.

Marshall’s list of credits spans across decades and includes such accomplishments as creating Happy Days, transforming The Odd Couple from a Broadway play to a five-season TV show, and helmingPretty Woman and The Princess Diaries.

The New York native touched many lives in and outside of Hollywood.

“Thank you for my professional life,” wrote Happy Days alum Henry Winkler on Twitter. “Thank you for your loyalty, friendship and generosity.”

Here’s a sampling of reactions from those mourning Marshall’s death:

GARRY MARSHALL Rest In Peace .. Thank you for my professional life. Thank you for your loyalty , friendship and generosity .

— Henry Winkler (@hwinkler4real) July 20, 2016

Larger than life, funnier than most , wise and the definition of friend https://t.co/k8qxEe4rIZ

— Henry Winkler (@hwinkler4real) July 20, 2016

Oh, man. RIP Garry Marshall. Sad. Just talked to him. Great guy.

— marc maron (@marcmaron) July 20, 2016

RIP #GarryMarshall will miss that talented one

— octavia spencer (@octaviaspencer) July 20, 2016

R.I.P. Garry Marshall. A great, great guy and the best casino boss in the history of film. #lostinamerica

— Albert Brooks (@AlbertBrooks) July 20, 2016

Thank you Gary Marshall for all the joy and laughter. You are missed already and forever https://t.co/XyoPKvrGwf

— Richard Schiff (@Richard_Schiff) July 20, 2016

Worked with Garry Marshall on the new Odd Couple. I was so excited to meet him. He was gracious,kind & very funny. #GarryMarshal #legend

— Dave Foley (@DaveSFoley) July 20, 2016

https://twitter.com/TopherGrace/status/755605926099292160?ref_src=twsrc%5Etfw

https://twitter.com/zeldawilliams/status/755602022049599488?ref_src=twsrc%5Etfw

My heart is broken. Comic genius, Garry Marshall has died. A cultural icon who was brilliant till the end. Always kind. Always funny! RIP

— Wendell Pierce (@WendellPierce) July 20, 2016

A comedy genius has passed on… #RIP #GarryMarshall … I sat & watched everything you created one day hoping it could be me on that screen

— Sherri Shepherd (@sherrieshepherd) July 20, 2016

I lost a friend & mentor. We lost a beautiful man & masterful story teller. Gary Marshall I love you. I hope I get to go where you are.

— ashton kutcher (@aplusk) July 20, 2016

I will never be the same. I can't even put into words what #GarryMarshall has meant to my life. I am just heartbroken. #RIP kind Sir.

— yvette nicole brown (@YNB) July 20, 2016

What the world has lost! He was such a dear man. I was so excited about getting to see him again soon. I am inconsolable. #GarryMarshall

— yvette nicole brown (@YNB) July 20, 2016

Garry Marshall would always say (and lived by this) "It's nice to be important, it's more important to be nice." RIP Legend

— donal logue (@donallogue) July 20, 2016

RIP #GarryMarshall . Talk about a bright light! You will be missed.

— Tony Goldwyn (@tonygoldwyn) July 20, 2016

Very sorry to hear of loss of Garry Marshall. Those who grew up when I did remember a TV schedule filled with his humor and inspiration.

— Jane Espenson (@JaneEspenson) July 20, 2016

Garry Marshall, ‘Pretty Woman’ Director and Creator of ‘Happy Days,’ Dies at 81 https://t.co/1qW97r3hXd via @variety Always loved Garry! RIP

— Morgan Fairchild (@morgfair) July 20, 2016

RIP Garry Marshall. The scene between he and @AlbertBrooks in Lost in America is pure comedic genius. Please enjoy https://t.co/k5Y9vSDh7P

— Matt Oswalt (@MattOswaltVA) July 20, 2016

https://twitter.com/HeatherMatarazz/status/755603375526322177?ref_src=twsrc%5Etfw

Our beloved Garry Marshall has passed. Our family will miss him so very much. RIP dear one. pic.twitter.com/F7y3RkLn1Z

— Goldie Hawn (@goldiehawn) July 20, 2016

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