To replace Styrofoam and similar landfill-clogging blights, this New York company relies on mushrooms, using mycelium roots from fungi to make biodegradable packaging for Dell and Steelcase (SCS).

Narayana Health

The Indian hospital franchise has a policy of turning no one away for lack of funds. It offers cardiac surgeries at 2% of the cost in the U.S., along with similarly low-cost cancer care and marrow transplants.

Natura

This Brazilian cosmetics company sources materials sustainably from the Amazon region. With $2.1 billion in sales in 2014, it’s the biggest company to earn “B Corp.” certification for its conscious capitalism from nonprofit B Labs.

To see the full Change the World list, visit fortune.com/change-the-world.

A version of this article appears in the September 1, 2015 issue of Fortune.