Good morning and happy Friday.


Here’s an extra-credit question for those in the mood for a brainteaser this early in the day: Name the industry that is the most intensely regulated by government, the most overwhelmed by haphazard data, the most guild-protected, and the least transparent to consumers when it comes to the questions of what things truly cost, why they cost so much, and who’s paying for them.


Want a hint? The sector accounts for more than 17% of U.S. GDP—and spending on these goods and services is expected to grow at a staggering 5.8% a year over the next decade—1.3 percentage points faster than the economy as a whole.


Yup, you got it: We’re talking about health care.


If ever there were an industry ripe for disruption, this one is it. The good news is, there’s reason to think a seismic shift may actually be coming. As big data (and, importantly, smarter data) converge with biology, and a host of new technologies—from sophisticated wearable sensors to virtual reality to 3D printing to gene-editing tools to artificial intelligence—begin to mature, we are seeing the rumblings of a revolution of sorts.


Can it be that Moore’s Law is finally asserting its authority over health care? Will prices really come down? Hmmm. That may be too much to ask for in the near term. But it may finally be possible to get more for our money.


That, indeed, is what Fortune is going to explore over the first two days of November in an extraordinary gathering in San Diego. With help from our founding sponsor, IBM Watson Health, we are convening some of the best and brightest minds in health, medicine, technology, and pitch-fork disruption at our inaugural Fortune Brainstorm HEALTH conference. We’ll probe the potential of all this new medtech, challenge orthodoxy, poke a few sacred cows, and do a fair amount of big-sky dreaming about what’s possible—and what ought to be.


Here’s a sneak peek at the working agenda and speakers. (I’m not sure if I’m supposed to share this yet, but heck, I’m the co-chair.) Our goal isn’t just to talk for a couple of days, though. Our intention, rather, is to build a powerful new community of leaders at the forefront of this 21st century healthcare transformation.


The conference is by invitation only, but if you’ve got some expertise or professional interest in this area, we welcome your application as a delegate. CEO Daily readers, naturally, get special consideration.


More news below.


Clifton Leaf

Alan Murray is on vacation this week. Fortune’s Deputy Editor Clifton Leaf is filling in.

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