• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia

Trendingnow

1

Social Security unraveling: 7,100 workers sacked, performance metrics retired, disability claims falling

2

Erin Brockovich, the activist who defeated a utility giant and inspired a Julia Roberts film, is pushing data centers to be more transparent

3

'Where we are today is frightening': a Pulitzer-winning historian sees a doomsday scenario involving China and the national debt

1

Social Security unraveling: 7,100 workers sacked, performance metrics retired, disability claims falling

2

Erin Brockovich, the activist who defeated a utility giant and inspired a Julia Roberts film, is pushing data centers to be more transparent

3

'Where we are today is frightening': a Pulitzer-winning historian sees a doomsday scenario involving China and the national debt
HealthParkinson's

Parkinson’s patients show improvement after taking cancer drug

Claire Zillman
By
Claire Zillman
Claire Zillman
Editor, Leadership
Down Arrow Button Icon
Claire Zillman
By
Claire Zillman
Claire Zillman
Editor, Leadership
Down Arrow Button Icon
October 19, 2015, 5:00 PM ET
Courtesy of Novartis

Researchers at Georgetown University Medical Center on Saturday revealed what could be a major breakthrough in the treatment of Parkinson’s disease.

A study unveiled at the Society for Neuroscience’s annual meeting found that 11 patients with Parkinson’s disease with dementia who were given nilotinib, an FDA-approved drug for leukemia that’s sold by Novartis as Tasigna, experienced improved cognition, motor skills and non-motor function in a 12-patient, six-month trial.

Fernando Pagan, a GUMC associate professor of neurology who directs the Movement Disorders Program at MedStar Georgetown University Hospital, said that to his knowledge, the study “represents the first time a therapy appears to reverse—to a greater or lesser degree depending on stage of disease—cognitive and motor decline in patients with these neurodegenerative disorders.”

In some patients, the results of the treatment were rather dramatic. A release from GUMC says that one patient who was confined to a wheelchair was able to walk again and that three other patients who could not speak were able to hold conversations.

One patient in the trial, Alan Hoffman, a professor emeritus of social science education at Georgia State University, was diagnosed with Parkinson’s disease in 1997. Before taking nilotinib, he said he didn’t do much around the house. “Now,” he told GUMC, “I empty the garbage, unload the dishwasher, load the washer and the dryer, set the table, even take responsibility for grilling.”

Pagan said that a larger, more comprehensive study must be done before determining the drug’s true impact, but if the drug’s effectiveness is confirmed in such tests, nilotinib could become the first treatment to impede the killing of brain cells that’s consistent with Parkinson’s, according to NPR. GUMC says its researchers are now planning larger clinical trials with nilotinib for patients with Parkinson’s and other similar diseases including Alzheimer’s disease, likely to begin in 2016.

About the Author
Claire Zillman
By Claire ZillmanEditor, Leadership
LinkedIn iconTwitter icon

Claire Zillman is a senior editor at Fortune, overseeing leadership stories. 

See full bioRight Arrow Button Icon

Latest in Health

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Fortune Secondary Logo
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • World's Most Admired Companies
  • See All Rankings
  • Lists Calendar
Sections
  • Finance
  • Fortune Crypto
  • Features
  • Leadership
  • Health
  • Commentary
  • Success
  • Retail
  • Mpw
  • Tech
  • Lifestyle
  • CEO Initiative
  • Asia
  • Politics
  • Conferences
  • Europe
  • Newsletters
  • Personal Finance
  • Environment
  • Magazine
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
  • Group Subscriptions
About Us
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Latest in Health

pox
North AmericaScience
Two government virologists smuggled Mpox vials into the U.S. It’s not clear why
By Ed White and The Associated PressJune 3, 2026
2 hours ago
The 4 Best Hair Loss Treatments for Women in 2026: Tested for Results and Regrowth
HealthDietary Supplements
The 4 Best Hair Loss Treatments for Women in 2026: Tested for Results and Regrowth
By Christina SnyderJune 3, 2026
3 hours ago
The 4 Best Scalp Massagers for Hair Growth: Tested and Reviewed
HealthDietary Supplements
The 4 Best Scalp Massagers for Hair Growth: Tested and Reviewed
By Emily PharesJune 3, 2026
3 hours ago
dr. oz
HealthWhite House
Dr. Oz on why Trump appointed a real-estate heir as acting intelligence chief: ‘I think Bill’s a great guy. I know him socially’
By Will Weissert, Josh Boak and The Associated PressJune 3, 2026
7 hours ago
Create Creatine Gummies Review (2026): Tasted and Tested by Experts
HealthDietary Supplements
Create Creatine Gummies Review (2026): Tasted and Tested by Experts
By Christina SnyderJune 2, 2026
1 day ago
Transparent Labs Probiotics Review (2026): RD Reviewed
HealthDietary Supplements
Transparent Labs Probiotics Review (2026): RD Reviewed
By Emily PharesJune 2, 2026
1 day ago

Most Popular

Social Security unraveling: 7,100 workers sacked, performance metrics retired, disability claims falling
North America
Social Security unraveling: 7,100 workers sacked, performance metrics retired, disability claims falling
By Katie Savin, Callie Freitag, Matthew Borus and The ConversationJune 2, 2026
1 day ago
Erin Brockovich, the activist who defeated a utility giant and inspired a Julia Roberts film, is pushing data centers to be more transparent
Environment
Erin Brockovich, the activist who defeated a utility giant and inspired a Julia Roberts film, is pushing data centers to be more transparent
By Marco Quiroz-GutierrezJune 1, 2026
2 days ago
'Where we are today is frightening': a Pulitzer-winning historian sees a doomsday scenario involving China and the national debt
Banking
'Where we are today is frightening': a Pulitzer-winning historian sees a doomsday scenario involving China and the national debt
By Nick LichtenbergJune 2, 2026
2 days ago
Cognizant CEO says AI is remaking middle managers into player-coaches who can 'both  execute and develop others'
Newsletters
Cognizant CEO says AI is remaking middle managers into player-coaches who can 'both execute and develop others'
By Diane BradyJune 2, 2026
2 days ago
Current price of oil as of June 2, 2026
Personal Finance
Current price of oil as of June 2, 2026
By Joseph HostetlerJune 2, 2026
1 day ago
Current price of gold as of June 2, 2026
Personal Finance
Current price of gold as of June 2, 2026
By Danny BakstJune 2, 2026
1 day ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.