• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
Tech

Drugmaker Alexion boosts its rare drug pipeline with $8.4 billion deal

By
Reuters
Reuters
Down Arrow Button Icon
By
Reuters
Reuters
Down Arrow Button Icon
May 6, 2015, 8:10 AM ET
Inside of a Gilead Sciences Lab
An automated machine works on purification of potential hepatitis C virus drug candidate at the Gilead Sciences Inc. lab in Foster City, California, U.S., on Wednesday, Feb. 8, 2012. Gilead acquired Pharmasset Inc. last month for its experimental hepatitis C treatments as it aims to compete with other drugmakers like Bristol-Myers Squibb Co. and Merck & Co. to develop a new class of oral cures for hepatitis C to replace older drugs that require injections. Photographer: David Paul Morris/Bloomberg via Getty ImagesPhotograph by David Paul Morris — Bloomberg via Getty Images

Drugmaker Alexion Pharmaceuticals Inc said Wednesday it would buy Synageva BioPharma Corp for $8.4 billion to boost its rare drug pipeline.

Alexion’s cash-and-stock offer values Synageva at $225.92 per share — more than double of Synageva closing price of $95.87 on Tuesday.

Makers of drugs that treat rare diseases are attractive because they typically charge hefty premiums for their products.

The deal will give Alexion access to Kanuma – Synageva’s treatment for a rare disease called Lysosomal Acid Lipase Deficiency, where build-up of fatty material in the blood and liver causes unexpected complications and some times early death.

Kanuma’s marketing application is being reviewed in the United States and Europe.

The deal is the latest in a string of M&As in the healthcare sector this year.

Recent deals involving rare disease companies include Teva Pharmaceutical Industries Inc’s $3.5 billion purchase of Auspex Pharmaceuticals in March and Shire’s acquisition of NPS Pharmaceuticals for $5.2 billion in January.

Alexion is offering $115 in cash and 0.6581 of its shares for each share of Synageva.

The deal is expected to add to Alexion’s 2018 profit, while allowing $150 million in cost savings in 2017, the companies said in a statement.

Alexion has received committed financing of $3.5 billion from Bank of America Merrill Lynch and JPMorgan for the deal.

Lazard and JPMorgan were Alexion’s financial advisers, while Goldman Sachs advised Synageva.

Wachtell Lipton Rosen & Katz is Alexion’s legal counsel, while Sullivan & Cromwell LLP and Ropes & Gray LLP are Synageva’s legal counsel.

About the Author
By Reuters
See full bioRight Arrow Button Icon

Latest in Tech

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Fortune Secondary Logo
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • Future 50
  • World’s Most Admired Companies
  • See All Rankings
Sections
  • Finance
  • Fortune Crypto
  • Features
  • Leadership
  • Health
  • Commentary
  • Success
  • Retail
  • Mpw
  • Tech
  • Lifestyle
  • CEO Initiative
  • Asia
  • Politics
  • Conferences
  • Europe
  • Newsletters
  • Personal Finance
  • Environment
  • Magazine
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
  • Group Subscriptions
About Us
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
Fortune Secondary Logo
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Latest in Tech

hormuz
CommentaryOil
Hung up on Hormuz: the old-world order of oil was just shattered by the closing of Iran’s key global chokepoint
By Siddharth MisraMarch 6, 2026
45 minutes ago
Big TechChina
OpenAI investor Vinod Khosla, a vocal Trump critic, agrees with the president on AI and China: ‘We are in a techno-economic war’
By Nicholas GordonMarch 6, 2026
1 hour ago
C-SuiteMcDonald's
McDonald’s CEO did a burger taste test that became a cautionary tale for execs. But there’s a silver lining
By Rachel VentrescaMarch 6, 2026
2 hours ago
travis
Commentaryelectrical grid
I help manage one of the world’s most constrained supply chains, up close to the defining energy bottleneck of the decade
By Travis EdmondsMarch 6, 2026
2 hours ago
The Block Ink logo is displayed on a mobile phone with the company's bran
AIFinance
Exclusive: Block’s CFO explains the AI leaps over 18 months that led to the decision to slash nearly half its workforce 
By Sheryl EstradaMarch 6, 2026
2 hours ago
AIVenture Capital
Venture dollars to female founders doubled to a record $73 billion last year—but Anthropic and Scale AI skewed the data
By Lily Mae LazarusMarch 6, 2026
2 hours ago

Most Popular

placeholder alt text
Success
Uber CEO says his ‘really demanding’ work culture includes expecting employees to answer his emails over the weekend: ‘Don’t come here if you want to coast’
By Emma BurleighMarch 4, 2026
2 days ago
placeholder alt text
Health
Palantir and other tech companies are stocking offices with nicotine products to increase worker productivity
By Catherina GioinoMarch 4, 2026
2 days ago
placeholder alt text
Newsletters
The Iran war is giving rise to a centuries-old economic theory—and laying waste to the WTO-based world order
By Diane BradyMarch 5, 2026
1 day ago
placeholder alt text
Economy
Trump's loss of $1.7 trillion in tariff revenue will send the national debt to $58 trillion by 2036, think tank projects
By Nick LichtenbergMarch 5, 2026
19 hours ago
placeholder alt text
AI
OpenAI investor Vinod Khosla predicts today’s 5-year-olds won’t ever need to get jobs thanks to AI
By Sasha RogelbergMarch 4, 2026
2 days ago
placeholder alt text
Success
Tech investor Bill Gurley says workers who went through the ‘college conveyor belt’ and chased safe jobs are at high risk of AI automation
By Emma BurleighMarch 3, 2026
3 days ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.