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Merck brought in $39.8 billion in 2016 global sales. The U.S. drug giant’s wide-ranging portfolio was crucial to that haul but the company’s next-generation cancer immunotherapy treatment, Keytruda, is what really set it apart last year. The therapy bested rival Bristol-Myers Squibb’s competing Opdivo in the critical lung cancer space, according to clinical trial data, making it (and Merck) one of the most formidable players in the latest strike on cancer.

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Kenneth C. Frazier

CEO Title

Chairman, President & Chief Executive Officer


Health Care



HQ Location

Kenilworth, NJ

Years on Fortune 500 List




Profile provided by S&P Global.
Key Financials (Last Fiscal Year)
$ millions% change
Revenues ($M)$39,8070.8%
Profits ($M)$3,920.0-11.8%
Assets ($M)$95,377
Total Stockholder Equity ($M)$40,088
Market Value — as of March 31, 2017 ($M)$174,454
Profit Ratios
Profit as % of Revenues9.8%
Profits as % of Assets4.1%
Profits as % of Stockholder Equity9.8%
Earnings Per Share (Last Fiscal Year)
Earnings Per Share ($)1.41
EPS % Change (from 2015)-9.6%
EPS % Change (5 year annual rate)-6.9%
EPS % Change (10 year annual rate)-3.6%
Total Return
Total Return to Investors (2016)15.1%
Total Return to Investors (5 year, annualized)13.2%
Total Return to Investors (10 year, annualized)7.0%
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